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AIDS Research and Therapy

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  1. Content type: Research

    We hypothesized that frailty acts as a measure of health outcomes in the context of LT. The aim of this study was to explore frailty index across LT, as a measure of morbidity and mortality. This was a retrosp...

    Authors: Giovanni Guaraldi, Giovanni Dolci, Stefano Zona, Giuseppe Tarantino, Valentina Serra, Roberto Ballarin, Erica Franceschini, Mauro Codeluppi, Thomas D. Brothers, Cristina Mussini and Fabrizio Di Benedetto

    Citation: AIDS Research and Therapy 2017 14:37

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  2. Content type: Research

    Combination antiretroviral therapy (cART) has significantly reduced HIV morbidity and mortality in both developed and developing countries. However, the sustainability of cART may be compromised by the emergen...

    Authors: Elizabeth M. Etta, Lufuno Mavhandu, Cecile Manhaeve, Keanan McGonigle, Patrick Jackson, David Rekosh, Marie-Louise Hammarskjold, Pascal O. Bessong and Denis M. Tebit

    Citation: AIDS Research and Therapy 2017 14:36

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  3. Content type: Research

    Safety and immunogenicity of the quadrivalent human papillomavirus (qHPV) vaccine were evaluated in HIV-positive Spanish MSM. The prevalence of High Squamous Intraepithelial Lesions (HSIL) and genotypes of hig...

    Authors: Carmen Hidalgo-Tenorio, Jessica Ramírez-Taboada, Concepción Gil-Anguita, Javier Esquivias, Mohamed Omar-Mohamed-Balgahata, Antonio SamPedro, Miguel Lopez-Ruz and Juan Pasquau

    Citation: AIDS Research and Therapy 2017 14:34

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  4. Content type: Research

    Preparing adolescents for transition into adult care and supporting their acquisition of self-health care management skills is a critical determinant of their post-transition HIV care outcomes. However, there ...

    Authors: Siyan Yi, Chanrith Ngin, Khuondyla Pal, Vohith Khol, Sovannary Tuot, Sokunmealiny Sau, Pheak Chhoun, Gitau Mburu, Sok Chamreun Choub, Kolab Chhim and Penhsun Ly

    Citation: AIDS Research and Therapy 2017 14:33

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  5. Content type: Review

    Current treatment for HIV-1 largely relies on chemotherapy through the administration of antiretroviral drugs. While the search for anti-HIV-1 vaccine remain elusive, the use of highly active antiretroviral th...

    Authors: Alexander Kwarteng, Samuel Terkper Ahuno and Godwin Kwakye-Nuako

    Citation: AIDS Research and Therapy 2017 14:32

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  6. Content type: Research

    Host immune responses during acute HIV-1 infection can influence the viral setpoint, which is a predictor of disease progression. Interferon (IFN)-lambdas are newly classified type III interferons, which use J...

    Authors: Guoxian Zhao, Lifeng Liu, Bin Su, Tong Zhang, Peng Chen, Wei Li and Hao Wu

    Citation: AIDS Research and Therapy 2017 14:31

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  7. Content type: Research

    To investigate the predictive factors for the development of Kaposi sarcoma-related immune reconstitution inflammatory syndrome (KS-IRIS) and long-term prognosis in patients starting combined antiretroviral th...

    Authors: Patricia Volkow, Gabriela Cesarman-Maus, Pamela Garciadiego-Fossas, Enrique Rojas-Marin and Patricia Cornejo-Juárez

    Citation: AIDS Research and Therapy 2017 14:30

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  8. Content type: Research

    There is growing evidence of the negative impact of alcohol on morbidity and mortality of individuals living with HIV but limited evidence of in utero effects of HIV and alcohol on exposure on infants.

    Authors: Kirsten A. M. Donald, Anne Fernandez, Kasey Claborn, Caroline Kuo, Nastassja Koen, Heather Zar and Dan J. Stein

    Citation: AIDS Research and Therapy 2017 14:28

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  9. Content type: Research

    Abacavir and rilpivirine are alternative antiretroviral drugs for treatment-naïve HIV-infected patients. However, both drugs are only recommended for the patients who have pre-treatment HIV RNA <100,000 copies...

    Authors: Sasisopin Kiertiburanakul, David Boettiger, Oon Tek Ng, Nguyen Van Kinh, Tuti Parwati Merati, Anchalee Avihingsanon, Wing-Wai Wong, Man Po Lee, Romanee Chaiwarith, Adeeba Kamarulzaman, Pacharee Kantipong, Fujie Zhang, Jun Yong Choi, Nagalingeswaran Kumarasamy, Rossana Ditangco, Do Duy Cuong…

    Citation: AIDS Research and Therapy 2017 14:27

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  10. Content type: Research

    Antiretroviral therapy (ART) improves the survival and quality of life of HIV-positive individuals, but the effects of long-term ART use do eventually manifest. The Complications of Long-Term Antiretroviral Th...

    Authors: Billy Nsubuga Mayanja, Ivan Kasamba, Jonathan Levin, Ivan Namakoola, Patrick Kazooba, Jackson Were, Pontiano Kaleebu and Paula Munderi

    Citation: AIDS Research and Therapy 2017 14:26

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  11. Content type: Research

    Immune reconstitution inflammatory syndrome (IRIS) can manifest with initiation or reintroduction of antiretroviral therapy (ART) in persons living with HIV (PLWH). In 2012, updated United States treatment gui...

    Authors: Peter Liu, Rebecca Dillingham and Kathleen A. McManus

    Citation: AIDS Research and Therapy 2017 14:25

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    The Erratum to this article has been published in AIDS Research and Therapy 2017 14:29

  12. Content type: Research

    CSF PCR is the standard diagnostic technique used in resource-rich settings to detect pathogens of the CNS infection. However, it is not currently used for routine CSF testing in China. Knowledge of CNS opport...

    Authors: Rongrong Yang, Hong Zhang, Yong Xiong, Xien Gui, Yongxi Zhang, Liping Deng, Shicheng Gao, Mingqi Luo, Wei Hou and Deyin Guo

    Citation: AIDS Research and Therapy 2017 14:24

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  13. Content type: Research

    There is limited data on factors associated with loss to follow-up (LTFU) of health care workers (HCWs) following occupational exposure to HIV, and most studies were conducted in an era when poorly tolerated a...

    Authors: Nectarios Sophocles Papavarnavas, Kathryn Manning, Fahd Conrad, Milah Govender and Gary Maartens

    Citation: AIDS Research and Therapy 2017 14:23

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  14. Content type: Research

    People with HIV with access to treatment are growing older and living healthier lives than in the past, and while health improvements and increased survival rates are welcome, the psychological and social cons...

    Authors: Jose Catalan, Veronica Tuffrey, Damien Ridge and Dana Rosenfeld

    Citation: AIDS Research and Therapy 2017 14:22

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  15. Content type: Research

    To evaluate psychometric characteristics and cross-sectional and longitudinal validity of the 7-item PROMIS® Fatigue Short Form and additional fatigue items among people living with HIV (PLWH) in a nationally dis...

    Authors: L. E. Gibbons, R. Fredericksen, D. S. Batey, L. Dant, T. C. Edwards, K. H. Mayer, W. C. Mathews, L. S. Morales, M. J. Mugavero, F. M. Yang, E. Paez, M. M. Kitahata, D. L. Patrick, H. M. Crane and P. K. Crane

    Citation: AIDS Research and Therapy 2017 14:21

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  16. Content type: Research

    Incomplete adherence to antiretroviral therapy (ART) results in virologic failure and resistance. It remains unclear which adherence measure best predicts these outcomes. We compared six patient-reported and o...

    Authors: Catherine Orrell, Karen Cohen, Rory Leisegang, David R. Bangsberg, Robin Wood and Gary Maartens

    Citation: AIDS Research and Therapy 2017 14:20

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  17. Content type: Research

    Evaluation of medication efficacy and safety is an essential guarantee to successful therapeutic outcome in public health practices. However, larger distribution chain supply in developing countries such as Ca...

    Authors: M. P. Ngogang Djobet, David Singhe, Julienne Lohoue, Christopher Kuaban, Jeanne Ngogang and Ernest Tambo

    Citation: AIDS Research and Therapy 2017 14:19

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  18. Content type: Research

    Psychosocial factors have been linked with loss to follow-up (LTFU) and clinical outcomes among people living with HIV (PLH), however little is known about the effect of psychosocial support on LTFU among PLH ...

    Authors: Hellen N. Siril, Sylvia F. Kaaya, Mary Kay Smith Fawzi, Expeditho Mtisi, Magreat Somba, Japheth Kilewo, Ferdinand Mugusi, Anna Minja, Anna Kaale and Jim Todd

    Citation: AIDS Research and Therapy 2017 14:18

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  19. Content type: Research

    Early detection of pediatric HIV through uptake of infant HIV testing is critical for access to treatment and child survival. While structural barriers have been well described, a greater understanding of soci...

    Authors: Karen M. Hampanda, Abigail M. Nimz and Lisa L. Abuogi

    Citation: AIDS Research and Therapy 2017 14:17

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  20. Content type: Research

    Adhering 95% and above of antiretroviral therapy reduces the rate of disease progression and death among people’s living human immunodeficiency virus. Though manifold factors have reported as determinant facto...

    Authors: Berhe Beyene Gebrezgabher, Yigzaw Kebede, Melaku Kindie, Desalegn Tetemke, Mebrahtu Abay and Yalemzewod Assefa Gelaw

    Citation: AIDS Research and Therapy 2017 14:16

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  21. Content type: Research

    Progression rates from initial HIV-1 infection to advanced AIDS vary significantly among infected individuals. A distinct subgroup of HIV-1-infected individuals—termed viremic non-progressors (VNP) or controll...

    Authors: Jan Weber, Richard M. Gibson, Lenka Sácká, Dmytro Strunin, Jan Hodek, Jitka Weberová, Marcela Pávová, David J. Alouani, Robert Asaad, Benigno Rodriguez, Michael M. Lederman and Miguel E. Quiñones-Mateu

    Citation: AIDS Research and Therapy 2017 14:15

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  22. Content type: Research

    Adherence and CD4 cell count change measure the progression of the disease in HIV patients after the commencement of HAART. Lack of information about associated factors on adherence to HAART and CD4 cell count...

    Authors: Awoke Seyoum, Principal Ndlovu and Zewotir Temesgen

    Citation: AIDS Research and Therapy 2017 14:14

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  23. Content type: Research

    Moringa oleifera Lam., an herb commonly consumed by HIV-infected people on antiretroviral therapy, inhibits cytochrome P450 3A4, 1A2 and 2D6 activity in vitro; and may alter the pharma...

    Authors: Tsitsi G. Monera-Penduka, Charles C. Maponga, Alan R. Wolfe, Lubbe Wiesner, Gene D. Morse and Charles F. B. Nhachi

    Citation: AIDS Research and Therapy 2017 14:12

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