Skip to content

Advertisement

Articles

Page 2 of 11

  1. Content type: Review

    HIV preferentially infects activated CD4+ T cells and mutates rapidly. The classical vaccine approach aimed to generate broad immune responses to full HIV proteins largely failed to address the potential adver...

    Authors: Hongzhao Li, Robert W. Omange, Francis A. Plummer and Ma Luo

    Citation: AIDS Research and Therapy 2017 14:51

    Published on:

  2. Content type: Review

    Finding new adjuvants is an integrated component of the efforts in developing an effective HIV-1 vaccine. Compared with traditional adjuvants, a modern adjuvant in the context of HIV-1 prevention would elicit ...

    Authors: Jun Liu and Mario Ostrowski

    Citation: AIDS Research and Therapy 2017 14:43

    Published on:

  3. Content type: Review

    Collective evidence supporting a role of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in controlling HIV-1 transmission and disease progression emerged in the last few years. Non-neutralizing antibodie...

    Authors: Jonathan Richard, Shilei Ding and Andrés Finzi

    Citation: AIDS Research and Therapy 2017 14:42

    Published on:

  4. Content type: Review

    Despite the tremendous success of anti-retroviral therapy (ART) no current treatment can eradicate latent HIV reservoirs from HIV-infected individuals or generate, effective HIV-specific immunity. Technologica...

    Authors: Amy E. Baxter, Julia Niessl, Antigoni Morou and Daniel E. Kaufmann

    Citation: AIDS Research and Therapy 2017 14:40

    Published on:

  5. Content type: Review

    The anti-HIV activity of natural killer (NK) cells could be induced fast enough to potentially prevent the establishment of HIV infection. Epidemiological studies identified two genotypes encoding NK receptors...

    Authors: Nicole F. Bernard

    Citation: AIDS Research and Therapy 2017 14:38

    Published on:

  6. Content type: Short Report

    We present a small longitudinal study of how demographic factors and persistent burdens of HIV and cytomegalovirus (CMV) influence cardiovascular health in young adults beginning ART in an inner-city clinic in...

    Authors: Birry Karim, Ika Praseya Wijaya, Rizky Rahmaniyah, Ibnu Ariyanto, Shelley Waters, Riwanti Estiasari and Patricia Price

    Citation: AIDS Research and Therapy 2017 14:52

    Published on:

  7. Content type: Research

    We hypothesized that frailty acts as a measure of health outcomes in the context of LT. The aim of this study was to explore frailty index across LT, as a measure of morbidity and mortality. This was a retrosp...

    Authors: Giovanni Guaraldi, Giovanni Dolci, Stefano Zona, Giuseppe Tarantino, Valentina Serra, Roberto Ballarin, Erica Franceschini, Mauro Codeluppi, Thomas D. Brothers, Cristina Mussini and Fabrizio Di Benedetto

    Citation: AIDS Research and Therapy 2017 14:37

    Published on:

  8. Content type: Research

    Combination antiretroviral therapy (cART) has significantly reduced HIV morbidity and mortality in both developed and developing countries. However, the sustainability of cART may be compromised by the emergen...

    Authors: Elizabeth M. Etta, Lufuno Mavhandu, Cecile Manhaeve, Keanan McGonigle, Patrick Jackson, David Rekosh, Marie-Louise Hammarskjold, Pascal O. Bessong and Denis M. Tebit

    Citation: AIDS Research and Therapy 2017 14:36

    Published on:

  9. Content type: Research

    Safety and immunogenicity of the quadrivalent human papillomavirus (qHPV) vaccine were evaluated in HIV-positive Spanish MSM. The prevalence of High Squamous Intraepithelial Lesions (HSIL) and genotypes of hig...

    Authors: Carmen Hidalgo-Tenorio, Jessica Ramírez-Taboada, Concepción Gil-Anguita, Javier Esquivias, Mohamed Omar-Mohamed-Balgahata, Antonio SamPedro, Miguel Lopez-Ruz and Juan Pasquau

    Citation: AIDS Research and Therapy 2017 14:34

    Published on:

  10. Content type: Research

    Preparing adolescents for transition into adult care and supporting their acquisition of self-health care management skills is a critical determinant of their post-transition HIV care outcomes. However, there ...

    Authors: Siyan Yi, Chanrith Ngin, Khuondyla Pal, Vohith Khol, Sovannary Tuot, Sokunmealiny Sau, Pheak Chhoun, Gitau Mburu, Sok Chamreun Choub, Kolab Chhim and Penhsun Ly

    Citation: AIDS Research and Therapy 2017 14:33

    Published on:

  11. Content type: Review

    Current treatment for HIV-1 largely relies on chemotherapy through the administration of antiretroviral drugs. While the search for anti-HIV-1 vaccine remain elusive, the use of highly active antiretroviral th...

    Authors: Alexander Kwarteng, Samuel Terkper Ahuno and Godwin Kwakye-Nuako

    Citation: AIDS Research and Therapy 2017 14:32

    Published on:

  12. Content type: Research

    Host immune responses during acute HIV-1 infection can influence the viral setpoint, which is a predictor of disease progression. Interferon (IFN)-lambdas are newly classified type III interferons, which use J...

    Authors: Guoxian Zhao, Lifeng Liu, Bin Su, Tong Zhang, Peng Chen, Wei Li and Hao Wu

    Citation: AIDS Research and Therapy 2017 14:31

    Published on:

  13. Content type: Research

    To investigate the predictive factors for the development of Kaposi sarcoma-related immune reconstitution inflammatory syndrome (KS-IRIS) and long-term prognosis in patients starting combined antiretroviral th...

    Authors: Patricia Volkow, Gabriela Cesarman-Maus, Pamela Garciadiego-Fossas, Enrique Rojas-Marin and Patricia Cornejo-Juárez

    Citation: AIDS Research and Therapy 2017 14:30

    Published on:

  14. Content type: Research

    There is growing evidence of the negative impact of alcohol on morbidity and mortality of individuals living with HIV but limited evidence of in utero effects of HIV and alcohol on exposure on infants.

    Authors: Kirsten A. M. Donald, Anne Fernandez, Kasey Claborn, Caroline Kuo, Nastassja Koen, Heather Zar and Dan J. Stein

    Citation: AIDS Research and Therapy 2017 14:28

    Published on:

  15. Content type: Research

    Abacavir and rilpivirine are alternative antiretroviral drugs for treatment-naïve HIV-infected patients. However, both drugs are only recommended for the patients who have pre-treatment HIV RNA <100,000 copies...

    Authors: Sasisopin Kiertiburanakul, David Boettiger, Oon Tek Ng, Nguyen Van Kinh, Tuti Parwati Merati, Anchalee Avihingsanon, Wing-Wai Wong, Man Po Lee, Romanee Chaiwarith, Adeeba Kamarulzaman, Pacharee Kantipong, Fujie Zhang, Jun Yong Choi, Nagalingeswaran Kumarasamy, Rossana Ditangco, Do Duy Cuong…

    Citation: AIDS Research and Therapy 2017 14:27

    Published on:

  16. Content type: Research

    Antiretroviral therapy (ART) improves the survival and quality of life of HIV-positive individuals, but the effects of long-term ART use do eventually manifest. The Complications of Long-Term Antiretroviral Th...

    Authors: Billy Nsubuga Mayanja, Ivan Kasamba, Jonathan Levin, Ivan Namakoola, Patrick Kazooba, Jackson Were, Pontiano Kaleebu and Paula Munderi

    Citation: AIDS Research and Therapy 2017 14:26

    Published on:

  17. Content type: Research

    Immune reconstitution inflammatory syndrome (IRIS) can manifest with initiation or reintroduction of antiretroviral therapy (ART) in persons living with HIV (PLWH). In 2012, updated United States treatment gui...

    Authors: Peter Liu, Rebecca Dillingham and Kathleen A. McManus

    Citation: AIDS Research and Therapy 2017 14:25

    Published on:

    The Erratum to this article has been published in AIDS Research and Therapy 2017 14:29

  18. Content type: Research

    CSF PCR is the standard diagnostic technique used in resource-rich settings to detect pathogens of the CNS infection. However, it is not currently used for routine CSF testing in China. Knowledge of CNS opport...

    Authors: Rongrong Yang, Hong Zhang, Yong Xiong, Xien Gui, Yongxi Zhang, Liping Deng, Shicheng Gao, Mingqi Luo, Wei Hou and Deyin Guo

    Citation: AIDS Research and Therapy 2017 14:24

    Published on:

  19. Content type: Research

    There is limited data on factors associated with loss to follow-up (LTFU) of health care workers (HCWs) following occupational exposure to HIV, and most studies were conducted in an era when poorly tolerated a...

    Authors: Nectarios Sophocles Papavarnavas, Kathryn Manning, Fahd Conrad, Milah Govender and Gary Maartens

    Citation: AIDS Research and Therapy 2017 14:23

    Published on:

  20. Content type: Research

    People with HIV with access to treatment are growing older and living healthier lives than in the past, and while health improvements and increased survival rates are welcome, the psychological and social cons...

    Authors: Jose Catalan, Veronica Tuffrey, Damien Ridge and Dana Rosenfeld

    Citation: AIDS Research and Therapy 2017 14:22

    Published on:

  21. Content type: Research

    To evaluate psychometric characteristics and cross-sectional and longitudinal validity of the 7-item PROMIS® Fatigue Short Form and additional fatigue items among people living with HIV (PLWH) in a nationally dis...

    Authors: L. E. Gibbons, R. Fredericksen, D. S. Batey, L. Dant, T. C. Edwards, K. H. Mayer, W. C. Mathews, L. S. Morales, M. J. Mugavero, F. M. Yang, E. Paez, M. M. Kitahata, D. L. Patrick, H. M. Crane and P. K. Crane

    Citation: AIDS Research and Therapy 2017 14:21

    Published on:

  22. Content type: Research

    Incomplete adherence to antiretroviral therapy (ART) results in virologic failure and resistance. It remains unclear which adherence measure best predicts these outcomes. We compared six patient-reported and o...

    Authors: Catherine Orrell, Karen Cohen, Rory Leisegang, David R. Bangsberg, Robin Wood and Gary Maartens

    Citation: AIDS Research and Therapy 2017 14:20

    Published on:

  23. Content type: Research

    Evaluation of medication efficacy and safety is an essential guarantee to successful therapeutic outcome in public health practices. However, larger distribution chain supply in developing countries such as Ca...

    Authors: M. P. Ngogang Djobet, David Singhe, Julienne Lohoue, Christopher Kuaban, Jeanne Ngogang and Ernest Tambo

    Citation: AIDS Research and Therapy 2017 14:19

    Published on:

  24. Content type: Research

    Psychosocial factors have been linked with loss to follow-up (LTFU) and clinical outcomes among people living with HIV (PLH), however little is known about the effect of psychosocial support on LTFU among PLH ...

    Authors: Hellen N. Siril, Sylvia F. Kaaya, Mary Kay Smith Fawzi, Expeditho Mtisi, Magreat Somba, Japheth Kilewo, Ferdinand Mugusi, Anna Minja, Anna Kaale and Jim Todd

    Citation: AIDS Research and Therapy 2017 14:18

    Published on:

  25. Content type: Research

    Early detection of pediatric HIV through uptake of infant HIV testing is critical for access to treatment and child survival. While structural barriers have been well described, a greater understanding of soci...

    Authors: Karen M. Hampanda, Abigail M. Nimz and Lisa L. Abuogi

    Citation: AIDS Research and Therapy 2017 14:17

    Published on:

  26. Content type: Research

    Adhering 95% and above of antiretroviral therapy reduces the rate of disease progression and death among people’s living human immunodeficiency virus. Though manifold factors have reported as determinant facto...

    Authors: Berhe Beyene Gebrezgabher, Yigzaw Kebede, Melaku Kindie, Desalegn Tetemke, Mebrahtu Abay and Yalemzewod Assefa Gelaw

    Citation: AIDS Research and Therapy 2017 14:16

    Published on:

  27. Content type: Research

    Progression rates from initial HIV-1 infection to advanced AIDS vary significantly among infected individuals. A distinct subgroup of HIV-1-infected individuals—termed viremic non-progressors (VNP) or controll...

    Authors: Jan Weber, Richard M. Gibson, Lenka Sácká, Dmytro Strunin, Jan Hodek, Jitka Weberová, Marcela Pávová, David J. Alouani, Robert Asaad, Benigno Rodriguez, Michael M. Lederman and Miguel E. Quiñones-Mateu

    Citation: AIDS Research and Therapy 2017 14:15

    Published on:

  28. Content type: Research

    Adherence and CD4 cell count change measure the progression of the disease in HIV patients after the commencement of HAART. Lack of information about associated factors on adherence to HAART and CD4 cell count...

    Authors: Awoke Seyoum, Principal Ndlovu and Zewotir Temesgen

    Citation: AIDS Research and Therapy 2017 14:14

    Published on:

  29. Content type: Research

    Early diagnosis of HIV associated lymphoma is challenging because the definitive diagnostic procedure of biopsy, requires skills and equipment that are not readily available. As a consequence, diagnosis may be...

    Authors: Paul Buyego, Lydia Nakiyingi, Henry Ddungu, Stephen Walimbwa, Damalie Nalwanga, Steven J Reynolds and Rosalind Parkes-Ratanshi

    Citation: AIDS Research and Therapy 2017 14:13

    Published on:

  30. Content type: Research

    Moringa oleifera Lam., an herb commonly consumed by HIV-infected people on antiretroviral therapy, inhibits cytochrome P450 3A4, 1A2 and 2D6 activity in vitro; and may alter the pharma...

    Authors: Tsitsi G. Monera-Penduka, Charles C. Maponga, Alan R. Wolfe, Lubbe Wiesner, Gene D. Morse and Charles F. B. Nhachi

    Citation: AIDS Research and Therapy 2017 14:12

    Published on:

  31. Content type: Research

    Occult hepatitis B infection (OBI) among HIV positive patients varies widely in different geographic regions. We undertook a study to determine the prevalence of occult hepatitis B infection among HIV infected...

    Authors: George Gachara, Tshifhiwa Magoro, Lufuno Mavhandu, Emmaculate Lum, Helen K. Kimbi, Roland N. Ndip and Pascal O. Bessong

    Citation: AIDS Research and Therapy 2017 14:11

    Published on:

  32. Content type: Research

    Approximately 0.8% of adults aged 18–49 in Myanmar are seropositive for Human Immunodeficiency Virus (HIV). Identifying the demographic, epidemiological and clinical characteristics of people living with HIV (...

    Authors: Ne Myo Aung, Josh Hanson, Tint Tint Kyi, Zaw Win Htet, David A. Cooper, Mark A. Boyd, Mar Mar Kyi and Htin Aung Saw

    Citation: AIDS Research and Therapy 2017 14:10

    Published on:

  33. Content type: Research

    Late presentation (LP) at the time of HIV diagnosis is defined as presentation with AIDS whatever the CD4 cell count or with CD4 <350 cells/mm. The objective of our study was to assess the prevalence of non-in...

    Authors: Giovanni Guaraldi, Stefano Zona, Marianna Menozzi, Thomas D. Brothers, Federica Carli, Chiara Stentarelli, Giovanni Dolci, Antonella Santoro, Ana Rita Domingues Da Silva, Elisa Rossi, Julian Falutz and Cristina Mussini

    Citation: AIDS Research and Therapy 2017 14:8

    Published on:

  34. Content type: Short report

    Antigen-induced activation and proliferation of HIV-1-infected cells is hypothesized to be a mechanism of HIV persistence during antiretroviral therapy. The objective of this study was to determine if prolifer...

    Authors: Thor A. Wagner, Hannah C. Huang, Christen E. Salyer, Kelly M. Richardson, Adriana Weinberg, Sharon Nachman and Lisa M. Frenkel

    Citation: AIDS Research and Therapy 2017 14:7

    Published on:

  35. Content type: Research

    The prevalence of bipolar disorder in HIV-infected patients is higher than the general population. Lithium is the most effective mood stabiliser, while tenofovir disoproxil fumarate (TDF) is frequently used as...

    Authors: Eric H. Decloedt, Maia Lesosky, Gary Maartens and John A. Joska

    Citation: AIDS Research and Therapy 2017 14:6

    Published on:

  36. Content type: Research

    Tenofovir (TDF) based regimen was reported to have better immunological outcomes. Unfortunately, there is limited information regarding the immunologic outcome associated with this regimen in Ethiopia, as its ...

    Authors: Teshale Ayele, Habtemu Jarso and Girma Mamo

    Citation: AIDS Research and Therapy 2017 14:5

    Published on:

  37. Content type: Research

    To understand HIV-1 drug resistance in 11 prefectures of Hebei Province, China, we implemented a cross-sectional HIV-1 molecular epidemiological survey.

    Authors: Xinli Lu, Hongru Zhao, Yuqi Zhang, Wei Wang, Cuiying Zhao, Yan Li, Lin Ma, Ze Cui and Suliang Chen

    Citation: AIDS Research and Therapy 2017 14:4

    Published on:

  38. Content type: Review

    Regular monitoring of HIV patients who are receiving antiretroviral therapy (ART) is required to ensure patient benefits and the long-term effectiveness and sustainability of ART programs. Prompted by WHO reco...

    Authors: Minh D. Pham, Lorena Romero, Bruce Parnell, David A. Anderson, Suzanne M. Crowe and Stanley Luchters

    Citation: AIDS Research and Therapy 2017 14:3

    Published on:

  39. Content type: Research

    Codon usage bias has been described for various organisms and is thought to contribute to the regulation of numerous biological processes including viral infections. HIV-1 codon usage has been previously shown...

    Authors: Navaneethan Palanisamy, Nathan Osman, Frédéric Ohnona, Hong-Tao Xu, Bluma Brenner, Thibault Mesplède and Mark A. Wainberg

    Citation: AIDS Research and Therapy 2017 14:2

    Published on:

  40. Content type: Research

    This cross-sectional study took place in the integrated tuberculosis (TB) clinic of a large outpatient clinic for HIV-infected patients in Kampala, Uganda. The purpose of this study was to describe the proport...

    Authors: Amrei von Braun, Christine Sekaggya-Wiltshire, Alexandra U. Scherrer, Brian Magambo, Andrew Kambugu, Jan Fehr and Barbara Castelnuovo

    Citation: AIDS Research and Therapy 2017 14:1

    Published on:

  41. Content type: Review

    Cryptococcosis has been one of the most common opportunistic infections and causes of mortality among HIV-infected patients, especially in resource-limited countries. Cryptococcal meningitis is the most common...

    Authors: Sirawat Srichatrapimuk and Somnuek Sungkanuparph

    Citation: AIDS Research and Therapy 2016 13:42

    Published on:

  42. Content type: Research

    New simian–human immunodeficiency chimeric viruses with an HIV-1 env (SHIVenv) are critical for studies on HIV pathogenesis, vaccine development, and microbicide testing. Macaques are typically exposed to sing...

    Authors: Kendall C. Krebs, Meijuan Tian, Mohammed Asmal, Binhua Ling, Kenneth Nelson, Kenneth Henry, Richard Gibson, Yuejin Li, Weining Han, Robin J. Shattock, Ronald S. Veazey, Norman Letvin, Eric J. Arts and Yong Gao

    Citation: AIDS Research and Therapy 2016 13:41

    Published on: