UNAIDS: UNAIDS annual report 2009.
Google Scholar
Haase AT: Perils at mucosal front lines for HIV and SIV and their hosts. Nat Rev Immunol. 2005, 5: 783-792. 10.1038/nri1706
Article
CAS
PubMed
Google Scholar
Gupta K, Klasse PJ: How do viral and host factors modulate the sexual transmission of HIV? Can transmission be blocked?. PLoS Med. 2006, 3: e79- 10.1371/journal.pmed.0030079
Article
PubMed Central
PubMed
Google Scholar
Sabatte J, Lenicov FR, Cabrini M, Rodriguez CR, Ostrowski M, Ceballos A, Amigorena S, Geffner J: The role of semen in sexual transmission of HIV: beyond a carrier for virus particles. Microbes Infect. 2011, 13: 977-982. 10.1016/j.micinf.2011.06.005
Article
PubMed
Google Scholar
Münch J, Rücker E, Ständker L, Adermann K, Goffinet C, Schindler M, Wildum S, Chinnadurai R, Rajan D, Specht A: Semen-derived amyloid fibrils drastically enhance HIV infection. Cell. 2007, 131: 1059-1071. 10.1016/j.cell.2007.10.014
Article
PubMed
Google Scholar
Roan NR, Greene WC: A seminal finding for understanding HIV transmission. Cell. 2007, 131: 1044-1046. 10.1016/j.cell.2007.11.030
Article
CAS
PubMed
Google Scholar
Hauber I, Hohenberg H, Holstermann B, Hunstein W, Hauber J: The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection. Proc Natl Acad Sci USA. 2009, 106: 9033-9038. 10.1073/pnas.0811827106
Article
PubMed Central
CAS
PubMed
Google Scholar
Abdool Karim Q, Abdool Karim SS, Frohlich JA, Grobler AC, Baxter C, Mansoor LE, Kharsany ABM, Sibeko S, Mlisana KP, Omar Z: Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science. 2010, 329: 1168-1174. 10.1126/science.1193748
Article
PubMed Central
CAS
PubMed
Google Scholar
Wang L, Schnaare RL, Dezzutti C, Anton PA, Rohan LC: Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. AIDS Res Ther. 2011, 8: 12- 10.1186/1742-6405-8-12
Article
PubMed Central
PubMed
Google Scholar
World Health Organization: WHO Laboratory Manual for the examination of human semen and sperm-cervical mucus interaction.1999, Cambridge University Press, 4,
Google Scholar
Ehrnhoefer DE, Bieschke J, Boeddrich A, Herbst M, Masino L, Lurz R, Engemann S, Pastore A, Wanker EE: EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nat Struct Mol Biol. 2008, 15: 558-566. 10.1038/nsmb.1437
Article
CAS
PubMed
Google Scholar
Kim K-A, Yolamanova M, Zirafi O, Roan NR, Staendker L, Forssmann W-G, Burgener A, Dejucq-Rainsford N, Hahn BH, Shaw GM: Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Retrovirology. 2010, 7: 55- 10.1186/1742-4690-7-55
Article
PubMed Central
PubMed
Google Scholar
Wurm M, Schambach A, Lindemann D, Hanenberg H, Standker L, Forssmann WG, Blasczyk R, Horn PA: The influence of semen-derived enhancer of virus infection on the efficiency of retroviral gene transfer. J Gene Med. 2010, 12: 137-146.
CAS
PubMed
Google Scholar
Martellini JA, Cole AL, Venkataraman N, Quinn GA, Svoboda P, Gangrade BK, Pohl J, Sorensen OE, Cole AM: Cationic polypeptides contribute to the anti-HIV-1 activity of human seminal plasma. FASEB J. 2009, 23: 3609-3618. 10.1096/fj.09-131961
Article
PubMed Central
CAS
PubMed
Google Scholar
Martellini JA, Cole AL, Svoboda P, Stuchlik O, Chen LM, Chai KX, Gangrade BK, Sorensen OE, Pohl J, Cole AM: HIV-1 enhancing effect of prostatic acid phosphatase peptides is reduced in human seminal plasma. PLoS One. 2011, 6: e16285- 10.1371/journal.pone.0016285
Article
PubMed Central
CAS
PubMed
Google Scholar
Malm J, Hellman J, Hogg P, Lilja H: Enzymatic action of prostate-specific antigen (PSA or hK3): substrate specificity and regulation by Zn(2+), a tight-binding inhibitor. Prostate. 2000, 45: 132-139. 10.1002/1097-0045(20001001)45:2<132::AID-PROS7>3.0.CO;2-3
Article
CAS
PubMed
Google Scholar
Kawai K, Tsuno NH, Kitayama J, Okaji Y, Yazawa K, Asakage M, Hori N, Watanabe T, Takahashi K, Nagawa H: Epigallocatechin gallate, the main component of tea polyphenol, binds to CD4 and interferes with gp120 binding. J Allergy Clin Immunol. 2003, 112: 951-957. 10.1016/S0091-6749(03)02007-4
Article
CAS
PubMed
Google Scholar
Liu S, Lu H, Zhao Q, He Y, Niu J, Debnath AK, Wu S, Jiang S: Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41. Biochim Biophys Acta. 2005, 1723: 270-281. 10.1016/j.bbagen.2005.02.012
Article
CAS
PubMed
Google Scholar
Nance CL, Siwak EB, Shearer WT: Preclinical development of the green tea catechin, epigallocatechin gallate, as an HIV-1 therapy. J Allergy Clin Immunol. 2009, 123: 459-465. 10.1016/j.jaci.2008.12.024
Article
PubMed Central
CAS
PubMed
Google Scholar
Williamson MP, McCormick TG, Nance CL, Shearer WT: Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. J Allergy Clin Immunol. 2006, 118: 1369-1374. 10.1016/j.jaci.2006.08.016
Article
CAS
PubMed
Google Scholar
Isaacs CE, Wen GY, Xu W, Jia JH, Rohan L, Corbo C, Di Maggio V, Jenkins EC, Hillier S: Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus. Antimicrob Agents Chemother. 2008, 52: 962-970. 10.1128/AAC.00825-07
Article
PubMed Central
CAS
PubMed
Google Scholar
Ciesek S, von Hahn T, Colpitts CC, Schang LM, Friesland M, Steinmann J, Manns MP, Ott M, Wedemeyer H, Meuleman P: The green tea polyphenol epigallocatechin-3-gallate (EGCG) inhibits hepatitis C virus (HCV) entry. Hepatology. 2011,
Google Scholar
Bettuzzi S, Brausi M, Rizzi F, Castagnetti G, Peracchia G, Corti A: Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer Res. 2006, 66: 1234-1240. 10.1158/0008-5472.CAN-05-1145
Article
CAS
PubMed
Google Scholar
Chow H-HS, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA, Dorr RT, Hara Y, Alberts DS: Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res. 2003, 9: 3312-3319.
CAS
PubMed
Google Scholar
Chow HH, Cai Y, Alberts DS, Hakim I, Dorr R, Shahi F, Crowell JA, Yang CS, Hara Y: Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. Cancer Epidemiol Biomarkers Prev. 2001, 10: 53-58.
CAS
PubMed
Google Scholar
Ullmann U, Haller J, Decourt JP, Girault N, Girault J, Richard-Caudron AS, Pineau B, Weber P: A single ascending dose study of epigallocatechin gallate in healthy volunteers. J Int Med Res. 2003, 31: 88-101.
Article
CAS
PubMed
Google Scholar
Stratton SP, Bangert JL, Alberts DS, Dorr RT: Dermal toxicity of topical (-)epigallocatechin-3-gallate in BALB/c and SKH1 mice. Cancer Lett. 2000, 158: 47-52. 10.1016/S0304-3835(00)00498-5
Article
CAS
PubMed
Google Scholar
Wei X, Decker JM, Liu H, Zhang Z, Arani RB, Kilby JM, Saag MS, Wu X, Shaw GM, Kappes JC: Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob Agents Chemother. 2002, 46: 1896-1905. 10.1128/AAC.46.6.1896-1905.2002
Article
PubMed Central
CAS
PubMed
Google Scholar
Platt EJ, Wehrly K, Kuhmann SE, Chesebro B, Kabat D: Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J Virol. 1998, 72: 2855-2864.
PubMed Central
CAS
PubMed
Google Scholar
Gartner S, Markovits P, Markovitz DM, Kaplan MH, Gallo RC, Popovic M: The role of mononuclear phagocytes in HTLV-III/LAV infection. Science. 1986, 233: 215-219. 10.1126/science.3014648
Article
CAS
PubMed
Google Scholar
Adachi A, Gendelman HE, Koenig S, Folks T, Willey R, Rabson A, Martin MA: Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol. 1986, 59: 284-291.
PubMed Central
CAS
PubMed
Google Scholar
Hohenberg H, Mannweiler K, Muller M: High-pressure freezing of cell suspensions in cellulose capillary tubes. J Microsc. 1994, 175: 34-43. 10.1111/j.1365-2818.1994.tb04785.x
Article
CAS
PubMed
Google Scholar