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  1. There is limited data on factors associated with loss to follow-up (LTFU) of health care workers (HCWs) following occupational exposure to HIV, and most studies were conducted in an era when poorly tolerated a...

    Authors: Nectarios Sophocles Papavarnavas, Kathryn Manning, Fahd Conrad, Milah Govender and Gary Maartens

    Citation: AIDS Research and Therapy 2017 14:23

    Content type: Research

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  2. People with HIV with access to treatment are growing older and living healthier lives than in the past, and while health improvements and increased survival rates are welcome, the psychological and social cons...

    Authors: Jose Catalan, Veronica Tuffrey, Damien Ridge and Dana Rosenfeld

    Citation: AIDS Research and Therapy 2017 14:22

    Content type: Research

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  3. To evaluate psychometric characteristics and cross-sectional and longitudinal validity of the 7-item PROMIS® Fatigue Short Form and additional fatigue items among people living with HIV (PLWH) in a nationally dis...

    Authors: L. E. Gibbons, R. Fredericksen, D. S. Batey, L. Dant, T. C. Edwards, K. H. Mayer, W. C. Mathews, L. S. Morales, M. J. Mugavero, F. M. Yang, E. Paez, M. M. Kitahata, D. L. Patrick, H. M. Crane and P. K. Crane

    Citation: AIDS Research and Therapy 2017 14:21

    Content type: Research

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  4. Incomplete adherence to antiretroviral therapy (ART) results in virologic failure and resistance. It remains unclear which adherence measure best predicts these outcomes. We compared six patient-reported and o...

    Authors: Catherine Orrell, Karen Cohen, Rory Leisegang, David R. Bangsberg, Robin Wood and Gary Maartens

    Citation: AIDS Research and Therapy 2017 14:20

    Content type: Research

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  5. Evaluation of medication efficacy and safety is an essential guarantee to successful therapeutic outcome in public health practices. However, larger distribution chain supply in developing countries such as Ca...

    Authors: M. P. Ngogang Djobet, David Singhe, Julienne Lohoue, Christopher Kuaban, Jeanne Ngogang and Ernest Tambo

    Citation: AIDS Research and Therapy 2017 14:19

    Content type: Research

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  6. Psychosocial factors have been linked with loss to follow-up (LTFU) and clinical outcomes among people living with HIV (PLH), however little is known about the effect of psychosocial support on LTFU among PLH ...

    Authors: Hellen N. Siril, Sylvia F. Kaaya, Mary Kay Smith Fawzi, Expeditho Mtisi, Magreat Somba, Japheth Kilewo, Ferdinand Mugusi, Anna Minja, Anna Kaale and Jim Todd

    Citation: AIDS Research and Therapy 2017 14:18

    Content type: Research

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  7. Early detection of pediatric HIV through uptake of infant HIV testing is critical for access to treatment and child survival. While structural barriers have been well described, a greater understanding of soci...

    Authors: Karen M. Hampanda, Abigail M. Nimz and Lisa L. Abuogi

    Citation: AIDS Research and Therapy 2017 14:17

    Content type: Research

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  8. Adhering 95% and above of antiretroviral therapy reduces the rate of disease progression and death among people’s living human immunodeficiency virus. Though manifold factors have reported as determinant facto...

    Authors: Berhe Beyene Gebrezgabher, Yigzaw Kebede, Melaku Kindie, Desalegn Tetemke, Mebrahtu Abay and Yalemzewod Assefa Gelaw

    Citation: AIDS Research and Therapy 2017 14:16

    Content type: Research

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  9. Progression rates from initial HIV-1 infection to advanced AIDS vary significantly among infected individuals. A distinct subgroup of HIV-1-infected individuals—termed viremic non-progressors (VNP) or controll...

    Authors: Jan Weber, Richard M. Gibson, Lenka Sácká, Dmytro Strunin, Jan Hodek, Jitka Weberová, Marcela Pávová, David J. Alouani, Robert Asaad, Benigno Rodriguez, Michael M. Lederman and Miguel E. Quiñones-Mateu

    Citation: AIDS Research and Therapy 2017 14:15

    Content type: Research

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  10. Adherence and CD4 cell count change measure the progression of the disease in HIV patients after the commencement of HAART. Lack of information about associated factors on adherence to HAART and CD4 cell count...

    Authors: Awoke Seyoum, Principal Ndlovu and Zewotir Temesgen

    Citation: AIDS Research and Therapy 2017 14:14

    Content type: Research

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  11. Early diagnosis of HIV associated lymphoma is challenging because the definitive diagnostic procedure of biopsy, requires skills and equipment that are not readily available. As a consequence, diagnosis may be...

    Authors: Paul Buyego, Lydia Nakiyingi, Henry Ddungu, Stephen Walimbwa, Damalie Nalwanga, Steven J Reynolds and Rosalind Parkes-Ratanshi

    Citation: AIDS Research and Therapy 2017 14:13

    Content type: Research

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  12. Moringa oleifera Lam., an herb commonly consumed by HIV-infected people on antiretroviral therapy, inhibits cytochrome P450 3A4, 1A2 and 2D6 activity in vitro; and may alter the pharma...

    Authors: Tsitsi G. Monera-Penduka, Charles C. Maponga, Alan R. Wolfe, Lubbe Wiesner, Gene D. Morse and Charles F. B. Nhachi

    Citation: AIDS Research and Therapy 2017 14:12

    Content type: Research

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  13. Occult hepatitis B infection (OBI) among HIV positive patients varies widely in different geographic regions. We undertook a study to determine the prevalence of occult hepatitis B infection among HIV infected...

    Authors: George Gachara, Tshifhiwa Magoro, Lufuno Mavhandu, Emmaculate Lum, Helen K. Kimbi, Roland N. Ndip and Pascal O. Bessong

    Citation: AIDS Research and Therapy 2017 14:11

    Content type: Research

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  14. Approximately 0.8% of adults aged 18–49 in Myanmar are seropositive for Human Immunodeficiency Virus (HIV). Identifying the demographic, epidemiological and clinical characteristics of people living with HIV (...

    Authors: Ne Myo Aung, Josh Hanson, Tint Tint Kyi, Zaw Win Htet, David A. Cooper, Mark A. Boyd, Mar Mar Kyi and Htin Aung Saw

    Citation: AIDS Research and Therapy 2017 14:10

    Content type: Research

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  15. Late presentation (LP) at the time of HIV diagnosis is defined as presentation with AIDS whatever the CD4 cell count or with CD4 <350 cells/mm. The objective of our study was to assess the prevalence of non-in...

    Authors: Giovanni Guaraldi, Stefano Zona, Marianna Menozzi, Thomas D. Brothers, Federica Carli, Chiara Stentarelli, Giovanni Dolci, Antonella Santoro, Ana Rita Domingues Da Silva, Elisa Rossi, Julian Falutz and Cristina Mussini

    Citation: AIDS Research and Therapy 2017 14:8

    Content type: Research

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  16. Antigen-induced activation and proliferation of HIV-1-infected cells is hypothesized to be a mechanism of HIV persistence during antiretroviral therapy. The objective of this study was to determine if prolifer...

    Authors: Thor A. Wagner, Hannah C. Huang, Christen E. Salyer, Kelly M. Richardson, Adriana Weinberg, Sharon Nachman and Lisa M. Frenkel

    Citation: AIDS Research and Therapy 2017 14:7

    Content type: Short report

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  17. The prevalence of bipolar disorder in HIV-infected patients is higher than the general population. Lithium is the most effective mood stabiliser, while tenofovir disoproxil fumarate (TDF) is frequently used as...

    Authors: Eric H. Decloedt, Maia Lesosky, Gary Maartens and John A. Joska

    Citation: AIDS Research and Therapy 2017 14:6

    Content type: Research

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  18. Tenofovir (TDF) based regimen was reported to have better immunological outcomes. Unfortunately, there is limited information regarding the immunologic outcome associated with this regimen in Ethiopia, as its ...

    Authors: Teshale Ayele, Habtemu Jarso and Girma Mamo

    Citation: AIDS Research and Therapy 2017 14:5

    Content type: Research

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  19. To understand HIV-1 drug resistance in 11 prefectures of Hebei Province, China, we implemented a cross-sectional HIV-1 molecular epidemiological survey.

    Authors: Xinli Lu, Hongru Zhao, Yuqi Zhang, Wei Wang, Cuiying Zhao, Yan Li, Lin Ma, Ze Cui and Suliang Chen

    Citation: AIDS Research and Therapy 2017 14:4

    Content type: Research

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  20. Regular monitoring of HIV patients who are receiving antiretroviral therapy (ART) is required to ensure patient benefits and the long-term effectiveness and sustainability of ART programs. Prompted by WHO reco...

    Authors: Minh D. Pham, Lorena Romero, Bruce Parnell, David A. Anderson, Suzanne M. Crowe and Stanley Luchters

    Citation: AIDS Research and Therapy 2017 14:3

    Content type: Review

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  21. Codon usage bias has been described for various organisms and is thought to contribute to the regulation of numerous biological processes including viral infections. HIV-1 codon usage has been previously shown...

    Authors: Navaneethan Palanisamy, Nathan Osman, Frédéric Ohnona, Hong-Tao Xu, Bluma Brenner, Thibault Mesplède and Mark A. Wainberg

    Citation: AIDS Research and Therapy 2017 14:2

    Content type: Research

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  22. This cross-sectional study took place in the integrated tuberculosis (TB) clinic of a large outpatient clinic for HIV-infected patients in Kampala, Uganda. The purpose of this study was to describe the proport...

    Authors: Amrei von Braun, Christine Sekaggya-Wiltshire, Alexandra U. Scherrer, Brian Magambo, Andrew Kambugu, Jan Fehr and Barbara Castelnuovo

    Citation: AIDS Research and Therapy 2017 14:1

    Content type: Research

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  23. Cryptococcosis has been one of the most common opportunistic infections and causes of mortality among HIV-infected patients, especially in resource-limited countries. Cryptococcal meningitis is the most common...

    Authors: Sirawat Srichatrapimuk and Somnuek Sungkanuparph

    Citation: AIDS Research and Therapy 2016 13:42

    Content type: Review

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  24. New simian–human immunodeficiency chimeric viruses with an HIV-1 env (SHIVenv) are critical for studies on HIV pathogenesis, vaccine development, and microbicide testing. Macaques are typically exposed to sing...

    Authors: Kendall C. Krebs, Meijuan Tian, Mohammed Asmal, Binhua Ling, Kenneth Nelson, Kenneth Henry, Richard Gibson, Yuejin Li, Weining Han, Robin J. Shattock, Ronald S. Veazey, Norman Letvin, Eric J. Arts and Yong Gao

    Citation: AIDS Research and Therapy 2016 13:41

    Content type: Research

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  25. Gynaecomastia is associated with exposure to antiretroviral therapy (ART), in particular efavirenz. There is limited data on clinical characteristics of patients with ART-associated gynaecomastia in resource-l...

    Authors: Christine Njuguna, Annoesjka Swart, Marc Blockman, Gary Maartens, Briony Chisholm, Annemie Stewart, Anri Uys and Karen Cohen

    Citation: AIDS Research and Therapy 2016 13:40

    Content type: Research

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  26. In many countries in Asia, the HIV epidemic is in a concentrated phase, with high prevalence in certain risk groups, such as men who inject drugs. There is also a rapid increase of HIV among women. The latter ...

    Authors: Vu Van Tam, Do Duy Cuong, Tobias Alfven, Ho Dang Phuc, Nguyen Thi Kim Chuc, Nguyen Phuong Hoa, Vinod Diwan and Mattias Larsson

    Citation: AIDS Research and Therapy 2016 13:39

    Content type: Research

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  27. The success of antiretroviral therapy in resource-scarce settings is an illustration that complex healthcare interventions can be successfully delivered even in fragile health systems. Documenting the success ...

    Authors: Jared O. Mecha, Elizabeth N. Kubo, Lucy W. Nganga, Peter N. Muiruri, Lilian N. Njagi, Immaculate N. Mutisya, Justine J. Odionyi, Syokau C. Ilovi, Mary Wambui, Christopher Githu, Richard Ngethe, Elizabeth M. Obimbo and Zipporah W. Ngumi

    Citation: AIDS Research and Therapy 2016 13:38

    Content type: Research

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  28. After 30 years, the human immunodeficiency virus (HIV) remains an epidemic of global concern. To support the increasing emphasis on biomedical interventions for prevention requires a renewed and reframed focus...

    Authors: Sanyukta Mathur, Dina Romo, Mariko Rasmussen, Neema Nakyanjo, Fred Nalugoda and John S. Santelli

    Citation: AIDS Research and Therapy 2016 13:37

    Content type: Research

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  29. CD4 cells are a type of white blood cells that plays a significant role in protecting humans from infectious diseases. Lack of information on associated factors on CD4 cell count reduction is an obstacle for i...

    Authors: Awoke Seyoum, Principal Ndlovu and Temesgen Zewotir

    Citation: AIDS Research and Therapy 2016 13:36

    Content type: Research

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  30. Human immunodeficiency virus (HIV) epidemic has undoubtedly increased the incidence of tuberculosis (TB) globally, posing a formidable global health challenge affecting 1.2 million cases. Pulmonary TB assumes ...

    Authors: Narendran Gopalan, Padmapriyadarsini Chandrasekaran, Soumya Swaminathan and Srikanth Tripathy

    Citation: AIDS Research and Therapy 2016 13:34

    Content type: Review

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  31. Research has demonstrated a link between alcohol use and risky sexual behaviour among different types of migrant populations. Therefore, research investigating risk factors associated with alcohol consumption ...

    Authors: Emilia Maria Vaz Martins-Fonteyn, Nina Sommerland, Herman Meulemans, Olivier Degomme, Ines Raimundo and Edwin Wouters

    Citation: AIDS Research and Therapy 2016 13:33

    Content type: Review

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  32. The aim of this study was to determine the effects of nutritional status at the start of highly active anti-retroviral therapy on treatment outcomes among HIV/AIDS patients taking HAART at Jimma University Spe...

    Authors: Sadikalmahdi Hussen, Tefera Belachew and Nezif Hussien

    Citation: AIDS Research and Therapy 2016 13:32

    Content type: Research

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  33. The first-generation integrase inhibitors (INIs) raltegravir (RAL) and elvitegravir (EVG) have shown efficacy against HIV infection, but they have the limitations of once-more daily dosing and extensive cross-...

    Authors: Junjun Jiang, Xi Xu, Wenqin Guo, Jinming Su, Jiegang Huang, Bingyu Liang, Hui Chen, Ning Zang, Yanyan Liao, Li Ye and Hao Liang

    Citation: AIDS Research and Therapy 2016 13:30

    Content type: Review

    Published on:

  34. Over the last decade, Ethiopia adopted different strategies of prevention of mother to child transmission of HIV (PMTCT). Prior to implementation of Option A in 2011, there was no provision of prophylaxis for ...

    Authors: Tolessa Olana, Tigist Bacha, Walelign Worku and Birkneh Tilahun Tadesse

    Citation: AIDS Research and Therapy 2016 13:29

    Content type: Research

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  35. WHO recommends using Tenofovir containing first line antiretroviral therapy (ART), however, Tenofovir has been reported to be associated with renal impairment and dysfunction. We compared renal function among ...

    Authors: Tino Salome, Ivan Kasamba, Billy Nsubuga Mayanja, Patrick Kazooba, Jackson Were, Pontiano Kaleebu and Paula Munderi

    Citation: AIDS Research and Therapy 2016 13:28

    Content type: Research

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  36. After a period where it was recommended to start antiretroviral therapy (ART) early, the CD4 threshold for treating asymptomatic adults dropped to 200/mm3 at the beginning of the 2000s. This was mostly due to a g...

    Authors: Serge P. Eholié, Anani Badje, Gérard M. Kouame, Jean-Baptiste N’takpe, Raoul Moh, Christine Danel and Xavier Anglaret

    Citation: AIDS Research and Therapy 2016 13:27

    Content type: Review

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  37. People who inject drugs (PWID) living with HIV often experience sub-optimal antiretroviral therapy (ART) treatment outcomes, including HIV plasma viral load (PVL) rebound. While previous studies have identifie...

    Authors: Will Small, M. J. Milloy, Ryan McNeil, Lisa Maher and Thomas Kerr

    Citation: AIDS Research and Therapy 2016 13:26

    Content type: Research

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  38. Antiretroviral therapy (ART) treatment interruptions lead to poor clinical outcomes with unplanned or unstructured TIs (uTIs) likely to be underreported. This study describes; uTIs, their risk factors and asso...

    Authors: James H. McMahon, Tim Spelman, Nathan Ford, Jane Greig, Anita Mesic, Charles Ssonko, Esther C. Casas and Daniel P. O’Brien

    Citation: AIDS Research and Therapy 2016 13:25

    Content type: Research

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  39. To optimise care HIV patients need to be promptly initiated on antiretroviral therapy (ART) and subsequently retained on treatment. In this study we report on the interval between enrolment and treatment initi...

    Authors: Jeremy Philip Brown, Bagrey Ngwira, Terence Tafatatha, Amelia Catharine Crampin, Neil French and Olivier Koole

    Citation: AIDS Research and Therapy 2016 13:24

    Content type: Research

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  40. Tuberculosis (TB) has been the most common opportunistic infection and cause of mortality among HIV-infected patients, especially in resource-limited countries. Clinical manifestations of TB vary and depend on...

    Authors: Weerawat Manosuthi, Surasak Wiboonchutikul and Somnuek Sungkanuparph

    Citation: AIDS Research and Therapy 2016 13:22

    Content type: Review

    Published on:

  41. Despite the combined antiretroviral therapy has improved the length and quality of life of HIV infected patients, the survival of these patients is always decreased compared with the general population. This i...

    Authors: Gabriella d’Ettorre, Giancarlo Ceccarelli, Paolo Pavone, Pietro Vittozzi, Gabriella De Girolamo, Ivan Schietroma, Sara Serafino, Noemi Giustini and Vincenzo Vullo

    Citation: AIDS Research and Therapy 2016 13:21

    Content type: Review

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  42. Cognitive function is reported to improve after the initiation of combination antiretroviral therapy (cART). Data on the evolution of such changes are limited. We assessed the dynamics of changes in cognitive ...

    Authors: Borja Mora-Peris, Elizabeth Stevens, Francesca Ferretti, Jonathan Underwood, Stephen Taylor and Alan Winston

    Citation: AIDS Research and Therapy 2016 13:20

    Content type: Short report

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  43. Over the past 10 years, extensive work has been carried out in the field of microbial translocation in HIV infection, ranging from studies on its clinical significance to investigations on its pathogenic featu...

    Authors: Camilla Tincati, Daniel C. Douek and Giulia Marchetti

    Citation: AIDS Research and Therapy 2016 13:19

    Content type: Review

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  44. To describe the development and the psychometric properties of the Istituto Superiore di Sanità-HIV symptoms scale (lSS-HIV symptoms scale).

    Authors: Raffaella Bucciardini, Katherina Pugliese, Daniela Francisci, Andrea Costantini, Elisabetta Schiaroli, Miriam Cognigni, Chiara Tontini, Stefano Lucattini, Luca Fucili, Massimiliano Di Gregorio, Marco Mirra, Vincenzo Fragola, Sara Pompili, Rita Murri and Stefano Vella

    Citation: AIDS Research and Therapy 2016 13:18

    Content type: Short report

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  45. In the ANRS EASIER trial where treatment-experienced patients switched from enfuvirtide (ENF) to raltegravir (RAL), a high incidence of transaminase elevation was reported in the RAL arm.

    Authors: Nathalie de Castro, Joséphine Braun, Isabelle Charreau, Alain Lafeuillade, Jean-Paul Viard, Clotilde Allavena, Jean-Pierre Aboulker and Jean-Michel Molina

    Citation: AIDS Research and Therapy 2016 13:17

    Content type: Research

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  46. The uncertain etiology of HIV viral load (VL) blips may lead to increased use of clinical resources. We evaluated the association of self-reported adherence (SRA) and antiretroviral (ART) drug levels on blip o...

    Authors: Aaron Farmer, Xun Wang, Anuradha Ganesan, Robert G. Deiss, Brian K. Agan, Thomas A. O’Bryan, Kevin Akers and Jason F. Okulicz

    Citation: AIDS Research and Therapy 2016 13:16

    Content type: Research

    Published on: