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  1. Raltegravir (RAL) has favorable tolerability and safety profile, with few and manageable drug interactions. The use of RAL 1200 mg once daily (qd) for first-line therapy is well established. We assessed effica...

    Authors: Nolwenn Hall, Clotilde Allavena, Christine Katlama, Alexandra Jobert, Jean-Michel Molina, Eric Cua, Firouzé Bani-Sadr, Laurent Hocqueloux, Claudine Duvivier, Dominique Merrien, Hitoto Hikombo, Elisabeth André-Garnier, Aurélie Gaultier and François Raffi
    Citation: AIDS Research and Therapy 2022 19:4
  2. Data on the association of human immunodeficiency virus (HIV) infection with adverse outcomes in patients with COVID-19 are conflicting. This systematic review and meta-analysis aimed to summarize the availabl...

    Authors: Celestin Danwang, Jean Jacques Noubiap, Annie Robert and Jean Cyr Yombi
    Citation: AIDS Research and Therapy 2022 19:3
  3. We developed a personalized Monocyte-Derived Dendritic-cell Therapy (MDDCT) for HIV-infected individuals on suppressive antiretroviral treatment and evaluated HIV-specific T-cell responses.

    Authors: Marcella Vassão de Almeida Baptista, Laís Teodoro da Silva, Sadia Samer, Telma Miyuki Oshiro, Iart Luca Shytaj, Leila B. Giron, Nathalia Mantovani Pena, Nicolly Cruz, Gisele Cristina Gosuen, Paulo Roberto Abrão Ferreira, Edécio Cunha-Neto, Juliana Galinskas, Danilo Dias, Maria Cecilia Araripe Sucupira, Cesar de Almeida-Neto, Reinaldo Salomão…
    Citation: AIDS Research and Therapy 2022 19:2
  4. Retention in clinical care is important for people living with HIV (PLWH). Evidence suggests that missed clinic visits are associated with interruptions in antiretroviral therapy (ART), lower CD4 counts, virol...

    Authors: Nicole Dear, Allahna Esber, Michael Iroezindu, Emmanuel Bahemana, Hannah Kibuuka, Jonah Maswai, John Owuoth, Christina S. Polyak, Julie A. Ake and Trevor A. Crowell
    Citation: AIDS Research and Therapy 2022 19:1
  5. In 2018, approximately 1.6 million adolescents (aged 10–19) were living with HIV worldwide, with the highest HIV prevalence found in Eswatini. Adolescents and young adults living with HIV are a vulnerable popu...

    Authors: Tara E. Ness, Vedika Agrawal, Danielle Guffey, Amanda Small, Tandzile Simelane, Sandile Dlamini, Jaime Petrus and Bhekumusa Lukhele
    Citation: AIDS Research and Therapy 2021 18:100
  6. Ethiopia, being in the Sub Saharan region of Africa, is one of the countries with a substantial burden of HIV infection. Because of the high burden of HIV and poor health care settings, HAND is prevalent as de...

    Authors: Yosef Zenebe, Baye Akele, Mulugeta W/Selassie and Mogesie Necho
    Citation: AIDS Research and Therapy 2021 18:99
  7. Adolescents are at increased risk of HIV infection compared to other age groups. There is an urgent need for strategic information that will inform programmes to reduce risk and vulnerability to HIV and revers...

    Authors: Musawenkosi Mabaso, Goitseone Maseko, Ronel Sewpaul, Inbarani Naidoo, Sean Jooste, Sinovuyo Takatshana, Tarylee Reddy, Khangelani Zuma and Nompumelelo Zungu
    Citation: AIDS Research and Therapy 2021 18:97
  8. Late presentation to HIV/AIDS care presents serious health concerns, like increased transmission and high healthcare costs, increased mortality, early development of opportunistic infection, increased risk of ...

    Authors: Chengqing Sun, Jianjun Li, Xiaoyan Liu, Zhi Zhang, Tao Qiu, Haiyang Hu, You Wang and Gengfeng Fu
    Citation: AIDS Research and Therapy 2021 18:96
  9. AIDS as a human crisis may lead to devastating psychological trauma and stress for patients. Therefore, it is necessary to study different aspects of their lives for better support and care. Accordingly, this ...

    Authors: Behzad Imani, Shirdel Zandi, Salman khazaei and Mohamad Mirzaei
    Citation: AIDS Research and Therapy 2021 18:95
  10. Tenofovir disoproxil fumarate (TDF) has a strong antiviral effect, but TDF is known to cause renal dysfunction. Therefore, we are investigating preventing renal dysfunction by replacing TDF with tenofovir alaf...

    Authors: Kensuke Abe, Taku Obara, Satomi Kamio, Asahi Kondo, Junji Imamura, Tatsuya Goto, Toshihiro Ito, Hiroshi Sato and Nobuyuki Takahashi
    Citation: AIDS Research and Therapy 2021 18:94
  11. Anti-retroviral therapy regimen discontinuations become a big challenge and cause diminishing the clinical and immunological benefit of treatment in Ethiopia. It reduces both the duration and the chance of vir...

    Authors: Tewodros Getnet Amera, Kassawmar Angaw Bogale and Yibekal Manaye Tefera
    Citation: AIDS Research and Therapy 2021 18:93
  12. This study aims to evaluate the safety of inactivated COVID-19 vaccine among adult people living with HIV (PLWH). In total, 259 PLWH who received at least one dose of inactivated COVID-19 vaccine were enrolled...

    Authors: Songjie Wu, Yubin Zhang, Fangzhao Ming, Shi Zou, Mengmeng Wu, Wei Guo, Weiming Tang and Ke Liang
    Citation: AIDS Research and Therapy 2021 18:92
  13. Adolescents are lagging behind in the “third 95” objective of the Joint United Nations Program on HIV/AIDS requiring 95% of individuals on antiretroviral therapy (ART) to have viral load (VL) suppression. This...

    Authors: Joel Maena, Aduragbemi Banke-Thomas, Nelson Mukiza, Cynthia Ndikuno Kuteesa, Ronald Makanga Kakumba, Hajira Kataike, Samuel Kizito, Juliet Allen Babirye and Rita Nakalega
    Citation: AIDS Research and Therapy 2021 18:91
  14. Disseminated Mycobacterium avium complex infection is an important indicator of acquired immunodeficiency syndrome (AIDS) in patients with advanced human immunodeficiency virus (HIV) infection. Effective antiretr...

    Authors: Keiji Konishi, Hidenori Nakagawa, Akio Nakahira, Takahiro Okuno, Takeshi Inoue and Michinori Shirano
    Citation: AIDS Research and Therapy 2021 18:90
  15. Increased availability of HIV care over the past decade has dramatically reduced morbidity and mortality among people living with HIV (PLWH) in sub-Saharan Africa. However, perceived and experienced barriers t...

    Authors: Nancy Somi, Nicole Dear, Domonique Reed, Ajay Parikh, Anange Lwilla, Emmanuel Bahemana, Samoel Khamadi, Michael Iroezindu, Hannah Kibuuka, Jonah Maswai, Trevor A. Crowell, John Owuoth, Lucas Maganga, Christina Polyak, Julie Ake and Allahna Esber
    Citation: AIDS Research and Therapy 2021 18:89
  16. World Health Organization (WHO) reports that people who indulge in risky behaviours such as penile-anal sex, unprotected intercourse, multiple sex partners, and alcohol and illicit drugs are at risk of HIV/AID...

    Authors: Olawale Durosinmi-Etti, Emmanuel Kelechi Nwala, Funke Oki, Akudo Ikpeazu, Emmanuel Godwin, Paul Umoh, Arome Shaibu, Alex Ogundipe and Abiye Kalaiwo
    Citation: AIDS Research and Therapy 2021 18:88
  17. Events associated with the COVID-19 pandemic, such as physical distancing, closure of community services, postponement of health appointments, and loss of employment can lead to social isolation, financial unc...

    Authors: Kelly K. O’Brien, Ahmed M. Bayoumi, Soo Chan Carusone, Aileen M. Davis, Rachel Aubry, Lisa Avery, Patricia Solomon, Kristine M. Erlandson, Colm Bergin, Richard Harding, Darren A. Brown, Jaime H. Vera and Steven E. Hanna
    Citation: AIDS Research and Therapy 2021 18:87
  18. Thoracic actinomycosis is an uncommon, chronic, and progressive infection, especially in patients with HIV. We report a case of thoracic actinomycosis presenting as an isolated pleural effusion in a patient wi...

    Authors: Jung Wan Park, Yon Hee Kim, Eunjung Lee, Se Yoon Park and Tae Hyong Kim
    Citation: AIDS Research and Therapy 2021 18:86
  19. Programmes that merge management of Human Immunodeficiency Virus (HIV) and tuberculosis (TB) aim to improve HIV/TB co-infected patients’ access to comprehensive treatment. However, several reports from sub-Sah...

    Authors: Benjamin Momo Kadia, Christian Akem Dimala, Noah T. Fongwen and Adrian D. Smith
    Citation: AIDS Research and Therapy 2021 18:85
  20. In 2007–2012 the Mexican government launched the National HIV program and there was a major change in HIV policies implemented in 2013–2018, when efforts focused on prevention, increase in early diagnosis and ...

    Authors: Amilcar Azamar-Alonso, Sergio A. Bautista-Arredondo, Fiona Smaill, Lawrence Mbuagbaw, Andrew P. Costa and Jean-Eric Tarride
    Citation: AIDS Research and Therapy 2021 18:84
  21. Accelerated atherosclerosis in older HIV-infected patients has been attributed to persistent immune activation and high burden cytomegalovirus (CMV), as demonstrated in transplant recipients and the general po...

    Authors: Ika Prasetya Wijaya, Birry Karim, Mohamad Syahrir Azizi, Ibnu Ariyanto, Arif Mansjoer, Evy Yunihastuti, Kuntjoro Harimurti, Idrus Alwi, Silvia Lee and Patricia Price
    Citation: AIDS Research and Therapy 2021 18:83
  22. To evaluate the effect of reconstruction and repair, using a mini-plate and bone graft for HIV -positive patients with giant cell tumor of long bone.

    Authors: Biao Xu, Rui Ma, Wen-sheng Zhang, Qiang Zhang, Chang-song Zhao and Jie Wang
    Citation: AIDS Research and Therapy 2021 18:82
  23. Socioeconomic, demographic and clinical factors can affect adherence to treatment among people living with HIV (PLH) and potentially have an impact on their prognosis and survival. The main objective of this s...

    Authors: Ludentz Dorcélus, Joseph Bernard Jr., Constant Georgery and Clerveau Vanessa
    Citation: AIDS Research and Therapy 2021 18:81
  24. The efficacy and tolerability of an antiretroviral regimen are important considerations for selection of HIV-1 infection maintenance therapy. Abacavir/lamivudine plus rilpivirine (ABC/3TC + RPV) has been shown...

    Authors: Z. C. Lim, G. S. Hoo, J. H. Ang, C. B. Teng, L. W. Ang, C. C. Lee, Y. S. Leo, H. L. Law, O. T. Ng and C. S. Wong
    Citation: AIDS Research and Therapy 2021 18:80
  25. Viral suppression prevents HIV transmission and disease progression, but socio-economic and clinical factors can hinder the goal of suppression. We evaluated factors associated with viral non suppression (VNS)...

    Authors: Dean W. Ortíz, Olivia Roberts-Sano, Hugo E. Marroquin, Lindsey Larson, Katherine B. Franco, Andrej Spec, Johanna R. Melendez, Rodolfo Pinzón, Ana J. Samayoa, Carlos Mejia-Chew and Jane A. O´Halloran
    Citation: AIDS Research and Therapy 2021 18:79
  26. Symptoms of primary HIV infection, including fever, rash, and headache, are nonspecific and are often described as flu-like. COVID-19 vaccination side effects, such as fever, which occur in up to 10% of people...

    Authors: Julian Triebelhorn, Stefanie Haschka, Felix Hesse, Johanna Erber, Simon Weidlich, Marcel Lee, Dieter Hoffmann, Josef Eberle and Christoph D. Spinner
    Citation: AIDS Research and Therapy 2021 18:78
  27. Targeting RNA is a promising yet underdeveloped modality for the selective killing of cells infected with HIV-1. The secretory ribonucleases (RNases) found in vertebrates have cytotoxic ribonucleolytic activit...

    Authors: Ian W. Windsor, Dawn M. Dudley, David H. O’Connor and Ronald T. Raines
    Citation: AIDS Research and Therapy 2021 18:77
  28. AIDS-related primary central nervous system lymphoma (AR-PCNSL) is an AIDS-defining disease that usually occurs when the CD4 count is less than 50 cells/μl. The frequency of the disease has substantially decre...

    Authors: Pieter-Jan Gijs and Olivier Clerc
    Citation: AIDS Research and Therapy 2021 18:76
  29. An increasing number of HIV cure trials involve combining multiple potentially curative interventions. Until now, considerations for designing and implementing complex combination HIV cure trials have not been...

    Authors: Karine Dubé, John Kanazawa, Lynda Dee, Jeff Taylor, John A. Sauceda, Sara Gianella, Davey Smith, Steven G. Deeks and Michael J. Peluso
    Citation: AIDS Research and Therapy 2021 18:75
  30. Introduction of tenofovir (TDF) plus lamivudine (3TC) and dolutegravir (DTG) in first- and second-line HIV treatment regimens in South Africa warrants characterization of acquired HIV-1 drug resistance (ADR) m...

    Authors: Benjamin Chimukangara, Richard J. Lessells, Lavanya Singh, Indra Grigalionyte, Nonhlanhla Yende-Zuma, Rochelle Adams, Halima Dawood, Linda Dlamini, Sibonisile Buthelezi, Sheldon Chetty, Karidia Diallo, Wayne A. Duffus, Mary Mogashoa, Melissa B. Hagen, Jennifer Giandhari, Tulio de Oliveira…
    Citation: AIDS Research and Therapy 2021 18:74
  31. A 73-year-old male patient who had a history of Human Immunodeficiency Virus (HIV) infection for over 20 years was diagnosed with SARS-CoV-2 infection.

    Authors: Pedro Vieira Bertozzi, Amanda de Oliveira Vicente, Amanda Siqueira Pereira, Joao Pedro Espinha de Sant’Ana, Rafaela Braga Cabrera Mano, Luciana Souza Jorge and Rodrigo Afonso da Silva Sardenberg
    Citation: AIDS Research and Therapy 2021 18:73
  32. The growing burden of the HIV and non-communicable disease (NCD) syndemic in Sub- Saharan Africa has necessitated introduction of integrated models of care in order to leverage existing HIV care infrastructure...

    Authors: Blessings Gausi, Natacha Berkowitz, Nisha Jacob and Tolu Oni
    Citation: AIDS Research and Therapy 2021 18:72
  33. The availability and accessibility of effective antiretroviral therapy (ART) for people living with HIV (PLWH) has substantially improved in the past two decades in resource-limited settings. Therefore, evalua...

    Authors: Weerawat Manosuthi, Lantharita Charoenpong and Chalor Santiwarangkana
    Citation: AIDS Research and Therapy 2021 18:71
  34. Medical care re-engagement is critical to suppressing viral load and preventing HIV transmission, morbidity and mortality, yet few rigorous intervention studies address this outcome. We assessed the effectiven...

    Authors: Mary K. Irvine, McKaylee M. Robertson, Denis Nash, Sarah G. Kulkarni, Sarah L. Braunstein and Bruce Levin
    Citation: AIDS Research and Therapy 2021 18:70
  35. The current standard of care is to start antiretroviral therapy in all patients diagnosed with HIV-1, as for HIV-2 current DHHS guideline suggests ART for HIV-2 as soon as diagnosis is established, although th...

    Authors: Margarida Cardoso, Joana Vasconcelos, Teresa Baptista, Isabel Diogo, Fátima Gonçalves, Kamal Mansinho and Perpétua Gomes
    Citation: AIDS Research and Therapy 2021 18:69
  36. Men who have sex with men (MSM) are potentially at high risk for HIV infection, their HIV prevalence far exceeds the national prevalence rate. There are also a number of MSM who have sex with women, mostly unp...

    Authors: Huan Zhao, Xi Li, Junhua Wang, Wen Wang, Chunyan Yang, Jingjuan Li, Xiuling Li, Rui Pu, Lulu Chen, Xiao Zhang, Jun Zhang, Peng Luo and Jiangping Zhang
    Citation: AIDS Research and Therapy 2021 18:68
  37. Men who have Sex with Men (MSM) represent the risk group that are disproportionately most affected by the human immunodeficiency virus (HIV) and continue to drop-off from the steps of the continuum of HIV serv...

    Authors: Willy Dunbar, Marie Colette Alcide Jean-Pierre, Jacky S. Pétion, Aline Labat, Nathalie Maulet and Yves Coppieters
    Citation: AIDS Research and Therapy 2021 18:67
  38. Achieving undetectable viral load is crucial for the reduction of HIV transmissions, AIDS-related illnesses and death. Adolescents (10 to19 years) living with HIV (ALHIV) on antiretroviral treatment (ART) have...

    Authors: Emeka F. Okonji, Brian van Wyk, Ferdinand C. Mukumbang and Gail D. Hughes
    Citation: AIDS Research and Therapy 2021 18:66
  39. Reduction of the reservoir of latent HIV-infected cells might increase the possibility of long-term remission in individuals living with HIV. We investigated factors associated with HIV-1 proviral DNA levels i...

    Authors: Helen Payne, Man K. Chan, Sarah A. Watters, Kennedy Otwombe, Nei-Yuan Hsiao, Abdel Babiker, Avy Violari, Mark F. Cotton, Diana M. Gibb and Nigel J. Klein
    Citation: AIDS Research and Therapy 2021 18:63
  40. To accelerate progress toward the UNAIDS 90-90-90 targets, US Centers for Disease Control and Prevention Nigeria country office (CDC Nigeria) initiated an Antiretroviral Treatment (ART) Surge in 2019 to identi...

    Authors: Andrew T. Boyd, Ibrahim Jahun, Emilio Dirlikov, Stacie Greby, Solomon Odafe, Alhassan Abdulkadir, Olugbenga Odeyemi, Ibrahim Dalhatu, Obinna Ogbanufe, Andrew Abutu, Olugbenga Asaolu, Moyosola Bamidele, Chibuzor Onyenuobi, Timothy Efuntoye, Johnson O. Fagbamigbe, Uzoma Ene…
    Citation: AIDS Research and Therapy 2021 18:62
  41. This study investigates the willingness of men-who-have-sex-with-men (MSM) to use HIV pre-exposure prophylaxis (PrEP). Research in the HIV/AIDS field typically relies on clinical and epidemiological studies, t...

    Authors: Michele Pazzini, Zsófia S. Ignácz and Julia Tuppat
    Citation: AIDS Research and Therapy 2021 18:61
  42. Mental health problems (e.g., depression and anxiety) are among the most commonly reported comorbidities of HIV. Antiretroviral therapy (ART) coverage has increased sharply. The purposes of this prospective co...

    Authors: Jinzhao Xie, Zixin Wang, Quanmin Li, Qiangsheng He, Guohong Xu, Yonghong Li, Kai Zhou, Linghua Li and Jing Gu
    Citation: AIDS Research and Therapy 2021 18:60
  43. We estimated the predictive effects of ART-related perceptions on the actual ART uptake behavior among ART naïve PLWH stratified by different time of HIV diagnosis under the new strategy.

    Authors: Tinglong Yang, Xueying Yang, Linghua Li, Huifang Xu, Lirui Fan, Quanmin Li, Xiaoyan Fan, Weiyi Chen, Xuan Du, Chun Hao, Jinghua Li, Yuantao Hao and Jing Gu
    Citation: AIDS Research and Therapy 2021 18:59
  44. The DUALIS study showed that switching to boosted darunavir (bDRV) plus dolutegravir (DTG; 2DR) was non-inferior to continuous bDRV plus 2 nucleoside/nucleotide reverse-transcriptase inhibitors (NRTIs; 3DR) in...

    Authors: Eva Wolf, Christoph Boesecke, Annamaria Balogh, Helen Bidner, Christiane Cordes, Hans Heiken, Ivanka Krznaric, Tim Kümmerle, Hans-Jürgen Stellbrink, Jochen Schneider and Christoph D. Spinner
    Citation: AIDS Research and Therapy 2021 18:58
  45. Although individual antiretroviral drugs have been shown to be associated with elevated cardiovascular disease (CVD) risk, data are limited on the role of antiretroviral drug combinations. Therefore, we sought...

    Authors: Kunchok Dorjee, Manisha Desai, Tsering Choden, Sanjiv M. Baxi, Alan E. Hubbard and Arthur L. Reingold
    Citation: AIDS Research and Therapy 2021 18:57
  46. We report a case of sudden, lethal metabolic acidosis in a 70-year-old man on long-term nucleoside reverse transcriptase inhibitor (NRTI) -based antiretroviral therapy (ART) who had developed atypical necrotiz...

    Authors: Alexa Hollinger, Nadine Cueni, Catia Marzolini, Michael Dickenmann, Emmanuelle Landmann, Manuel Battegay, Aurélien Emmanuel Martinez, Martin Siegemund and Anne Leuppi-Taegtmeyer
    Citation: AIDS Research and Therapy 2021 18:56
  47. For over a decade, antiretroviral therapy (ART) in resource-limited countries was only recommended for patients with advanced HIV disease. We investigated this group of patients in order to determine any relat...

    Authors: Godfrey Barabona, Macdonald Mahiti, Mako Toyoda, Doreen Kamori, Salim Masoud, George P. Judicate, Bruno Sunguya, Eligius Lyamuya and Takamasa Ueno
    Citation: AIDS Research and Therapy 2021 18:55