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  1. Tuberculosis preventive therapy is vital in caring for HIV-positive individuals, as it prevents the progression from latent tuberculosis infection to tuberculosis disease. The aim of the study is to assess the...

    Authors: Alebachew Zewdu Tegegnework, Muluken Tessema Aemiro, Awraris Hailu Bilchut, Abinet Dagnaw Mekuria and Sisay Shewasinad Yehualashet
    Citation: AIDS Research and Therapy 2024 21:44
    Content type: Research Published on:

  2. Despite remarkable progress, HIV’s influence on global health remains firm, demanding continued attention. Understanding the effectiveness of third-line antiretroviral therapy in individuals who do not respond...

    Authors: Tegene Atamenta kitaw, Biruk Beletew Abate, Gizachew Yilak, Befkad Derese Tilahun, Abebe Merchaw Faris, Getachew Tesfaw Walle and Ribka Nigatu Haile
    Citation: AIDS Research and Therapy 2024 21:43
    Content type: Review Published on:

  3. Ethiopia’s viral suppression rate was less than 90% by 2020, and more than 10% of adult clients on ART in Woliso Town were unsuppressed at the end of March 2022. This study aims to identify determinants of vir...

    Authors: Worku Gidisa Ayana, Mulatu Ayana Hordofa and Abebe Dechasa Yadeta
    Citation: AIDS Research and Therapy 2024 21:42
    Content type: Research Published on:

  4. The World Health Organisation has implemented multiple HIV prevention policies and strived to achieve the 90-90-90 goal by 2020, achieving the 95-95-95 goal by 2030, which refers to 95% of patients living with...

    Authors: Hsun-Yin Huang, Yu-Ching Huang, Hsiu-Yun Lo, Pei-Chun Chan and Chia-Chi Lee
    Citation: AIDS Research and Therapy 2024 21:41
    Content type: Research Published on:

  5. Scholars recommend providing migrants living with HIV (MLWH) with free treatment, rapidly, once linked to care to optimize their HIV-related experiences and health outcomes. Quantitative evaluations of patient...

    Authors: Anish K. Arora, Serge Vicente, Kim Engler, David Lessard, Edmundo Huerta, Joel Ishak, Nadine Kronfli, Jean-Pierre Routy, Joseph Cox, Benoit Lemire, Marina Klein, Alexandra de Pokomandy, Lina Del Balso, Giada Sebastiani, Isabelle Vedel, Amélie Quesnel-Vallée…
    Citation: AIDS Research and Therapy 2024 21:40
    Content type: Research Published on:

  6. Mother-to-child transmission (MTCT) of the human immunodeficiency virus (HIV) remains a major public health challenge in Ethiopia. The objective of this review was to assess the pooled magnitude of MTCT of HIV...

    Authors: Wolde Facha, Takele Tadesse, Eskinder Wolka and Ayalew Astatkie
    Citation: AIDS Research and Therapy 2024 21:39
    Content type: Research Published on:

  7. People with HIV/AIDS (PWHA) have 7–36 times greater risk for completed suicide associated with depression symptoms compared to general population. However, no study has sufficiently analyzed the mediating or m...

    Authors: Anualitha Uwiringiyimana, Japhet Niyonsenga, Kethina Gaju Lisette, Athanasie Bugenimana, Jean Mutabaruka and Augustin Nshimiyimana
    Citation: AIDS Research and Therapy 2024 21:38
    Content type: Research Published on:

  8. Despite the widespread use of pre-exposure prophylaxis (PrEP) in preventing human immunodeficiency virus (HIV) transmission, scant information on HIV drug resistance mutations (DRMs) has been gathered over the...

    Authors: Brian Eka Rachman, Siti Qamariyah Khairunisa, Citrawati Dyah Kencono Wungu, Tri Pudy Asmarawati, Musofa Rusli, Bramantono, M. Vitanata Arfijanto, Usman Hadi, Masanori Kameoka and Nasronudin
    Citation: AIDS Research and Therapy 2024 21:37
    Content type: Research Published on:

  9. The association between HIV infection and increased cardiometabolic risk, attributed to chronic inflammation in people living with HIV (PLWH) and/or antiretroviral therapy (ART) effects, has been inconsistent....

    Authors: Peter Vanes Ebasone, Anastase Dzudie, Nasheeta Peer, Donald Hoover, Qiuhu Shi, Hae-Young Kim, Ellen Brazier, Rogers Ajeh, Marcel Yotebieng, Denis Nash, Kathryn Anastos and Andre Pascal Kengne
    Citation: AIDS Research and Therapy 2024 21:36
    Content type: Research Published on:

  10. Despite the decreased incidence of the human immunodeficiency virus (HIV) in Tanzania, the number of adolescents living with HIV is increasing. This study aimed to describe factors independently associated wit...

    Authors: Stella Emmanuel Mushy, Expeditho Mtisi, Simon Mkawe, Eric Mboggo, John Ndega, Khadija I. Yahya-Malima, Denice Kamugunya, Edwin Samuel Kilimba, Boniface S. Mlay, Aisa Muya and Frida Ngalesoni
    Citation: AIDS Research and Therapy 2024 21:35
    Content type: Research Published on:

  11. Peritoneal dialysis (PD) is an effective renal replacement modality in people with HIV (PWH) with end-stage kidney disease (ESKD), particularly those with residual kidney function. Data on pharmacokinetics (PK...

    Authors: Sandra Abdul Massih, Mohamed G. Atta, Chloe L. Thio, Jeffrey A. Tornheim, Edward J. Fuchs, Rahul P. Bakshi, Mark A. Marzinke, Craig W. Hendrix and Ethel D. Weld
    Citation: AIDS Research and Therapy 2024 21:34
    Content type: Case Report Published on:

  12. HIV early infant diagnosis (HEID) at the centralized laboratory faces many challenges that impact the cascade of timely HEID. Point of Care (PoC) HEID has shown to reduce test turnaround times, allow for task ...

    Authors: Siriel Boniface, Anange Lwilla, Hellen Mahiga, Doreen Pamba, Otto Geisenberger, John France, Rebecca Mokeha, Lilian Njovu, Abisai Kisinda, Nyanda Elias Ntinginya, Michael Hoelscher, Arne Kroidl and Issa Sabi
    Citation: AIDS Research and Therapy 2024 21:33
    Content type: Research Published on:

  13. Intestinal parasitic infections (IP) are a major source of morbidity in people living with Human immunodeficiency virus (HIV), particularly in resource-limited settings, mostly as a result of high viral load. ...

    Authors: Mengistu Endalamaw, Abel Alemneh, Gashaw Azanaw Amare, Abebe Fenta and Habtamu Belew
    Citation: AIDS Research and Therapy 2024 21:32
    Content type: Research Published on:

  14. Uganda Ministry of Health (MOH) recommends a first HIV DNA-PCR test at 4–6 weeks for early infant diagnosis (EID) of HIV-exposed infants (HEI) and immediate return of results. WHO recommends initiating antiret...

    Authors: Stella M. Migamba, Tamara Nsubuga Nyombi, Edirisa Juniour Nsubuga, Andrew Kwiringira, Augustina Delaney, Steven Ndugwa Kabwama, Mary Nakafeero, Benon Kwesiga, Daniel Kadobera, Phoebe Monalisa-Mayambala, Lilian Bulage, Alex Riolexus Ario and Julie R. Harris
    Citation: AIDS Research and Therapy 2024 21:31
    Content type: Research Published on:

  16. The COVID-19 pandemic has put the provision of health services globally at risk. In Sub-Saharan Africa, it had a major impact on HIV services. However, there is a lack of data on the post-pandemic period. This...

    Authors: Roberto Benoni, Francesco Cavallin, Virginia Casigliani, Annachiara Zin, Dara Giannini, Izilda Chaguruca, Vasco Cinturao, Fernando Chinene, Giulia Brigadoi, Daniele Donà, Giovanni Putoto and Carlo Giaquinto
    Citation: AIDS Research and Therapy 2024 21:29
    Content type: Research Published on:

  17. Self-management is the most important strategy to improve quality of life in patients with a chronic disease. Despite the increasing number of people living with HIV (PLWH) in low-income countries, very little...

    Authors: Tegene Legese Dadi, Yadessa Tegene, Nienke Vollebregt, Girmay Medhin and Mark Spigt
    Citation: AIDS Research and Therapy 2024 21:28
    Content type: Research Published on:

  18. Human genetic contribution to HIV progression remains inadequately explained. The type 1 interferon (IFN) pathway is important for host control of HIV and variation in type 1 IFN genes may contribute to diseas...

    Authors: Sara Bohnstedt Mørup, Preston Leung, Cavan Reilly, Brad T. Sherman, Weizhong Chang, Maja Milojevic, Ana Milinkovic, Angelike Liappis, Line Borgwardt, Kathy Petoumenos, Roger Paredes, Shweta S. Mistry, Cameron R. MacPherson, Jens Lundgren, Marie Helleberg, Joanne Reekie…
    Citation: AIDS Research and Therapy 2024 21:27
    Content type: Research Published on:

  19. Authors: Munyaradzi Mapingure, Innocent Chingombe, Tafadzwa Dzinamarira, Brian Moyo, Chesterfield Samba, Delight Murigo, Owen Mugurungi, Elliot Mbunge, Rutendo Birri Makota, Grant Murewanhema and Godfrey Musuka
    Citation: AIDS Research and Therapy 2024 21:26
    Content type: Correction Published on:

    The original article was published in AIDS Research and Therapy 2024 21:18

  20. Bacillus Calmette-Guérin (BCG) reactions are the most common cause of immune reconstitution inflammatory syndrome (IRIS) in HIV-positive infants who initiate antiretroviral therapy (ART). There is limited evid...

    Authors: Percina Machava, Winete Joaquim, Joseph Borrell, Shannon Richardson, Uneisse Cassia, Muhammad Sidat, Alice Maieca, Cláudia Massitela, Yara Quelhas, Cafrina Mucuila, Beatriz Elias, Massada da Rocha, H. Simon Schaaf and W. Chris Buck
    Citation: AIDS Research and Therapy 2024 21:25
    Content type: Case Report Published on:

  21. Erythema multiforme (EM) is an immune-mediated mucocutaneous condition characterized by hypersensitivity reactions to antigenic stimuli from infectious agents and certain drugs. The most commonly implicated in...

    Authors: Shumani Charlotte Manenzhe, Razia Abdool Gafaar Khammissa, Sindisiwe Londiwe Shangase and Mia Michaela Beetge
    Citation: AIDS Research and Therapy 2024 21:24
    Content type: Review Published on:

  22. Dolutegravir (DTG)-based antiretroviral therapy (ART) is currently the preferred first-line treatment for persons living with HIV (PLHIV) including children and adolescents in many low- and middle-income count...

    Authors: Irene Nakatudde, Elizabeth Katana, Eva Laker Agnes Odongpiny, Esther Alice Nalugga, Barbara Castelnuovo, Mary Glenn Fowler and Philippa Musoke
    Citation: AIDS Research and Therapy 2024 21:23
    Content type: Research Published on:

  23. Initiation of ART among people living with HIV (PLWH) having a CD4 count ≤ 350cells/µl, produces poor immunological recovery, putting them at a high risk of opportunistic infections. To mitigate this, PLWH on ...

    Authors: Silvano S. Twinomujuni, Esther C Atukunda, Jackson K. Mukonzo, Musinguzi Nicholas, Felicitas Roelofsen and Patrick E. Ogwang
    Citation: AIDS Research and Therapy 2024 21:22
    Content type: Brief Report Published on:

  24. Maintaining people living with HIV (PLWHIV) in clinical care is a global priority. In the Metro Detroit area of Michigan, approximately 30% of PLWHIV are out of care. To re-engage lost-to-follow-up patients, W...

    Authors: L. V. Bonadonna, E. Guerrero, T. McClendon, S. Union, D. Kabbani, D. Wittmann, J. Cohn and J. Veltman
    Citation: AIDS Research and Therapy 2024 21:21
    Content type: Research Published on:

  25. HIV testing remains an important tool in identifying people living with HIV/AIDS (PLWHA). An early diagnosis of HIV can lead to a prolonged life expectancy if treatment is initiated promptly. Indicator conditi...

    Authors: Lina Martina Würfel, Anja Potthoff, Sandeep Nambiar and Adriane Skaletz-Rorowski
    Citation: AIDS Research and Therapy 2024 21:20
    Content type: Case Report Published on:

  26. Syphilis is an infection caused by the bacteria Treponema pallidum. It is mainly transmitted through oral, vaginal and anal sex, in pregnancy and through blood transfusion. Syphilis develops in primary, secondary...

    Authors: Sukoluhle Khumalo, Yves Mafulu, Victor Williams, Normusa Musarapasi, Samson Haumba and Nkululeko Dube
    Citation: AIDS Research and Therapy 2024 21:19
    Content type: Case Report Published on:

  27. We conducted secondary data analysis using a biobehavioral survey dataset of 1538 MSM from Zimbabwe. Survey participants were screened for the four symptoms suggestive of tuberculosis infection using the WHO T...

    Authors: Munyaradzi Mapingure, Innocent Chingombe, Tafadzwa Dzinamarira, Brian Moyo, Chesterfield Samba, Delight Murigo, Owen Mugurungi, Elliot Mbunge, Rutendo Birri Makota, Grant Murewanhema and Godfrey Musuka
    Citation: AIDS Research and Therapy 2024 21:18
    Content type: Brief Communication Published on:

    The Correction to this article has been published in AIDS Research and Therapy 2024 21:26

  28. As the population of people with HIV ages, concerns over managing age-related comorbidities, polypharmacy, immune recovery, and drug-drug interactions while maintaining viral suppression have arisen. We presen...

    Authors: Sharon Walmsley, Don E. Smith, Miguel Górgolas, Pedro E. Cahn, Thomas Lutz, Karine Lacombe, Princy N. Kumar, Brian Wynne, Richard Grove, Gilda Bontempo, Riya Moodley, Chinyere Okoli, Michelle Kisare, Bryn Jones, Andrew Clark and Mounir Ait-Khaled
    Citation: AIDS Research and Therapy 2024 21:17
    Content type: Research Published on:

  29. Young female sex workers (YFSWs) face a higher risk of HIV infection compared to older workers, but there is a lack of comprehensive data on their sexual practices and HIV infection risks, which may present un...

    Authors: Olivier Mukuku, Yannick Nkiambi Kiakuvue, Georges Yumba Numbi, Bienvenu Mukuku Ruhindiza, Christian Kakisingi, Claude Mulumba Mwamba and Joe Kabongo Katabwa
    Citation: AIDS Research and Therapy 2024 21:16
    Content type: Research Published on:

  30. Antiretroviral Therapy (ART) is pivotal in extending the lives of people living with HIV (PLWH) and minimizing transmission. Rapid ART initiation, defined as commencing ART within seven days of HIV diagnosis, ...

    Authors: Cheng Chen, Hao Chen, Lingli Wu, Qin Gong and Jingchun He
    Citation: AIDS Research and Therapy 2024 21:15
    Content type: Research Published on:

  31. HIV partner disclosure rates remain low among pregnant women living with HIV in many African countries despite potential benefits for women and their families. Partner disclosure can trigger negative responses...

    Authors: Adelline Twimukye, Yussif Alhassan, Beate Ringwald, Thokozile Malaba, Landon Myer, Catriona Waitt, Mohammed Lamorde, Helen Reynolds, Saye Khoo and Miriam Taegtmeyer
    Citation: AIDS Research and Therapy 2024 21:14
    Content type: Research Published on:

  32. Cardiovascular disease (CVD) remains a leading cause of death in people living with HIV. Myocardial fibrosis is well-described in HIV infection acquired in adulthood. We evaluate the burden of fibrosis by card...

    Authors: Jason L. Williams, Frances Hung, Elizabeth Jenista, Piers Barker, Hrishikesh Chakraborty, Raymond Kim, Andrew W. McCrary, Svati H. Shah, Nathan Thielman and Gerald S. Bloomfield
    Citation: AIDS Research and Therapy 2024 21:13
    Content type: Brief Report Published on:

  33. Increased incidence of lifestyle diseases as side-effects of antiretroviral therapy (ART) have been reported in people living with HIV (PLWH). Few studies have evaluated obesity and hidden obesity in Japanese ...

    Authors: K. Konishi, H. Nakagawa, T. Asaoka, Y. Kasamatsu, T. Goto and M. Shirano
    Citation: AIDS Research and Therapy 2024 21:12
    Content type: Research Published on:

  34. Maternal transmission of human immunodeficiency virus (HIV) commonly occurs from mother to child during pregnancy, delivery, and breastfeeding which accounts for almost all the new HIV infections among childre...

    Authors: Agani Afaya and Aloysia Ispriantari
    Citation: AIDS Research and Therapy 2024 21:11
    Content type: Research Published on:

  35. Acquired Immune Deficiency Syndrome (AIDS) is a highly dangerous infectious disease caused by the Human Immunodeficiency Virus (HIV), a virus that attacks the human immune system. To explore the correlation be...

    Authors: Pengfei Meng, Guichun Zhang, Xiuxia Ma, Xue Ding, Xiyuan Song, Shuyuan Dang, Ruihan Yang and Liran Xu
    Citation: AIDS Research and Therapy 2024 21:10
    Content type: Research Published on:

  36. The Integrated Bio-Behavioural Surveillance Survey of 2022–2023 among key populations report from Zanzibar has been released. The prevalence of HIV is estimated to be 21.1%, 11.4%, and 9.3% among Female Sex Wo...

    Authors: Mansour Maulid Mshenga and Weiming Tang
    Citation: AIDS Research and Therapy 2024 21:9
    Content type: Brief Communication Published on:

  37. Studies on antiretroviral therapy (ART) in children living with HIV (CLHIV) are limited due to the small population and low accession rate of ART.

    Authors: Ting Zeng, Xin Chen, Xiao-Yi Zhang, Chao-Xian Lian, Rong-Rong Yang, Li-Ling Yu, Xiao-Kang Liao, Dan-Dan Huang, Yu-Ning Zhang and Hong-Min Cao
    Citation: AIDS Research and Therapy 2024 21:8
    Content type: Research Published on:

  38. Availability of anti-retroviral treatment has changed HIV in to a manageable chronic disease, making effective self-management essential. However, only a few studies in low- and middle-income countries (LMICs)...

    Authors: Tegene Legese Dadi, Anja M. C. Wiemers, Yadessa Tegene, Girmay Medhin and Mark Spigt
    Citation: AIDS Research and Therapy 2024 21:7
    Content type: Review Published on:

  39. Antiretroviral therapy client satisfaction is a significant tool that enables to strengthen the quality of life of the clients. The study aimed to assess the satisfaction of clients with antiretroviral therapy...

    Authors: Bayisa Abdissa, Rahel Abdissa, Jiregna Derega and Senahara Korsa Wake
    Citation: AIDS Research and Therapy 2024 21:6
    Content type: Research Published on:

  40. Human Immunodeficiency Virus (HIV) infection remains a public health concern in many countries. The increased life expectancy in the post-Antiretroviral Therapy (ART) era has led to an increased risk of cardiovas...

    Authors: Mawulorm K. I. Denu, Ritika Revoori, Maame Araba E. Buadu, Oluwakemi Oladele and Kofi Poku Berko
    Citation: AIDS Research and Therapy 2024 21:5
    Content type: Research Published on:

  41. There is limited data on dolutegravir (DTG)-associated weight gain from settings with a dual burden of HIV and overnutrition.

    Authors: Didier M. Mukuna, Tom Decroo and Clara M. Nyapokoto
    Citation: AIDS Research and Therapy 2024 21:4
    Content type: Research Published on:

  42. Malakoplakia is a rare chronic granulomatous disease characterized by the presence of Michaelis-Gutmann bodies (MGBs) within histiocytic aggregates. It predominantly affects immunocompromised individuals, incl...

    Authors: Mohammed Alsaeed, Mohamed Mursi, Nazik Eltayeb, Hadi Kuriry, Salafa Albaghli and Yasir Alrusayni
    Citation: AIDS Research and Therapy 2024 21:3
    Content type: Case Report Published on:

  43. Empyema caused by Streptococcus constellatus (S. constellatus) is rare in patients with HIV. To analyze the clinical data of a patient living with HIV (PLHIV), who got empyema caused by S. constellatus, invest...

    Authors: Hong-Hong Yang, Mei Li, Qing Yu, Qian Liu and Min Liu
    Citation: AIDS Research and Therapy 2024 21:2
    Content type: Case Report Published on:

  44. We assessed whether the impact of cabotegravir plus rilpivirine on inflammation reduction differs from that of oral antiretrovirals, using real-world data. Inflammatory biomarkers and lipid profiles were follo...

    Authors: Eisuke Adachi, Makoto Saito, Amato Otani, Michiko Koga and Hiroshi Yotsuyanagi
    Citation: AIDS Research and Therapy 2024 21:1
    Content type: Research Published on:

  45. Low-adherence to Anti-retroviral therapy (ART) negatively affects the clinical, immunological, and virologic outcomes of patients. Adherence is the most important factor in determining Antiretroviral Therapy (...

    Authors: Yihenew Zurbachew, Desta Hiko, Girma Bacha and Hailu Merga
    Citation: AIDS Research and Therapy 2023 20:91
    Content type: Research Published on:

  46. Intensive adherence counseling (IAC) is the global standard of care for people living with human immunodeficiency virus (PLHIV) who have unsuppressed VL after ≥ 6 months of first-line anti-retroviral therapy (...

    Authors: Jonathan Izudi, Barbara Castelnuovo, Rachel King and Adithya Cattamanchi
    Citation: AIDS Research and Therapy 2023 20:90
    Content type: Brief Report Published on:

  47. Major depression is the most common neuropsychiatric disorder among people living with HIV (PLWH) and is predictive of high morbidity and mortality among them. This study estimated the prevalence and explored ...

    Authors: Waheed Adeola Adedeji, Qing Ma, Abiodun Muhammed Raji, Raymond Cha, Olaniran Mudasiru Rasaki, Alan Hutson, Babafemi O. Taiwo, Man E. Charurat, Oyindamola B. Yusuf, Fatai Adewale Fehintola, Oye Gureje and Gene D. Morse
    Citation: AIDS Research and Therapy 2023 20:89
    Content type: Research Published on:

  48. In spite of the global decreasing mortality associated with HIV, adolescents living with HIV (ADLHIV) in sub-Saharan Africa still experience about 50% mortality rate. We sought to evaluate survival rates and d...

    Authors: Nicholas Tendongfor, Joseph Fokam, Collins Ambe Chenwi, Fabrice Léo Tamhouo Nwabo, Armanda Nangmo, Njume Debimeh, Suzie Tetang Ndiang Moyo, Marie Patrice Halle, Anne-Esther Njom-Nlend, Paul Koki Ndombo and Alexis Ndjolo
    Citation: AIDS Research and Therapy 2023 20:88
    Content type: Research Published on:

  49. Surging HIV prevalence across countries of Central and Eastern Europe (CEE) is largely a result of poor HIV care engagement and a lack of comprehensive support for key populations. This is fostered by widespre...

    Authors: Ana-Maria Schweitzer, Arian Dišković, Veronica Krongauz, Julie Newman, Janez Tomažič and Nina Yancheva
    Citation: AIDS Research and Therapy 2023 20:87
    Content type: Review Published on:

  50. In 2016, the Canada-International HIV and Rehabilitation Research Collaborative established a framework of research priorities in HIV, aging and rehabilitation. Our aim was to review and identify any new emerg...

    Authors: Kelly K. O’Brien, Francisco Ibáñez-Carrasco, Kelly Birtwell, Graeme Donald, Darren A. Brown, Andrew D. Eaton, Bakita Kasadha, Emma Stanmore, Natalie St. Clair-Sullivan, Liam Townsend, Jaime H. Vera and Patricia Solomon
    Citation: AIDS Research and Therapy 2023 20:86
    Content type: Brief Report Published on:

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AIDS Research and Therapy

ISSN: 1742-6405

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