Table 1 Participant Characteristics, Unadjusted Lipoprotein Levels, by HIV Serostatus and CD4 Count
From: Lipoprotein levels and cardiovascular risk in HIV-infected and uninfected Rwandan women
HIV negative N = 218 | HIV+ women (all) N = 606 | P-value | HIV+ CD4 > 350 n = 158 | HIV+ CD4 200-350 n = 224 | HIV+ CD4 < 200 n = 222 | P-value | |
|---|---|---|---|---|---|---|---|
Age (years) Mean (SD) | 42.4 (10.5) | 34.7 (6.8) | < 0.0001 | 34.0 (6.8) | 34.9 (6.5) | 34.9 (7.2) | 0.35 |
Body Mass Index (Kg/m 2 ) | |||||||
Median (IQR) | 20.6 (18.6,23.5) | 21.1 (19.1, 23.4) | 0.40 | 21.7 (19.0,23.8) | 21.3 (19.2,24.0) | 20.9 (19.0,23.1) | 0.068 |
Total Body Fat (Kg) | |||||||
Median (IQR) | 11.4 (6.6, 19.0) | 12.0 (7.9, 17.0) | 0.95 | 11.4 (7.9, 16.5) | 12.1 (7.75, 17.5) | 12.1 (7.9, 16.4) | 0.43 |
Lean Body Mass (Kg) | |||||||
Median (IQR) | 41.8 (38.7, 44.9) | 40.0 (37.2, 43.0) | 0.0006 | 40.5 (38.4, 43.5) | 40.4 (37.5, 44.2) | 39.3 (35.9, 42.0) | 0.013 |
Post-menopausal (%) | 22.2 | 5.7 | < 0.0001 | 6.6 | 4.9 | 5.9 | 0.79 |
# Sexual partners 1 | |||||||
Mean (SD) | 3.6 (5.4) | 7.5 (22.7) | 0.015 | 6.3 (15.0) | 7.5 (23.9) | 8.5(26.0) | 0.66 |
Median (IQR) | 2 (1, 4) | 3 (2, 6) | 3 (2, 5) | 3 (2, 5) | 3 (2, 6) | ||
Smoking (%) | 3.4 | 2.5 | 0.50 | 2.6 | 2.7 | 2.3 | 0.96 |
Alcohol | 0.40 | 0.73 | |||||
None | 77.1 | 81.0 | 83.5 | 80.4 | 79.3 | ||
1-3 drinks/day | 22.5 | 18.3 | 16.5 | 18.8 | 19.4 | ||
> 3 drinks/day | 0.5 | 0.7 | 0.0 | 0.9 | 0.9 | ||
Illicit drug use (%) | 3.5 | 2.7 | 0.57 | 1.9 | 2.7 | 3.2 | 0.74 |
Food adequacy (%) | 0.41 | 0.67 | |||||
Always | 0.5 | 1.6 | 2.0 | 0.9 | 2.1 | ||
Most of the time | 6.7 | 5.4 | 6.8 | 4.2 | 5.6 | ||
Some of the time | 48.3 | 43.2 | 41.9 | 48.1 | 39.2 | ||
Usually not | 32.3 | 37.5 | 35.1 | 36.1 | 40.2 | ||
Never | 12.1 | 12.3 | 14.2 | 10.7 | 12.9 | ||
Running water in home (%) | 4.1 | 4.8 | 0.70 | 5.9 | 4.5 | 4.3 | 0.76 |
Education (%) | 0.0002 | ||||||
No schooling | 36.2 | 23.3 | 24.7 | 21.0 | 24.8 | 0.32 | |
Grade 1-6 | 52.8 | 67.0 | 68.4 | 70.1 | 62.6 | ||
Grade 7-11 | 7.8 | 8.4 | 7.0 | 7.1 | 10.8 | ||
Completed high school | 2.3 | 1.3 | 0.0 | 1.8 | 1.8 | ||
Some college | 0.9 | 0.0 | 0.0 | 0.0 | 0.0 | ||
Monthly Income $US Mean (SD) | 38 (37.0) | 38 (30.3) | 0.98 | 38 (30.2) | 37 (30.3) | 39 (30.4) | 0.89 |
Diabetes Mellitus (%) | 0.5 | 0.5 | 0.98 | 0.7 | 0.5 | 0.5 | 0.96 |
CD4 cell count (cells/mm 3 ) | |||||||
Mean (SD) | 878 (299) | 275 (163) | < 0.0001 | 487 (137) | 274 (43) | 124 (51) | < 0.0001 |
HIV-1 RNA* (log 10 ) | n = 271 | n = 34 | n = 93 | n = 143 | |||
Mean (SD) | --- | 4.06 (1.37) | --- | 3.73 (1.40) | 3.94 (1.39) | 4.22 (1.35) | 0.100 |
Lipoprotein Levels, mg/dl | |||||||
Mean (SD) | |||||||
LDL | 71 (29.7) | 68 (28.9) | 0.20 | 67 (25.3) | 68 (26.) | 67 (33.3) | 0.98 |
HDL | 54 (16.9) | 44 (17.3) | < 0.0001 | 46 (14.5) | 45 (19.5) | 43 (16.7) | 0.13 |
Non-HDL | 89 (33.6) | 86 (31.2) | 0.21 | 84 (27.6) | 86 (30.7) | 87 (34.3) | 0.59 |
Triglycerides | 87 (42.0) | 94 (47,9) | 0.11 | 82 (32.6) | 93(51.6) | 102 (50.9) | 0.003 |
Total Cholesterol | 143 (36.4) | 129 (33.9) | < 0.0001 | 129 (31.5) | 130 (32.4) | 130 (37.1) | 0.92 |