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  1. Cryptococcal meningitis (CM) associated immune reconstitution inflammatory syndrome (CM-IRIS) is the second most common complication in HIV-infected individuals with cryptococcal meningitis, with a reported mo...

    Authors: Xiaoxu Han, Hui Liu, Yuqi Wang, Peng Wang, Xin Wang, Yunyun Yi and Xin Li
    Citation: AIDS Research and Therapy 2022 19:20
    Content type: Research Published on:

  2. Intestinal parasites and HIV/AIDS co-infection become a major public health concern in Africa. The management and care of HIV/AIDS patients is being complicated by intestinal parasitic infections. Therefore, t...

    Authors: Daniel Getacher Feleke, Abdurahaman Ali, Habtye Bisetegn and Mengaye Andualem
    Citation: AIDS Research and Therapy 2022 19:19
    Content type: Research Published on:

  3. In low income countries such as Uganda progress has been made towards achieving the United Nations AIDS programme 95-95-95 target however efforts are still impeded by pretreatment drug resistance and adverse d...

    Authors: Angella Namulindwa, John Hans Wasswa, Winnie Muyindike, Robert Tamukong and Joseph Oloro
    Citation: AIDS Research and Therapy 2022 19:18
    Content type: Research Published on:

  4. Medication adherence plays a pivotal role in achieving the desired treatment outcomes. The proportion of HIV patients on second-line antiretroviral therapy is becoming a growing public health concern. However,...

    Authors: Shambel Wedajo, Getu Degu, Amare Deribew and Fentie Ambaw
    Citation: AIDS Research and Therapy 2022 19:17
    Content type: Research Published on:

  5. Cytomegalovirus (CMV) has been linked with cardiovascular disease (CVD) in populations where some individuals are seronegative. However, effects of CMV are unclear in HIV patients who all have high levels of C...

    Authors: Ibnu A. Ariyanto, Riwanti Estiasari, Birry Karim, Ika Praseya Wijaya, Budiman Bela, Amin Soebandrio, Patricia Price and Silvia Lee
    Citation: AIDS Research and Therapy 2022 19:16
    Content type: Research Published on:

  6. Thanks to direct-acting antivirals, hepatitis C virus (HCV) infection can be cured, with similar rates in HCV-infected and HIV–HCV co-infected patients. HCV cure is likely to foster behavioral changes in psych...

    Authors: Tangui Barré, Patrick Mercié, Caroline Lions, Patrick Miailhes, David Zucman, Hugues Aumaître, Laure Esterle, Philippe Sogni, Patrizia Carrieri, Dominique Salmon-Céron and Fabienne Marcellin
    Citation: AIDS Research and Therapy 2022 19:15
    Content type: Short report Published on:

  7. The authors recently performed plastic surgeries for a small number of patients with hemophilia, HIV infection, and morphologic evidence of lipodystrophy. Because the pathophysiological mechanism of HIV-associ...

    Authors: Takanobu Mashiko, Kunihisa Tsukada, Hitomi Takada, Szu-Hsien Wu, Koji Kanayama, Rintaro Asahi, Masanori Mori, Akira Kurisaki, Shinichi Oka and Kotaro Yoshimura
    Citation: AIDS Research and Therapy 2022 19:14
    Content type: Research Published on:

  8. Patient preferences for long-acting antiretroviral therapies (LA-ART) should inform development of regimens with optimal adherence and acceptability. We describe a systematic process used to identify attribute...

    Authors: Aaron T. Brah, Douglas Barthold, Brett Hauber, Ann C. Collier, Rodney J. Y. Ho, Vincent C. Marconi, Jane M. Simoni and Susan M. Graham
    Citation: AIDS Research and Therapy 2022 19:13
    Content type: Methodology Published on:

  9. Pre-Exposure Prophylaxis (PrEP) has demonstrated efficacy in the reduction of sexually transmitted HIV infections. The prolonged use of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) co-formulatio...

    Authors: Karla Cristina Silva Petruccelli, Djane Clarys Baía-da-Silva, Fernando Val, Monica Santos Valões, Nadia Cubas-Vega, Alexandre Vilhena Silva-Neto, Vanderson Sampaio, Aline Alencar, Roberto Pecoits-Filho, Rodrigo Carvalho Moreira, Sandra Wagner Cardoso, Ronaldo I. Moreira, Iuri Costa Leite, José Valdez Madruga, Esper G. Kallas, Paulo R. Alencastro…
    Citation: AIDS Research and Therapy 2022 19:12
    Content type: Research Published on:

  10. In Nigeria, private for-profit health facilities present an opportunity to achieve the UNAIDS 95-95-95 HIV targets because of their reach and patronage. However, little is known about determinants of outcomes ...

    Authors: Muyi Aina, Zeena Yesufu, Abdulateef Salisu, Echezona Ezeanolue, Charles Mensah and Patrick Dakum
    Citation: AIDS Research and Therapy 2022 19:11
    Content type: Research Published on:

  11. Zambia recently achieved UNAIDS 90-90-90 treatment targets for HIV epidemic control; however, inpatient facilities continue to face a large burden of patients with advanced HIV disease and HIV-related mortalit...

    Authors: Nyuma Mbewe, Michael J. Vinikoor, Sombo Fwoloshi, Mundia Mwitumwa, Shabir Lakhi, Suilanji Sivile, Mallika Yavatkar, Brianna Lindsay, Kristen Stafford, Lottie Hachaambwa, Lloyd Mulenga and Cassidy W. Claassen
    Citation: AIDS Research and Therapy 2022 19:10
    Content type: Short report Published on:

  12. Estimating the population sizes of key populations(people who inject drugs, men who have sex with men, transgender persons, and commercial sex workers) is critical for understanding the overall Human Immunodef...

    Authors: Chen Xu, Fengshi Jing, Ying Lu, Yuxin Ni, Joseph Tucker, Dan Wu, Yi Zhou, Jason Ong, Qingpeng Zhang and Weiming Tang
    Citation: AIDS Research and Therapy 2022 19:9
    Content type: Review Published on:

  13. Infant antiretroviral prophylaxis has an important role in reduction of Human immune virus transmission from mother to child during the postpartum period. Male partner involvement was considered as a priority ...

    Authors: Tamirat Melis and Yohannes Fikadu
    Citation: AIDS Research and Therapy 2022 19:8
    Content type: Review Published on:

  14. Support groups for people living with the Human Immunodeficiency Virus (HIV) have continued to evolve since their emergence over two decades ago. In addition to providing HIV education and fostering psychosoci...

    Authors: Fine Mazambara, Dexter Chagwena, Tinashe Mudzviti, Samantha Sithole, Tsitsi Monera-Penduka, Charles C. Maponga and Gene D. Morse
    Citation: AIDS Research and Therapy 2022 19:7
    Content type: Short report Published on:

  15. In hospitalized people with HIV (PWH) there is an increased risk of mortality from COVID-19 among hospitalized PWH as compared to HIV-negative individuals. Evidence suggests that tocilizumab—a humanized monocl...

    Authors: Samuel J. Minkove, Grant Geiger, Josep M. Llibre, Mary W. Montgomery, Natalie E. West, Natasha M. Chida, Annukka A. R. Antar, Dima Dandachi and Ethel D. Weld
    Citation: AIDS Research and Therapy 2022 19:6
    Content type: Case report Published on:

  16. Maintaining optimal adherence and viral suppression in people living with HIV (PLWH) is essential to ensure both preventative and therapeutic benefits of antiretroviral therapy (ART). Prisoners bear a particul...

    Authors: Terefe Gone Fuge, George Tsourtos and Emma R. Miller
    Citation: AIDS Research and Therapy 2022 19:5
    Content type: Research Published on:

  17. Raltegravir (RAL) has favorable tolerability and safety profile, with few and manageable drug interactions. The use of RAL 1200 mg once daily (qd) for first-line therapy is well established. We assessed effica...

    Authors: Nolwenn Hall, Clotilde Allavena, Christine Katlama, Alexandra Jobert, Jean-Michel Molina, Eric Cua, Firouzé Bani-Sadr, Laurent Hocqueloux, Claudine Duvivier, Dominique Merrien, Hitoto Hikombo, Elisabeth André-Garnier, Aurélie Gaultier and François Raffi
    Citation: AIDS Research and Therapy 2022 19:4
    Content type: Research Published on:

  18. Data on the association of human immunodeficiency virus (HIV) infection with adverse outcomes in patients with COVID-19 are conflicting. This systematic review and meta-analysis aimed to summarize the availabl...

    Authors: Celestin Danwang, Jean Jacques Noubiap, Annie Robert and Jean Cyr Yombi
    Citation: AIDS Research and Therapy 2022 19:3
    Content type: Review Published on:

  19. We developed a personalized Monocyte-Derived Dendritic-cell Therapy (MDDCT) for HIV-infected individuals on suppressive antiretroviral treatment and evaluated HIV-specific T-cell responses.

    Authors: Marcella Vassão de Almeida Baptista, Laís Teodoro da Silva, Sadia Samer, Telma Miyuki Oshiro, Iart Luca Shytaj, Leila B. Giron, Nathalia Mantovani Pena, Nicolly Cruz, Gisele Cristina Gosuen, Paulo Roberto Abrão Ferreira, Edécio Cunha-Neto, Juliana Galinskas, Danilo Dias, Maria Cecilia Araripe Sucupira, Cesar de Almeida-Neto, Reinaldo Salomão…
    Citation: AIDS Research and Therapy 2022 19:2
    Content type: Research Published on:

  20. Retention in clinical care is important for people living with HIV (PLWH). Evidence suggests that missed clinic visits are associated with interruptions in antiretroviral therapy (ART), lower CD4 counts, virol...

    Authors: Nicole Dear, Allahna Esber, Michael Iroezindu, Emmanuel Bahemana, Hannah Kibuuka, Jonah Maswai, John Owuoth, Christina S. Polyak, Julie A. Ake and Trevor A. Crowell
    Citation: AIDS Research and Therapy 2022 19:1
    Content type: Short report Published on:

  21. In 2018, approximately 1.6 million adolescents (aged 10–19) were living with HIV worldwide, with the highest HIV prevalence found in Eswatini. Adolescents and young adults living with HIV are a vulnerable popu...

    Authors: Tara E. Ness, Vedika Agrawal, Danielle Guffey, Amanda Small, Tandzile Simelane, Sandile Dlamini, Jaime Petrus and Bhekumusa Lukhele
    Citation: AIDS Research and Therapy 2021 18:100
    Content type: Research Published on:

  22. Ethiopia, being in the Sub Saharan region of Africa, is one of the countries with a substantial burden of HIV infection. Because of the high burden of HIV and poor health care settings, HAND is prevalent as de...

    Authors: Yosef Zenebe, Baye Akele, Mulugeta W/Selassie and Mogesie Necho
    Citation: AIDS Research and Therapy 2021 18:99
    Content type: Review Published on:

  24. Adolescents are at increased risk of HIV infection compared to other age groups. There is an urgent need for strategic information that will inform programmes to reduce risk and vulnerability to HIV and revers...

    Authors: Musawenkosi Mabaso, Goitseone Maseko, Ronel Sewpaul, Inbarani Naidoo, Sean Jooste, Sinovuyo Takatshana, Tarylee Reddy, Khangelani Zuma and Nompumelelo Zungu
    Citation: AIDS Research and Therapy 2021 18:97
    Content type: Research Published on:

  25. Late presentation to HIV/AIDS care presents serious health concerns, like increased transmission and high healthcare costs, increased mortality, early development of opportunistic infection, increased risk of ...

    Authors: Chengqing Sun, Jianjun Li, Xiaoyan Liu, Zhi Zhang, Tao Qiu, Haiyang Hu, You Wang and Gengfeng Fu
    Citation: AIDS Research and Therapy 2021 18:96
    Content type: Review Published on:

  26. AIDS as a human crisis may lead to devastating psychological trauma and stress for patients. Therefore, it is necessary to study different aspects of their lives for better support and care. Accordingly, this ...

    Authors: Behzad Imani, Shirdel Zandi, Salman khazaei and Mohamad Mirzaei
    Citation: AIDS Research and Therapy 2021 18:95
    Content type: Research Published on:

  27. Tenofovir disoproxil fumarate (TDF) has a strong antiviral effect, but TDF is known to cause renal dysfunction. Therefore, we are investigating preventing renal dysfunction by replacing TDF with tenofovir alaf...

    Authors: Kensuke Abe, Taku Obara, Satomi Kamio, Asahi Kondo, Junji Imamura, Tatsuya Goto, Toshihiro Ito, Hiroshi Sato and Nobuyuki Takahashi
    Citation: AIDS Research and Therapy 2021 18:94
    Content type: Research Published on:

  28. Anti-retroviral therapy regimen discontinuations become a big challenge and cause diminishing the clinical and immunological benefit of treatment in Ethiopia. It reduces both the duration and the chance of vir...

    Authors: Tewodros Getnet Amera, Kassawmar Angaw Bogale and Yibekal Manaye Tefera
    Citation: AIDS Research and Therapy 2021 18:93
    Content type: Research Published on:

  29. This study aims to evaluate the safety of inactivated COVID-19 vaccine among adult people living with HIV (PLWH). In total, 259 PLWH who received at least one dose of inactivated COVID-19 vaccine were enrolled...

    Authors: Songjie Wu, Yubin Zhang, Fangzhao Ming, Shi Zou, Mengmeng Wu, Wei Guo, Weiming Tang and Ke Liang
    Citation: AIDS Research and Therapy 2021 18:92
    Content type: Short Report Published on:

  30. Adolescents are lagging behind in the “third 95” objective of the Joint United Nations Program on HIV/AIDS requiring 95% of individuals on antiretroviral therapy (ART) to have viral load (VL) suppression. This...

    Authors: Joel Maena, Aduragbemi Banke-Thomas, Nelson Mukiza, Cynthia Ndikuno Kuteesa, Ronald Makanga Kakumba, Hajira Kataike, Samuel Kizito, Juliet Allen Babirye and Rita Nakalega
    Citation: AIDS Research and Therapy 2021 18:91
    Content type: Research Published on:

  31. Disseminated Mycobacterium avium complex infection is an important indicator of acquired immunodeficiency syndrome (AIDS) in patients with advanced human immunodeficiency virus (HIV) infection. Effective antiretr...

    Authors: Keiji Konishi, Hidenori Nakagawa, Akio Nakahira, Takahiro Okuno, Takeshi Inoue and Michinori Shirano
    Citation: AIDS Research and Therapy 2021 18:90
    Content type: Case Report Published on:

  32. Increased availability of HIV care over the past decade has dramatically reduced morbidity and mortality among people living with HIV (PLWH) in sub-Saharan Africa. However, perceived and experienced barriers t...

    Authors: Nancy Somi, Nicole Dear, Domonique Reed, Ajay Parikh, Anange Lwilla, Emmanuel Bahemana, Samoel Khamadi, Michael Iroezindu, Hannah Kibuuka, Jonah Maswai, Trevor A. Crowell, John Owuoth, Lucas Maganga, Christina Polyak, Julie Ake and Allahna Esber
    Citation: AIDS Research and Therapy 2021 18:89
    Content type: Research Published on:

  33. World Health Organization (WHO) reports that people who indulge in risky behaviours such as penile-anal sex, unprotected intercourse, multiple sex partners, and alcohol and illicit drugs are at risk of HIV/AID...

    Authors: Olawale Durosinmi-Etti, Emmanuel Kelechi Nwala, Funke Oki, Akudo Ikpeazu, Emmanuel Godwin, Paul Umoh, Arome Shaibu, Alex Ogundipe and Abiye Kalaiwo
    Citation: AIDS Research and Therapy 2021 18:88
    Content type: Research Published on:

  34. Events associated with the COVID-19 pandemic, such as physical distancing, closure of community services, postponement of health appointments, and loss of employment can lead to social isolation, financial unc...

    Authors: Kelly K. O’Brien, Ahmed M. Bayoumi, Soo Chan Carusone, Aileen M. Davis, Rachel Aubry, Lisa Avery, Patricia Solomon, Kristine M. Erlandson, Colm Bergin, Richard Harding, Darren A. Brown, Jaime H. Vera and Steven E. Hanna
    Citation: AIDS Research and Therapy 2021 18:87
    Content type: Research Published on:

  35. Thoracic actinomycosis is an uncommon, chronic, and progressive infection, especially in patients with HIV. We report a case of thoracic actinomycosis presenting as an isolated pleural effusion in a patient wi...

    Authors: Jung Wan Park, Yon Hee Kim, Eunjung Lee, Se Yoon Park and Tae Hyong Kim
    Citation: AIDS Research and Therapy 2021 18:86
    Content type: Case Report Published on:

  36. Programmes that merge management of Human Immunodeficiency Virus (HIV) and tuberculosis (TB) aim to improve HIV/TB co-infected patients’ access to comprehensive treatment. However, several reports from sub-Sah...

    Authors: Benjamin Momo Kadia, Christian Akem Dimala, Noah T. Fongwen and Adrian D. Smith
    Citation: AIDS Research and Therapy 2021 18:85
    Content type: Research Published on:

  37. In 2007–2012 the Mexican government launched the National HIV program and there was a major change in HIV policies implemented in 2013–2018, when efforts focused on prevention, increase in early diagnosis and ...

    Authors: Amilcar Azamar-Alonso, Sergio A. Bautista-Arredondo, Fiona Smaill, Lawrence Mbuagbaw, Andrew P. Costa and Jean-Eric Tarride
    Citation: AIDS Research and Therapy 2021 18:84
    Content type: Research Published on:

  38. Accelerated atherosclerosis in older HIV-infected patients has been attributed to persistent immune activation and high burden cytomegalovirus (CMV), as demonstrated in transplant recipients and the general po...

    Authors: Ika Prasetya Wijaya, Birry Karim, Mohamad Syahrir Azizi, Ibnu Ariyanto, Arif Mansjoer, Evy Yunihastuti, Kuntjoro Harimurti, Idrus Alwi, Silvia Lee and Patricia Price
    Citation: AIDS Research and Therapy 2021 18:83
    Content type: Short Report Published on:

  39. To evaluate the effect of reconstruction and repair, using a mini-plate and bone graft for HIV -positive patients with giant cell tumor of long bone.

    Authors: Biao Xu, Rui Ma, Wen-sheng Zhang, Qiang Zhang, Chang-song Zhao and Jie Wang
    Citation: AIDS Research and Therapy 2021 18:82
    Content type: Research Published on:

  40. Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this s...

    Authors: Ludentz Dorcélus, Joseph Bernard Jr., Constant Georgery and Clerveau Vanessa
    Citation: AIDS Research and Therapy 2021 18:81
    Content type: Research Published on:

  41. The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown...

    Authors: Z. C. Lim, G. S. Hoo, J. H. Ang, C. B. Teng, L. W. Ang, C. C. Lee, Y. S. Leo, H. L. Law, O. T. Ng and C. S. Wong
    Citation: AIDS Research and Therapy 2021 18:80
    Content type: Research Published on:

  42. Viral suppression prevents HIV transmission and disease progression, but socio-economic and clinical factors can hinder the goal of suppression. We evaluated factors associated with viral non suppression (VNS)...

    Authors: Dean W. Ortíz, Olivia Roberts-Sano, Hugo E. Marroquin, Lindsey Larson, Katherine B. Franco, Andrej Spec, Johanna R. Melendez, Rodolfo Pinzón, Ana J. Samayoa, Carlos Mejia-Chew and Jane A. O´Halloran
    Citation: AIDS Research and Therapy 2021 18:79
    Content type: Research Published on:

  43. Symptoms of primary HIV infection, including fever, rash, and headache, are nonspecific and are often described as flu-like. COVID-19 vaccination side effects, such as fever, which occur in up to 10% of people...

    Authors: Julian Triebelhorn, Stefanie Haschka, Felix Hesse, Johanna Erber, Simon Weidlich, Marcel Lee, Dieter Hoffmann, Josef Eberle and Christoph D. Spinner
    Citation: AIDS Research and Therapy 2021 18:78
    Content type: Case Report Published on:

  44. Targeting RNA is a promising yet underdeveloped modality for the selective killing of cells infected with HIV-1. The secretory ribonucleases (RNases) found in vertebrates have cytotoxic ribonucleolytic activit...

    Authors: Ian W. Windsor, Dawn M. Dudley, David H. O’Connor and Ronald T. Raines
    Citation: AIDS Research and Therapy 2021 18:77
    Content type: Research Published on:

  45. AIDS-related primary central nervous system lymphoma (AR-PCNSL) is an AIDS-defining disease that usually occurs when the CD4 count is less than 50 cells/μl. The frequency of the disease has substantially decre...

    Authors: Pieter-Jan Gijs and Olivier Clerc
    Citation: AIDS Research and Therapy 2021 18:76
    Content type: Case Report Published on:

  46. An increasing number of HIV cure trials involve combining multiple potentially curative interventions. Until now, considerations for designing and implementing complex combination HIV cure trials have not been...

    Authors: Karine Dubé, John Kanazawa, Lynda Dee, Jeff Taylor, John A. Sauceda, Sara Gianella, Davey Smith, Steven G. Deeks and Michael J. Peluso
    Citation: AIDS Research and Therapy 2021 18:75
    Content type: Research Published on:

  47. Introduction of tenofovir (TDF) plus lamivudine (3TC) and dolutegravir (DTG) in first- and second-line HIV treatment regimens in South Africa warrants characterization of acquired HIV-1 drug resistance (ADR) m...

    Authors: Benjamin Chimukangara, Richard J. Lessells, Lavanya Singh, Indra Grigalionyte, Nonhlanhla Yende-Zuma, Rochelle Adams, Halima Dawood, Linda Dlamini, Sibonisile Buthelezi, Sheldon Chetty, Karidia Diallo, Wayne A. Duffus, Mary Mogashoa, Melissa B. Hagen, Jennifer Giandhari, Tulio de Oliveira…
    Citation: AIDS Research and Therapy 2021 18:74
    Content type: Research Published on:

  48. A 73-year-old male patient who had a history of Human Immunodeficiency Virus (HIV) infection for over 20 years was diagnosed with SARS-CoV-2 infection.

    Authors: Pedro Vieira Bertozzi, Amanda de Oliveira Vicente, Amanda Siqueira Pereira, Joao Pedro Espinha de Sant’Ana, Rafaela Braga Cabrera Mano, Luciana Souza Jorge and Rodrigo Afonso da Silva Sardenberg
    Citation: AIDS Research and Therapy 2021 18:73
    Content type: Case Report Published on:

  49. The growing burden of the HIV and non-communicable disease (NCD) syndemic in Sub- Saharan Africa has necessitated introduction of integrated models of care in order to leverage existing HIV care infrastructure...

    Authors: Blessings Gausi, Natacha Berkowitz, Nisha Jacob and Tolu Oni
    Citation: AIDS Research and Therapy 2021 18:72
    Content type: Research Published on:

  50. The current standard of care is to start antiretroviral therapy in all patients diagnosed with HIV-1, as for HIV-2 current DHHS guideline suggests ART for HIV-2 as soon as diagnosis is established, although th...

    Authors: Margarida Cardoso, Joana Vasconcelos, Teresa Baptista, Isabel Diogo, Fátima Gonçalves, Kamal Mansinho and Perpétua Gomes
    Citation: AIDS Research and Therapy 2021 18:69
    Content type: Case Report Published on:

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AIDS Research and Therapy

ISSN: 1742-6405

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