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Table 1 Participant Characteristics, Unadjusted Lipoprotein Levels, by HIV Serostatus and CD4 Count

From: Lipoprotein levels and cardiovascular risk in HIV-infected and uninfected Rwandan women

  HIV negative
N = 218
HIV+ women (all)
N = 606
P-value HIV+ CD4 > 350
n = 158
HIV+ CD4 200-350
n = 224
HIV+ CD4
< 200
n = 222
P-value
Age (years) Mean (SD) 42.4 (10.5) 34.7 (6.8) < 0.0001 34.0 (6.8) 34.9 (6.5) 34.9 (7.2) 0.35
Body Mass Index (Kg/m 2 )        
Median (IQR) 20.6 (18.6,23.5) 21.1
(19.1, 23.4)
0.40 21.7 (19.0,23.8) 21.3 (19.2,24.0) 20.9 (19.0,23.1) 0.068
Total Body Fat (Kg)        
Median (IQR) 11.4
(6.6, 19.0)
12.0
(7.9, 17.0)
0.95 11.4
(7.9, 16.5)
12.1
(7.75, 17.5)
12.1
(7.9, 16.4)
0.43
Lean Body Mass (Kg)        
Median (IQR) 41.8
(38.7, 44.9)
40.0
(37.2, 43.0)
0.0006 40.5
(38.4, 43.5)
40.4
(37.5, 44.2)
39.3
(35.9, 42.0)
0.013
Post-menopausal (%) 22.2 5.7 < 0.0001 6.6 4.9 5.9 0.79
# Sexual partners 1        
Mean (SD) 3.6 (5.4) 7.5 (22.7) 0.015 6.3 (15.0) 7.5 (23.9) 8.5(26.0) 0.66
Median (IQR) 2 (1, 4) 3 (2, 6)   3 (2, 5) 3 (2, 5) 3 (2, 6)  
Smoking (%) 3.4 2.5 0.50 2.6 2.7 2.3 0.96
Alcohol    0.40     0.73
None 77.1 81.0   83.5 80.4 79.3  
1-3 drinks/day 22.5 18.3   16.5 18.8 19.4  
> 3 drinks/day 0.5 0.7   0.0 0.9 0.9  
Illicit drug use (%) 3.5 2.7 0.57 1.9 2.7 3.2 0.74
Food adequacy (%)    0.41     0.67
Always 0.5 1.6   2.0 0.9 2.1  
Most of the time 6.7 5.4   6.8 4.2 5.6  
Some of the time 48.3 43.2   41.9 48.1 39.2  
Usually not 32.3 37.5   35.1 36.1 40.2  
Never 12.1 12.3   14.2 10.7 12.9  
Running water in home (%) 4.1 4.8 0.70 5.9 4.5 4.3 0.76
Education (%)    0.0002     
No schooling 36.2 23.3   24.7 21.0 24.8 0.32
Grade 1-6 52.8 67.0   68.4 70.1 62.6  
Grade 7-11 7.8 8.4   7.0 7.1 10.8  
Completed high school 2.3 1.3   0.0 1.8 1.8  
Some college 0.9 0.0   0.0 0.0 0.0  
Monthly Income $US
Mean (SD)
38 (37.0) 38 (30.3) 0.98 38 (30.2) 37 (30.3) 39 (30.4) 0.89
Diabetes Mellitus (%) 0.5 0.5 0.98 0.7 0.5 0.5 0.96
CD4 cell count (cells/mm 3 )        
Mean (SD) 878 (299) 275 (163) < 0.0001 487 (137) 274 (43) 124 (51) < 0.0001
HIV-1 RNA* (log 10 )   n = 271   n = 34 n = 93 n = 143  
Mean (SD) --- 4.06 (1.37) --- 3.73 (1.40) 3.94 (1.39) 4.22 (1.35) 0.100
Lipoprotein Levels, mg/dl        
Mean (SD)        
LDL 71 (29.7) 68 (28.9) 0.20 67 (25.3) 68 (26.) 67 (33.3) 0.98
HDL 54 (16.9) 44 (17.3) < 0.0001 46 (14.5) 45 (19.5) 43 (16.7) 0.13
Non-HDL 89 (33.6) 86 (31.2) 0.21 84 (27.6) 86 (30.7) 87 (34.3) 0.59
Triglycerides 87 (42.0) 94 (47,9) 0.11 82 (32.6) 93(51.6) 102 (50.9) 0.003
Total Cholesterol 143 (36.4) 129 (33.9) < 0.0001 129 (31.5) 130 (32.4) 130 (37.1) 0.92
  1. 1 includes rape; *HIV-1 RNA levels available for 271 women; LDL = low density lipoprotein cholesterol; HDL = high density lipoprotein cholesterol, Non-HDL = Total Cholesterol - HDL.