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  1. Content type: Research

    Men who have sex with men (MSM) are amongst populations at-risk for HIV acquisition in Thailand. In youth MSM (aged 15–24 years), the incidence of HIV infection has substantially increased. However, data on HI...

    Authors: Thana Khawcharoenporn, Suteera Mongkolkaewsub, Chanon Naijitra, Worawoot Khonphiern, Anucha Apisarnthanarak and Nittaya Phanuphak

    Citation: AIDS Research and Therapy 2019 16:13

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  2. Content type: Review

    Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa. Several previous studies on tenofovir-associated k...

    Authors: Takudzwa J. Mtisi, Chiratidzo E. Ndhlovu, Chiedza C. Maponga and Gene D. Morse

    Citation: AIDS Research and Therapy 2019 16:12

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  3. Content type: Methodology

    As in non-infected subjects, statins and aspirin have a pivotal preventive role in reducing the cardiovascular related morbidity and mortality in HIV infected patients. The persistence of immune activation in ...

    Authors: P. Maggi, G. V. De Socio, S. Cicalini, M. D’Abbraccio, G. Dettorre, A. Di Biagio, C. Martinelli, G. Nunnari, S. Rusconi, L. Sighinolfi, V. Spagnuolo and N. Squillace

    Citation: AIDS Research and Therapy 2019 16:11

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  4. Content type: Research

    Presence of isolated anti-HBc antibody is common in HIV-infected patients in endemic areas and could be caused by prior HBV infection with loss of anti-HBs antibody. The role of vaccination in these patients r...

    Authors: Nattinee Laksananun, Jutarat Praparattanapan, Wilai Kotarathititum, Khuanchai Supparatpinyo and Romanee Chaiwarith

    Citation: AIDS Research and Therapy 2019 16:10

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  5. Content type: Research

    Practical screening strategies are necessary to detect neurocognitive impairment of all severities in HIV populations, which remains prevalent despite highly active antiretroviral therapy and requires full neu...

    Authors: Lai Gwen Chan, Mei Jing Ho, Yijun Carol Lin, Yining Ong and Chen Seong Wong

    Citation: AIDS Research and Therapy 2019 16:9

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  6. Content type: Research

    The World Health Organization and Tanzanian National Guidelines for HIV and AIDS management, recommends provider initiated testing and counseling for HIV at any point of health care contact. In Tanzania, over ...

    Authors: Juma Ramadhani, Hendry R. Sawe, Said S. Kilindimo, Juma A. Mfinanga and Ellen J. Weber

    Citation: AIDS Research and Therapy 2019 16:8

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  7. Content type: Research

    Long-term success of cART is possible if the regimen is convenient and less-toxic. This study assessed the efficacy and safety of switching from a first-line NNRTI or boosted PI-based regimens to RPV-based reg...

    Authors: Sivaporn Gatechompol, Anchalee Avihingsanon, Tanakorn Apornpong, Win Min Han, Stephen J. Kerr and Kiat Ruxrungtham

    Citation: AIDS Research and Therapy 2019 16:7

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  8. Content type: Research

    This study aimed to investigate the prevalence of HIV late presentation and advanced HIV disease and to identify the factors associated with HIV late presentation and advanced HIV disease among patients with n...

    Authors: Xi Hu, Bingyu Liang, Chongxing Zhou, Junjun Jiang, Jiegang Huang, Chuanyi Ning, Jie Liu, Bo Zhou, Ning Zang, Jinzhen Lai, Rongfeng Chen, Yanyan Liao, Peijiang Pan, Xin Liu, Guanghua Lan, Xianwu Pang…

    Citation: AIDS Research and Therapy 2019 16:6

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  9. Content type: Short Report

    High rates of non-nucleoside reverse transcriptase inhibitors (NNRTI) resistance was a key consideration in the WHO policies transitioning first-line regimens to include integrase inhibitors (dolutegravir [DTG...

    Authors: Sarah E. Rutstein, Jane S. Chen, Julie A. E. Nelson, Samuel Phiri, William C. Miller and Mina C. Hosseinipour

    Citation: AIDS Research and Therapy 2019 16:5

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  10. Content type: Research

    Despite the advances in therapy, the occurrence of drug-resistant human immunodeficiency virus type 1 (HIV-1) is a major obstacle to successful treatment. This study aimed to characterize the genetic diversity...

    Authors: Larissa Danielle Bahls, Pedro Henrique Canezin, Edna Maria Vissoci Reiche, José Carlos Couto Fernandez, José Ricardo Colleti Dias, Vera Alice Fernandes Meneguetti, Luis Toshio Ueda and Dennis Armando Bertolini

    Citation: AIDS Research and Therapy 2019 16:4

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  11. Content type: Research

    Our understanding of HIV-1 and antiretroviral treatment (ART) is strongly biased towards subtype B, the predominant subtype in North America and western Europe. Efforts to characterize the response to first-li...

    Authors: Art F. Y. Poon, Emmanuel Ndashimye, Mariano Avino, Richard Gibson, Cissy Kityo, Fred Kyeyune, Immaculate Nankya, Miguel E. Quiñones-Mateu and Eric J. ARTS

    Citation: AIDS Research and Therapy 2019 16:3

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  12. Content type: Research

    Antiretroviral therapy (ART) use by people living with HIV reduces HIV transmission, morbidity, mortality, and improves quality of life. Good ART adherence is required to achieve these benefits. We investigate...

    Authors: Dominic Bukenya, Billy Nsubuga Mayanja, Sarah Nakamanya, Richard Muhumuza and Janet Seeley

    Citation: AIDS Research and Therapy 2019 16:2

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  13. Content type: Research

    HLA-B*57:01 screening was added to clinical care guidelines in 2008 to reduce the risk of hypersensitivity reaction from abacavir. The uptake of HLA-B*57:01 screening and incidence of hypersensitivity reaction...

    Authors: Karam Mounzer, Ricky Hsu, Jennifer S. Fusco, Laurence Brunet, Cassidy E. Henegar, Vani Vannappagari, Chris M. Stainsby, Mark S. Shaefer, Leigh Ragone and Gregory P. Fusco

    Citation: AIDS Research and Therapy 2019 16:1

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  14. Content type: Case Report

    The management of visceral leishmaniasis (VL) in HIV-infected patients is often complex with patients experiencing higher mortality rates, more toxic side effects and a higher possibility of treatment failure ...

    Authors: Antonio Mastroianni, Paolo Gaibani, Giada Rossini, Caterina Vocale, Maria Carla Re, Gianfranco Ravaglia, Vittorio Sambri and Stefania Varani

    Citation: AIDS Research and Therapy 2018 15:27

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  15. Content type: Short Report

    Voluntary medical male circumcision (VMMC) is a critical component of HIV prevention. VMMC policies have achieved initial targets in adult men yet continue to fall short in reaching younger men and adolescents.

    Authors: O. Galárraga, P. Shah, M. Wilson-Barthes, D. Ayuku and P. Braitstein

    Citation: AIDS Research and Therapy 2018 15:24

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  16. Content type: Research

    Studies relating to long-term virological outcomes among children on first-line antiretroviral therapy (ART) from low and middle-income countries are limited.

    Authors: Padmapriyadarsini Chandrasekaran, Anita Shet, Ramalingam Srinivasan, G. N. Sanjeeva, Sudha Subramanyan, Suba Sunderesan, Karunaianantham Ramesh, Bindu Gopalan, Elumalai Suresh, Navaneethan Poornagangadevi, Luke E. Hanna, Chockalingam Chandrasekar, Christine Wanke and Soumya Swaminathan

    Citation: AIDS Research and Therapy 2018 15:23

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  17. Content type: Research

    Like other countries, Tanzania instituted mobile and outreach testing approaches to address low HIV testing rates at health facilities and enhance linkage to care. Available evidence from hard-to-reach rural s...

    Authors: Erica S. Sanga, Ferdinand C. Mukumbang, Adiel K. Mushi, Willyhelmina Olomi, Wondwossen Lerebo and Christina Zarowsky

    Citation: AIDS Research and Therapy 2018 15:21

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  18. Content type: Research

    Adolescents living with HIV on antiretroviral therapy (ART) have worse treatment adherence, viral suppression, and mortality rates compared to adults. This study investigated factors associated with viral non-...

    Authors: Kolab Chhim, Gitau Mburu, Sovannary Tuot, Ratana Sopha, Vohith Khol, Pheak Chhoun and Siyan Yi

    Citation: AIDS Research and Therapy 2018 15:20

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  19. Content type: Review

    The life expectancy of people living with HIV (PLHIV) has dramatically improved with effective and well-tolerated antiretroviral therapy. This presents a new challenge in caring for this patient population, wi...

    Authors: Mark Bloch

    Citation: AIDS Research and Therapy 2018 15:19

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  20. Content type: Research

    The widespread global access to antiretroviral drugs has led to considerable reductions in morbidity and mortality but, unfortunately, the risk of virologic failure increases with the emergence, and potential ...

    Authors: Nicholas Silver, Mary Paynter, Georgina McAllister, Maureen Atchley, Christine Sayir, John Short, Dane Winner, David J. Alouani, Freddie H. Sharkey, Kicki Bergefall, Kate Templeton, David Carrington and Miguel E. Quiñones-Mateu

    Citation: AIDS Research and Therapy 2018 15:18

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  21. Content type: Research

    To compare outcomes with single tablet regimens (STR) versus multi-tablet regimens (MTR) for human immunodeficiency virus (HIV) treatment using published data.

    Authors: Patrick G. Clay, Wei C. Yuet, Christiane H. Moecklinghoff, Inge Duchesne, Krzysztof L. Tronczyński, Sandip Shah and Dong Shao

    Citation: AIDS Research and Therapy 2018 15:17

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  22. Content type: Research

    Non-AIDS defining cancers (NADCs) have been an increasing cause of morbidity and mortality in patients with HIV. There is no data on the spectrum of NADCs in Mexico. We describe the type of neoplasms, clinical...

    Authors: P. Cornejo-Juárez, D. Cavildo-Jerónimo and P. Volkow-Fernández

    Citation: AIDS Research and Therapy 2018 15:16

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  23. Content type: Research

    While the effects of initiation of antiretroviral treatment (ART) on risky sexual behavior have been extensively studied, less is known about the long-term changes in risky sexual behavior over time in resourc...

    Authors: Stephen Okoboi, Barbara Castelnuovo, David M. Moore, Joseph Musaazi, Andrew Kambugu, Josephine Birungi, Pontiano Kaleebu, Mastula Nanfuka, Moses R. Kamya and Annelies Van Rie

    Citation: AIDS Research and Therapy 2018 15:15

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  24. Content type: Research

    It has been speculated that the prevalence of chemsex is increasing in men who have sex with men and that this may be playing a role in the spread of HIV.

    Authors: Chris Kenyon, Kristien Wouters, Tom Platteau, Jozefien Buyze and Eric Florence

    Citation: AIDS Research and Therapy 2018 15:14

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  25. Content type: Research

    Immune restoration is often incomplete after ART in HIV patients, both quantitatively and qualitatively. We studied the incidence and probability of CD4/CD8 normalization in an adult Thai HIV cohort and explor...

    Authors: Win Min Han, Tanakorn Apornpong, Stephen J. Kerr, Akarin Hiransuthikul, Sivaporn Gatechompol, Tanya Do, Kiat Ruxrungtham and Anchalee Avihingsanon

    Citation: AIDS Research and Therapy 2018 15:13

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  26. Content type: Research

    Extramarital sex is a potential driver of human immunodeficiency virus (HIV) transmission for long-term couples in sub-Saharan Africa. It is increasingly recognized that preventing sexual risk behaviours requi...

    Authors: Sally M. Mtenga, Constanze Pfeiffer, Marcel Tanner, Eveline Geubbels and Sonja Merten

    Citation: AIDS Research and Therapy 2018 15:12

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  27. Content type: Research

    The prevalence of HIV-1 resistance to antiretroviral therapies (ART) has declined in high-income countries over recent years, but drug resistance remains a substantial concern in many low and middle-income cou...

    Authors: Oliver T. Stirrup, David T. Dunn, Anna Tostevin, Caroline A. Sabin, Anton Pozniak, David Asboe, Alison Cox, Chloe Orkin, Fabiola Martin and Patricia Cane

    Citation: AIDS Research and Therapy 2018 15:11

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  28. Content type: Research

    While efficacy data exist, there are limited data on the outcomes of patients on third-line antiretroviral therapy (ART) in sub-Saharan Africa in actual practice. Being able to identify predictors of switch to...

    Authors: Denise Evans, Kamban Hirasen, Rebecca Berhanu, Given Malete, Prudence Ive, David Spencer, Sharlaa Badal-Faesen, Ian M. Sanne and Matthew P. Fox

    Citation: AIDS Research and Therapy 2018 15:10

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  29. Content type: Research

    As part of efforts to improve the prevention of mother-to-child transmission in Northern Uganda, we explored reasons for poor viral suppression among 122 pregnant and lactating women who were in care, received...

    Authors: Tamara Nsubuga-Nyombi, Simon Sensalire, Esther Karamagi, Judith Aloyo, John Byabagambi, Mirwais Rahimzai, Linda Kisaakye Nabitaka and Jacqueline Calnan

    Citation: AIDS Research and Therapy 2018 15:9

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  30. Content type: Research

    Understanding the circumstances of adolescents living with HIV is critical in designing adolescent-friendly services that will facilitate successful transition from pediatric to adult care. This study describe...

    Authors: Graham Toth, Gitau Mburu, Sovannary Tuot, Vohith Khol, Chanrith Ngin, Pheak Chhoun and Siyan Yi

    Citation: AIDS Research and Therapy 2018 15:8

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  31. Content type: Review

    HIV infection causes upregulation of markers of inflammation, immune activation and apoptosis of host adaptive, and innate immune cells particularly monocytes, natural killer (NK) and innate lymphoid cells (IL...

    Authors: Rose Nabatanzi, Stephen Cose, Moses Joloba, Sarah Rowland Jones and Damalie Nakanjako

    Citation: AIDS Research and Therapy 2018 15:7

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  32. Content type: Research

    To assess the prevalence of non-AIDS co-morbidities (NACs) and predictors of adverse health outcomes amongst people living with HIV in order to identify health needs and potential gaps in patient management.

    Authors: Derek J. Chan, Virginia Furner, Don E. Smith, Mithilesh Dronavalli, Rohan I. Bopage, Jeffrey J. Post and Anjali K. Bhardwaj

    Citation: AIDS Research and Therapy 2018 15:6

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  33. Content type: Research

    Criteria for the 2007 WHO algorithm for diagnosing tuberculosis among HIV-infected seriously ill patients are the presence of one or more danger signs (respiratory rate > 30/min, heart rate > 120/min, temperat...

    Authors: Rulan Griesel, Annemie Stewart, Helen van der Plas, Welile Sikhondze, Marc Mendelson and Gary Maartens

    Citation: AIDS Research and Therapy 2018 15:5

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  34. Content type: Research

    Despite the conventional approaches to HIV prevention being the bedrock for early reductions in HIV infections in Uganda, innovations that demonstrate reduction in risk to infection in vulnerable populations n...

    Authors: Esther Karamagi, Simon Sensalire, Juliana Nabwire, John Byabagambi, Alfred O. Awio, George Aluma, Mirwais Rahimzai, Jacqueline Calnan and Sheila Kyobutungi

    Citation: AIDS Research and Therapy 2018 15:4

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  35. Content type: Research

    Deep venous thrombosis (DVT) and its major complication pulmonary embolism (PE) are collectively known as venous thromboembolism. In Uganda, the prevalence of DVT among HIV patients has not been previously pub...

    Authors: Sosthene Tsongo Vululi, Samuel Bugeza, Muyinda Zeridah, Henry Ddungu, Akello Betty Openy, Mubiru Frank and Rosalind Parkes-Ratanshi

    Citation: AIDS Research and Therapy 2018 15:3

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  36. Content type: Research

    Mental health (MH) comorbidities reduce retention in care for persons living with HIV (PLWH) and are associated with poor health outcomes. Optimizing retention in primary care is vital, as poor retention is as...

    Authors: Lauren A. Saag, Ashutosh R. Tamhane, D. Scott Batey, Michael J. Mugavero and Ellen F. Eaton

    Citation: AIDS Research and Therapy 2018 15:1

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  37. Content type: Research

    We evaluate the impact of clinic-based PMTCT community support by trained lay health workers in addition to standard clinical care on PMTCT infant outcomes.

    Authors: Karl Peltzer, Stephen M. Weiss, Manasi Soni, Tae Kyoung Lee, Violeta J. Rodriguez, Ryan Cook, Maria Luisa Alcaide, Geoffrey Setswe and Deborah L. Jones

    Citation: AIDS Research and Therapy 2017 14:61

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  38. Content type: Research

    Antiretroviral therapy (ART) has modified the natural history of HIV-infection: the incidence of opportunistic infections (OIs) has decreased and mortality associated to HIV has improved dramatically. The reas...

    Authors: María Fernanda Álvarez Barreneche, Carlos Andrés Restrepo Castro, Alicia Hidrón Botero, Juan Pablo Villa Franco, Ivan Mauricio Trompa Romero, Laura Restrepo Carvajal, Alejandro Eusse García, Adriana Ocampo Mesa, Lina María Echeverri Toro, Glenys Patricia Porras Fernández de Castro, Jaime Mauricio Ramírez Rivera and Carlos Andrés Agudelo Restrepo

    Citation: AIDS Research and Therapy 2017 14:60

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  39. Content type: Research

    As a simplification strategy for treatment-experienced HIV-infected patients who have achieved virologic suppression on a multi-drug, multi-class antiretroviral regimen, the aim of this study was to evaluate t...

    Authors: Marianne Harris, Bruce Ganase, Birgit Watson, P. Richard Harrigan, Julio S. G. Montaner and Mark W. Hull

    Citation: AIDS Research and Therapy 2017 14:59

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  40. Content type: Short Report

    For patients on antiretroviral therapy (ART), treatment interruptions can impact patient outcomes and result in the accumulation of drug resistance mutations leading to virologic failure. There are minimal pub...

    Authors: Seema T. Meloni, Beth Chaplin, John Idoko, Oche Agbaji, Sulaimon Akanmu, Godwin Imade, Prosper Okonkwo, Robert L. Murphy and Phyllis J. Kanki

    Citation: AIDS Research and Therapy 2017 14:58

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  41. Content type: Research

    Plant extracts are sources of valuable compounds with biological activity, especially for the anti-proliferative activity against pathogens or tumor cells. Myricetin is a flavonoid found in several plants that...

    Authors: Joseph T. Ortega, Alirica I. Suárez, Maria L. Serrano, Jani Baptista, Flor H. Pujol and Hector R. Rangel

    Citation: AIDS Research and Therapy 2017 14:57

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  42. Content type: Research

    Clinicians are incorporating patient-reported outcomes in the management of HIV-infected persons co-infected with hepatitis C virus (HCV), but there are no validated inventories to monitor symptoms of patients...

    Authors: Edward R. Cachay, Craig Ballard, Bradford Colwell, Francesca Torriani, Charles Hicks and Wm. Christopher Mathews

    Citation: AIDS Research and Therapy 2017 14:56

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  43. Content type: Review

    For over three decades, HIV infection has had a tremendous impact on the lives of individuals and public health. Microbicides and vaccines studies have shown that immune activation at the genital tract is a ri...

    Authors: Julie Lajoie, Lucy Mwangi and Keith R. Fowke

    Citation: AIDS Research and Therapy 2017 14:46

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