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  1. In resource poor countries like Ethiopia, little is known about the survival of patients treated with antiretroviral therapy which depends on different factors. Evidence shows that mortality has been high part...

    Authors: Abewa Kebede, Fasil Tessema, Gadisa Bekele, Zerihun Kura and Hailu Merga
    Citation: AIDS Research and Therapy 2020 17:49
    Content type: Research Published on:

  2. In Sub-Saharan Africa where HIV disproportionately affects women, heterosexual male sex workers (HMSW) and their female clients are at risk of acquiring or transmitting HIV and other STIs. However, few studies...

    Authors: Richard Muhindo, Andrew Mujugira, Barbara Castelnuovo, Nelson K. Sewankambo, Rosalind Parkes-Ratanshi, Juliet Kiguli, Nazarius Mbona Tumwesigye and Edith Nakku-Joloba
    Citation: AIDS Research and Therapy 2020 17:48
    Content type: Research Published on:

  3. It is well known that people living with HIV (PLWH) is in higher risk for the development of depression and it has also been suggested that the use of efavirenz into the antiretroviral regimens increases even ...

    Authors: Alejandro Checa, Alberto Castillo, Malena Camacho, William Tapia, Isabel Hernandez and Enrique Teran
    Citation: AIDS Research and Therapy 2020 17:47
    Content type: Short Report Published on:

  4. The COVID-19 has been a severe pandemic all around the world. Nowadays the patient with co-infection of HIV and SARS-CoV-2 was rarely reported. Here we reported a special case with HIV and SARS-CoV-2 co-infect...

    Authors: Wu Menghua, Zheng Xin, Liu Jianwei, Zhang Yu and Yao Qinwei
    Citation: AIDS Research and Therapy 2020 17:46
    Content type: Case Report Published on:

  5. The aim of this study was to investigate the effectiveness and tolerability of the combination elvitegravir/cobicistat/tenofovir/emtricitabine plus darunavir (EVG/COB/TFV/FTC + DRV) in treatment-experienced pa...

    Authors: Inés Suárez-García, Cristina Moreno, Marta Ruiz-Algueró, María Jesús Pérez-Elías, Marta Navarro, Marcos Díez Martínez, Pompeyo Viciana, Laura Pérez-Martínez, Miguel Górgolas, Concha Amador, Miguel Alberto de Zárraga and Inma Jarrín
    Citation: AIDS Research and Therapy 2020 17:45
    Content type: Research Published on:

  6. To evaluate the impact of AIDS-defining events (ADE) on long-term mortality of HIV positive individuals on antiretroviral therapy (ART), a retrospective HIV/AIDS treatment cohort study performed in Southwester...

    Authors: Yunxuan Huang, Oulu Zhou, Zhigang Zheng, Yuexiang Xu, Yi Shao, Chunwei Qin, Fengxiang Qin, Jingzhen Lai, Huifang Liu, Rongfeng Chen, Li Ye, Hao Liang, Xionglin Qin and Junjun Jiang
    Citation: AIDS Research and Therapy 2020 17:44
    Content type: Research Published on:

  7. Early detection of viremia in HIV infected patients on anti-retroviral therapy (ART) is important to prevent disease progression as well as accumulation of drug resistance mutations. This makes HIV viral load ...

    Authors: Ashwini Shete, Sampada Dhayarkar, Ashwini Dhamanage, Smita Kulkarni, Manisha Ghate, Shashikala Sangle, Uttam Medhe, Vinita Verma, Shobini Rajan, Toshio Hattori and Raman Gangakhedkar
    Citation: AIDS Research and Therapy 2020 17:43
    Content type: Research Published on:

  8. HIV status disclosure facilitates receipt of HIV prevention and treatment services. Although disclosure to sexual partners, family members or friends has been extensively studied, disclosure to community-based...

    Authors: John Charles, Amon Exavery, Asheri Barankena, Erica Kuhlik, Godfrey M. Mubyazi, Ramadhani Abdul, Alison Koler, Levina Kikoyo and Elizabeth Jere
    Citation: AIDS Research and Therapy 2020 17:42
    Content type: Research Published on:

  9. In pregnancy, reduction of HIV plasma viral load (pVL) for the prevention of vertical transmission is time-constrained. The study primary objective is to investigate factors associated with faster initial HIV ...

    Authors: Jasmini Alagaratnam, Helen Peters, Kate Francis, Natasha Kay, Yvonne Gilleece, Fionnuala P. Finnerty, Rosanna E. Grimes, Sarah Parry, Mags Portman, Brenton C. Wait, Rimi Shah, Sherie Roedling, David A. Hawkins, Sarah Chitty, Liat Sarner, Rebecca Marcus…
    Citation: AIDS Research and Therapy 2020 17:41
    Content type: Research Published on:

  10. The US President’s Emergency Plan for AIDS Relief (PEPFAR) was launched to increase access to antiretroviral treatment (ART) among people living with HIV (PLHIV) and to prevent new HIV infections globally. As ...

    Authors: Andrew T. Boyd, Ikwo Oboho, Heather Paulin, Hammad Ali, Catherine Godfrey, Anand Date and J. Sean Cavanaugh
    Citation: AIDS Research and Therapy 2020 17:40
    Content type: Review Published on:

  11. Antiretroviral treatment has played a pivotal role in the reduction of HIV/AIDS-related morbidity and mortality. However, treatment options can be impaired by the development of antiretroviral treatment failur...

    Authors: Jemberu Nega, Solomon Taye, Yihenew Million, Chaturaka Rodrigo and Setegn Eshetie
    Citation: AIDS Research and Therapy 2020 17:39
    Content type: Research Published on:

  12. Vacuolar encephalomyelopathy, a disregarded diagnosis lately, was a major neurological disease in the terminal stages of human immunodeficiency virus (HIV)-1 infection in the pre-antiretroviral therapy (ART) e...

    Authors: Kazumasa Akagi, Kazuko Yamamoto, Asuka Umemura, Shotaro Ide, Tatsuro Hirayama, Takahiro Takazono, Yoshifumi Imamura, Taiga Miyazaki, Noriho Sakamoto, Hirokazu Shiraishi, Hideaki Takahata, Yoshiaki Zaizen, Junya Fukuoka, Minoru Morikawa, Kazuto Ashizawa, Katsuji Teruya…
    Citation: AIDS Research and Therapy 2020 17:38
    Content type: Case Report Published on:

  13. The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individ...

    Authors: Vijay Harypursat, Yihong Zhou, Shengquan Tang and Yaokai Chen
    Citation: AIDS Research and Therapy 2020 17:37
    Content type: Review Published on:

  14. The link between food insecurity and depression in people living with HIV/AIDS (PLWHA) has been explored in numerous studies; however, the existing evidence is inconclusive due to inconsistent results. Therefo...

    Authors: Getinet Ayano, Light Tsegay and Melat Solomon
    Citation: AIDS Research and Therapy 2020 17:36
    Content type: Review Published on:

  15. Adolescents living with HIV (ALHIV) in Malawi experience multiple challenges associated with their illness and various social, environmental, economic and cultural factors. In exploring their various medical c...

    Authors: Blessings N. Kaunda-Khangamwa, Prosperina Kapwata, Kennedy Malisita, Alister Munthali, Effie Chipeta, Sam Phiri and Lenore Manderson
    Citation: AIDS Research and Therapy 2020 17:35
    Content type: Research Published on:

  16. Long acting and permanent contraceptive methods by far are the most effective, very safe and convenient methods than short acting contraceptive methods. But in less developed countries, use of long acting reve...

    Authors: Betselot Yirsaw, Feleke Gebremeskel, Gebrekiros Gebremichael and Tewoderos Shitemaw
    Citation: AIDS Research and Therapy 2020 17:34
    Content type: Research Published on:

  17. Female sex workers (FSW) are considered a key group for HIV transmissions in sub-Saharan Africa. The HIV Care Continuum and HIV drug resistance (HIVDR) among FSW has not been well studied in most countries in ...

    Authors: Jacob Lindman, Mamadu Aliu Djalo, Ansu Biai, Fredrik Månsson, Joakim Esbjörnsson, Marianne Jansson, Patrik Medstrand and Hans Norrgren
    Citation: AIDS Research and Therapy 2020 17:33
    Content type: Research Published on:

  18. Door-to-door distribution of HIV self-testing kits (HIVST) has the potential to increase uptake of HIV testing services (HTS). However, very few studies have explored the social response to and implications of...

    Authors: Chiti Bwalya, Musonda Simwinga, Bernadette Hensen, Lwiindi Gwanu, Able Hang’andu, Chama Mulubwa, Mwelwa Phiri, Richard Hayes, Sarah Fidler, Alwyn Mwinga, Helen Ayles and Virginia Bond
    Citation: AIDS Research and Therapy 2020 17:32
    Content type: Research Published on:

  19. In the era of “test and treat strategy”, CD4 testing remains an important tool for monitoring HIV-infected individuals. Since conventional methods of CD4 count measurement are costly and cumbersome, POC CD4 co...

    Authors: Elmir Elharti, Halima Abbadi, Rajae Bensghir, Kamal Marhoum El Filali, Hajar Elmrabet and Hicham Oumzil
    Citation: AIDS Research and Therapy 2020 17:31
    Content type: Research Published on:

  20. Despite initial high motivation, individuals receiving antiretroviral therapy (ART) for several years may experience incomplete adherence over time, increasing their risk of HIV-related morbidity and mortality...

    Authors: Larissa Jennings Mayo-Wilson, Bianca Devoto, Jessica Coleman, Barbara Mukasa, Angela Shelton, Sarah MacCarthy, Uzaib Saya, Harriet Chemusto and Sebastian Linnemayr
    Citation: AIDS Research and Therapy 2020 17:30
    Content type: Research Published on:

  21. This study aimed to investigate the measures of retention in care (RIC) in persons living with HIV (PLWH) and type 2 diabetes mellitus (T2DM) by age group (younger vs. older adults).

    Authors: Julie Ann Zuniga, Alexandra A. García, Junse Lee and Jungmin Park
    Citation: AIDS Research and Therapy 2020 17:29
    Content type: Research Published on:

  22. Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection constitute a deadly infectious disease synergy disease and major public health problem throughout the world. The risk of developing active ...

    Authors: Simon Sensalire, Esther Karungi Karamagi Nkolo, Juliana Nabwire, Anna Lawino, Dithan Kiragga, Martin Muhire, Herbert Kadama, Cordelia Katureebe, Proscovia Namuwenge, Joshua Musinguzi, Jacqueline Calnan and Dejene Seyoum
    Citation: AIDS Research and Therapy 2020 17:28
    Content type: Research Published on:

  23. The pressing need to expand the biomedical HIV prevention evidence base during pregnancy is now increasingly recognized. Women’s views regarding participation in such trials and initiating PrEP while pregnant ...

    Authors: Kristen Sullivan, Tiwonge Mtande, Elana Jaffe, Nora Rosenberg, Chifundo Zimba, Irving Hoffman, Maggie Little, Ruth Faden and Anne Drapkin Lyerly
    Citation: AIDS Research and Therapy 2020 17:27
    Content type: Research Published on:

  24. The clinical and laboratory characteristics of AIDS-associated Talaromyces marneffei infection, a rare but a fatal mycosis disease of the central nervous system, remain unclear.

    Authors: Yu-Ye Li, Rong-Jing Dong, Samip Shrestha, Pratishtha Upadhyay, Hui-Qin Li, Yi-Qun Kuang, Xin-Ping Yang and Yun-Gui Zhang
    Citation: AIDS Research and Therapy 2020 17:26
    Content type: Case Report Published on:

  25. Metabolic complications in human immunodeficiency virus (HIV)-infected individuals are common. Prediabetes represents a high risk for future diabetes development. This study aimed to determine the prevalence, ...

    Authors: Angsana Phuphuakrat, Hataikarn Nimitphong, Sirimon Reutrakul and Somnuek Sungkanuparph
    Citation: AIDS Research and Therapy 2020 17:25
    Content type: Research Published on:

  26. To explore the use of illicit drugs by people living with HIV (PLHIV) taking antiretroviral therapy (ART) and their relationship with variables relevant to the management of HIV infection, such as knowledge an...

    Authors: María José Fuster-RuizdeApodaca, Vanessa Castro-Granell, Ana Laguía, Ángeles Jaén, Santiago Cenoz and María José Galindo
    Citation: AIDS Research and Therapy 2020 17:24
    Content type: Research Published on:

  27. The anti-retroviral combination of abacavir/lamivudine plus rilpivirine (ABC/3TC/RPV) is not recommended by international guidelines as the first-line regimen. However, it is potent, well-tolerated, and afford...

    Authors: Sharlene Ho, Joshua Guoxian Wong, Oon Tek Ng, Cheng Chuan Lee, Yee Sin Leo, David Chien Boon Lye and Chen Seong Wong
    Citation: AIDS Research and Therapy 2020 17:23
    Content type: Research Published on:

  28. Pre-treatment drug resistance (PDR) among antiretroviral drug-naïve people living with HIV (PLHIV) represents an important indicator for the risk of treatment failure and the spread of drug resistant HIV varia...

    Authors: F. Neuhann, A. de Forest, E. Heger, A. Nhlema, C. Scheller, R. Kaiser, H. M. Steffen, H. Tweya, G. Fätkenheuer and S. Phiri
    Citation: AIDS Research and Therapy 2020 17:22
    Content type: Research Published on:

  29. People living with HIV are living longer, and can experience physical, mental and social health challenges associated with aging and multimorbidity. Rehabilitation is well positioned to address disability and ...

    Authors: Kelly K. O’Brien, Francisco Ibáñez-Carrasco, Patricia Solomon, Richard Harding, Darren Brown, Puja Ahluwalia, Soo Chan Carusone, Larry Baxter, Charles Emlet, Gayle Restall, Alan Casey, Amrita Ahluwalia, Adria Quigley, Alex R. Terpstra and Nkem Ononiwu
    Citation: AIDS Research and Therapy 2020 17:21
    Content type: Research Published on:

  30. Perinatal HIV infection negatively impacts cognitive functioning of children, main domains affected are working memory, processing speed and executive function. Early ART, even when interrupted, improves neuro...

    Authors: Christelle Ackermann, Savvas Andronikou, Muhammad G. Saleh, Martin Kidd, Mark F. Cotton, Ernesta M. Meintjes and Barbara Laughton
    Citation: AIDS Research and Therapy 2020 17:20
    Content type: Research Published on:

  31. Through universal “test and treat approach” (UTT) it is believed that HIV new infection and AIDS related death will be reduced at community level and through time HIV can be eliminated. With this assumption th...

    Authors: Tadele Girum, Fedila Yasin, Abebaw Wasie, Teha Shumbej, Fitsum Bekele and Bereket Zeleke
    Citation: AIDS Research and Therapy 2020 17:19
    Content type: Research Published on:

  32. About 13 years since the introduction of antiretroviral therapy (ART) for children living with HIV (CLHIV) in Zambia, HIV/AIDS testing and treatment guidelines for children have evolved over the years with lim...

    Authors: Tendai Munthali, Charles Michelo, Paul Mee, Crispin Moyo, Andrew Kashoka, Liswaniso Liswaniso, Innocent Chiboma and Jim Todd
    Citation: AIDS Research and Therapy 2020 17:18
    Content type: Research Published on:

  33. Data on the survival status of older adults on antiretroviral treatment (ART) are scarce in sub-Saharan Africa. The objective of this study was to determine the survival status of people aged 50 years and olde...

    Authors: Joseph Mugisha Okello, Stephen Nash, Paul Kowal, Nirmala Naidoo, Somnath Chatterji, Ties Boerma and Janet Seeley
    Citation: AIDS Research and Therapy 2020 17:17
    Content type: Research Published on:

  34. People with HIV (PHIV) with limited access to health services often experience suboptimal antiretroviral therapy (ART) adherence. We investigated whether a daily text messaging intervention improves ART adhere...

    Authors: Elizabeth M. Sherman, Jianli Niu, Shara Elrod, Kevin A. Clauson, Fadi Alkhateeb and Paula Eckardt
    Citation: AIDS Research and Therapy 2020 17:16
    Content type: Research Published on:

  35. Increased intestinal barrier permeability and subsequent gut microbial translocation are significant contributors to inflammatory non-AIDS comorbidities in people living with HIV (PLWH). Evidence in animal mod...

    Authors: Jing Ouyang, Stéphane Isnard, John Lin, Brandon Fombuena, Debashree Chatterjee, Tomas Raul Wiche Salinas, Delphine Planas, Amélie Cattin, Augustine Fert, Etiene Moreira Gabriel, Laurence Raymond Marchand, Yonglong Zhang, Malcolm Finkelman, Yaokai Chen, Daniel E. Kaufmann, Nicolas Cermakian…
    Citation: AIDS Research and Therapy 2020 17:15
    Content type: Short Report Published on:

  36. The high rate of mortality among HIV-vertically infected adolescents might be favoured by HIV drug resistance (HIVDR) emergence, which calls for timeous actions in this underserved population. We thus sought t...

    Authors: Joseph Fokam, Armanda Nangmo, Carlson Wandum, Desire Takou, Maria Mercedes Santoro, Anne-Esther Njom Nlend, Francis Ndongo Ateba, Paul Koki Ndombo, Nelly Kamgaing, Cedric Kamta, Andre Essiane, Virginie Lambo, Charles Fokunang, Dora Mbanya, Vittorio Colizzi, Carlo-Federico Perno…
    Citation: AIDS Research and Therapy 2020 17:14
    Content type: Research Published on:

  37. The objectives of this study were to investigate the relationships between polymorphisms at the interferon lambda (IFNL) locus and CD4+:CD8+ ratio normalisation in people living with HIV (PLWH) on effective antir...

    Authors: Inês T. Freitas, Willard Tinago, Hirofumi Sawa, Julie McAndrews, Brenda Doak, Charlotte Prior-Fuller, Gerard Sheehan, John S. Lambert, Eavan Muldoon, Aoife G. Cotter, William W. Hall, Patrick W. G. Mallon and Michael J. Carr
    Citation: AIDS Research and Therapy 2020 17:13
    Content type: Research Published on:

  38. Once-daily, single-tablet regimens (STRs) have been associated with improved patient outcomes compared to multi-tablet regimens (MTRs). This study evaluated real world adherence and persistence of HIV antiretr...

    Authors: Joshua Cohen, Anne Beaubrun, Richa Bashyal, Ahong Huang, Jieni Li and Onur Baser
    Citation: AIDS Research and Therapy 2020 17:12
    Content type: Research Published on:

  40. The gut microbiota is emerging as a prominent player in maintaining health through several metabolic and immune pathways. Dysregulation of gut microbiota composition, also known as dysbiosis, is involved in th...

    Authors: Jing Ouyang, Stéphane Isnard, John Lin, Brandon Fombuena, André Marette, Bertrand Routy, Yaokai Chen and Jean-Pierre Routy
    Citation: AIDS Research and Therapy 2020 17:10
    Content type: Review Published on:

  41. The aim of this study was to assess trends in drug resistance and associated clinical and programmatic factors at a national level during the rapid scale up of ART.

    Authors: Pengtao Liu, Hui Xing, Lingjie Liao, Yi Feng, Xuebing Leng, Jing Wang, Wei Kan, Jing Yan, Yang Li, Zhongbao Zuo, Yinghui You, Yuhua Ruan and Yiming Shao
    Citation: AIDS Research and Therapy 2020 17:9
    Content type: Research Published on:

  42. Antiretroviral adherence is essential to HIV treatment efficacy. Various self-reported measures are commonly used for assessing antiretroviral adherence. Limited data are available regarding the validity of th...

    Authors: Quan Zhang, Xiaoming Li, Shan Qiao, Zhiyong Shen and Yuejiao Zhou
    Citation: AIDS Research and Therapy 2020 17:8
    Content type: Research Published on:

  43. Expanded access to combination antiretroviral therapy (cART) throughout sub-Saharan Africa over the last decade has remarkably improved the prognosis of persons living with HIV (PLWH). However, some PLWH exper...

    Authors: Ernest Ekong, Nicaise Ndembi, Prosper Okonkwo, Patrick Dakum, John Idoko, Bolanle Banigbe, James Okuma, Patricia Agaba, William Blattner, Clement Adebamowo and Manhattan Charurat
    Citation: AIDS Research and Therapy 2020 17:7
    Content type: Research Published on:

  44. In resource-limited settings, multi-experienced HIV infected patients are often prescribed raltegravir for salvage therapy. Patients failing raltegravir-containing regimens require other drugs including other ...

    Authors: Aurelio Orta-Resendiz, Roberto A. Rodriguez-Diaz, Luis A. Angulo-Medina, Mario Hernandez-Flores and Luis E. Soto-Ramirez
    Citation: AIDS Research and Therapy 2020 17:6
    Content type: Research Published on:

  45. Entry inhibitors, such as Maraviroc, hold promise as components of HIV treatment and/or pre-exposure prophylaxis in Africa. Maraviroc inhibits the interaction between HIV Envelope gp120 V3-loop and CCR5 corece...

    Authors: Nontokozo D. Matume, Denis M. Tebit and Pascal O. Bessong
    Citation: AIDS Research and Therapy 2020 17:5
    Content type: Review Published on:

  46. For migrant female sex workers (FSWs) at the Sino-Vietnamese border, the impact of work time in their current location on the spread of HIV/AIDS is not clear.

    Authors: Yu Zhang, Bingyu Liang, Deping Liu, Guangwu Wei, Shide Mo, Aidan Nong, Chuanyi Ning, Yanyan Liao, Junjun Jiang, PeiJiang Pan, Yuan Yang, Ning Zang, Dinh Vanphu, Nguyen Van, Li Ye, Hao Liang…
    Citation: AIDS Research and Therapy 2020 17:4
    Content type: Research Published on:

  47. Despite advances in the treatment quality of HIV throughout the world, several countries are still facing numerous obstacles in delivering HIV treatment at a sufficiently high quality, putting patients’ lives ...

    Authors: S. Jespersen, F. Månsson, J. Lindman, C. Wejse, C. Medina, Z. J. da Silva, DdS Te, P. Medstrand, J. Esbjörnsson and B. L. Hønge
    Citation: AIDS Research and Therapy 2020 17:3
    Content type: Review Published on:

  48. Resistance to antiretroviral drugs is a major challenge among Human Immunodeficiency Virus (HIV) positive patients receiving antiretroviral therapy (ART). Mutations that arise as a result of this are diverse a...

    Authors: Alisen Ayitewala, Fred Kyeyune, Pamela Ainembabazi, Eva Nabulime, Charles Drago Kato and Immaculate Nankya
    Citation: AIDS Research and Therapy 2020 17:2
    Content type: Research Published on:

  49. Dolutegravir (DTG)-based antiretroviral therapy (ART) is currently the first-line treatment for people living with HIV. Neuropsychiatric adverse events (NP-AEs) have been reported with DTG but neuropsychiatric...

    Authors: Phillip Chan, Orlanda Goh, Eugène Kroon, Donn Colby, Carlo Sacdalan, Suteeraporn Pinyakorn, Peeriya Prueksakaew, Peter Reiss, Jintanat Ananworanich, Victor Valcour, Serena Spudich and Robert Paul
    Citation: AIDS Research and Therapy 2020 17:1
    Content type: Research Published on:

  50. Tenofovir disoproxil fumarate (TDF) is widely used in the management of HIV-infection, but has been associated with renal impairment in a small proportion of patients. Tenofovir alafenamide (TAF), a novel prod...

    Authors: Dane Turner, Douglas Drak, Catherine C. O’Connor, David J. Templeton and David M. Gracey
    Citation: AIDS Research and Therapy 2019 16:40
    Content type: Research Published on:

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AIDS Research and Therapy

ISSN: 1742-6405

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