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  1. Women in sub-Saharan Africa continue to be at greater risk for HIV acquisition than men. Concurrency, viz. multiple sexual partnerships that overlap over time, has been studied as a possible risk factor for HI...

    Authors: Zakir Gaffoor, Handan Wand, Renée A. Street, Nathlee Abbai and Gita Ramjee

    Citation: AIDS Research and Therapy 2016 13:14

    Content type: Research

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  2. HIV is usually associated with weight loss. World health Organization (WHO) recommends early antiretroviral (ART) initiation, but data on the progression of body mass index (BMI) in participants initiating ear...

    Authors: Calixte Guehi, Anani Badjé, Delphine Gabillard, Eric Ouattara, Serge Olivier Koulé, Raoul Moh, Didier Ekouevi, Hugues Ahibo, Jean Baptiste N’Takpé, Gérard Kouamé Menan, Nina Deschamps, Jerôme Lecarrou, Serge Eholié, Xavier Anglaret and Christine Danel

    Citation: AIDS Research and Therapy 2016 13:12

    Content type: Research

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  3. Ready-to-use supplementary food (RUSF) is increasingly used as a component of food rations for adults with HIV.

    Authors: Anne G. Beckett, Debbie Humphries, J. Gregory Jerome, Jessica E. Teng, Patrick Ulysse and Louise C. Ivers

    Citation: AIDS Research and Therapy 2016 13:11

    Content type: Research

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  4. Regimen change is a major challenge for the sustainability of human immunodeficiency virus (HIV) treatment program. In a resource limited setting where treatment options are limited, designing strategies to in...

    Authors: Degefaye Zelalem Anlay, Zinahbizu Abay Alemayehu and Berihun Assefa Dachew

    Citation: AIDS Research and Therapy 2016 13:10

    Content type: Research

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  5. Human immunodeficiency virus (HIV) Rapid diagnostic Test (RDT) kits are the preferred assays for HIV testing in many countries. Prevention of Mother-to-Child Transmission, Know Your Status Campaigns, Blood-Saf...

    Authors: Raymond Boadu, George Darko, Priscilla Nortey, Patricia Akweongo and Bismark Sarfo

    Citation: AIDS Research and Therapy 2016 13:9

    Content type: Research

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  6. Long acting antiretroviral drugs represent a promising approach for chronic treatment of HIV infection. Here, we study the efficacy and safety of albuvirtide (ABT), an HIV-1 fusion inhibitor with a half life ...

    Authors: Hongwei Zhang, Ronghua Jin, Cheng Yao, Tong Zhang, Meixia Wang, Wei Xia, Haiyan Peng, Xiaojuan Wang, Rongjian Lu, Changjin Wang, Dong Xie and Hao Wu

    Citation: AIDS Research and Therapy 2016 13:8

    Content type: Research

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  7. Previous studies with BIT225 (N-carbamimidoyl-5-(1-methyl-1H-pyrazol-4-yl)-2-naphthamide) have demonstrated a unique antiviral activity that blocks the release of HIV-1 from monocyte-derived macrophages (MDM). An...

    Authors: Gabriela Khoury, Gary Ewart, Carolyn Luscombe, Michelle Miller and John Wilkinson

    Citation: AIDS Research and Therapy 2016 13:7

    Content type: Short report

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  8. Because of the shared mean of transmission, hepatitis B virus (HBV) is one of an important cause of co-morbidity and mortality in peoples living with HIV/AIDS. Hence, the aim of this study was to determine the...

    Authors: Letebrhan Weldemhret, Tsehaye Asmelash, Rashmi Belodu and Dawit Gebreegziabiher

    Citation: AIDS Research and Therapy 2016 13:6

    Content type: Research

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  9. Pre-Exposure Prophylaxis (PrEP) has shown high efficacy in preventing human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) in several large clinical trials, and more recently in “...

    Authors: Hyman M. Scott and Jeffrey D. Klausner

    Citation: AIDS Research and Therapy 2016 13:5

    Content type: Review

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  10. To estimate the adult prevalence of HIV among the adult population in Zambia and determine whether demographic characteristics were associated with being HIV positive.

    Authors: Pascalina Chanda-Kapata, Nathan Kapata, Eveline Klinkenberg, Ngosa William, Liwewe Mazyanga, Katoba Musukwa, Elizabeth Chizema Kawesha, Felix Masiye and Peter Mwaba

    Citation: AIDS Research and Therapy 2016 13:4

    Content type: Research

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  11. Since the first HIV-1 case in 1989, Hebei province has presented a clearly rising trend of HIV-1 prevalence, and HIV-1 genetic diversity has become the vital barrier to HIV prevention and control in this area....

    Authors: Xinli Lu, Cuiying Zhao, Wei Wang, Chenxi Nie, Yuqi Zhang, Hongru Zhao, Suliang Chen and Ze Cui

    Citation: AIDS Research and Therapy 2016 13:3

    Content type: Research

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  12. Rates of first antiretroviral therapy (cART) modifications are high in most observational studies. The age-related differences in treatment duration and characteristics of first cART modifications remain under...

    Authors: Justyna D. Kowalska, Joanna Kubicka, Ewa Siwak, Piotr Pulik, Ewa Firląg-Burkacka and Andrzej Horban

    Citation: AIDS Research and Therapy 2016 13:2

    Content type: Research

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  13. Novel fourth generation screening and confirmatory human immunodeficiency virus (HIV) assays are now commercially available and incorporated into new diagnostic algorithms. We report two cases involving a tota...

    Authors: Peter Liu, Patrick Jackson, Nathan Shaw and Scott Heysell

    Citation: AIDS Research and Therapy 2016 13:1

    Content type: Case report

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  14. This short report arose from a follow-up study of children previously diagnosed with human immunodeficiency virus (HIV) encephalopathy and spastic diplegia and is among the first to describe that increased low...

    Authors: Theresa N. Mann, Kirsten A. Donald, Kathleen G. Walker and Nelleke G. Langerak

    Citation: AIDS Research and Therapy 2015 12:43

    Content type: Short report

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  15. The risk of cardiovascular diseases (CVD) in human immunodeficiency virus (HIV) infected people on antiretroviral therapy (ART) from some rural parts of Africa is not well known. We assessed CVD risk factors, ...

    Authors: Felistas Mashinya, Marianne Alberts, Jean-Pierre Van geertruyden and Robert Colebunders

    Citation: AIDS Research and Therapy 2015 12:42

    Content type: Research

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  16. Late diagnosis and presentation to human immune deficiency virus (HIV)/acquired immune deficiency syndrome care reduce the benefits of antiretroviral therapy and increase the risk of HIV transmission.

    Authors: Yalemzewod Assefa Gelaw, Goitom Halefom Senbete, Akelew Awoke Adane and Kefyalew Addis Alene

    Citation: AIDS Research and Therapy 2015 12:40

    Content type: Research

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  17. An increasing number of patients in Africa are experiencing virologic failure on second-line antiretroviral therapy (ART) and those who develop resistance to protease inhibitors (PI) will require third-line A...

    Authors: Graeme Meintjes, Liezl Dunn, Marla Coetsee, Michael Hislop, Rory Leisegang, Leon Regensberg and Gary Maartens

    Citation: AIDS Research and Therapy 2015 12:39

    Content type: Research

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  18. Access to antiretroviral treatment (ART) in resource-limited countries has increased significantly but scaling-up ART into semi-rural and rural areas is more recent. Information on treatment outcome in such ar...

    Authors: Abla A. Konou, Mounerou Salou, Nicole Vidal, Pascal Kodah, Damobé Kombate, Pyabalo Kpanla, Tchabia Nabroulaba, Djifa Nyametso, Assétina Singo-Tokofaï, Palokinam Pitche, Eric Delaporte, Mireille Prince-David, Martine Peeters and Anoumou Y. Dagnra

    Citation: AIDS Research and Therapy 2015 12:38

    Content type: Short report

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  19. Community-drug distribution point is a care model for stable patients in the community designed to make ART delivery more efficient for the health system and provide appropriate support to encourage long-term ...

    Authors: Stephen Okoboi, Erin Ding, Steven Persuad, Jonathan Wangisi, Josephine Birungi, Susan Shurgold, Darius Kato, Maureen Nyonyintono, Aggrey Egessa, Celestin Bakanda, Paula Munderi, Pontiano Kaleebu and David M. Moore

    Citation: AIDS Research and Therapy 2015 12:37

    Content type: Research

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  20. The development of HIV related pulmonary arterial hypertension (PAH) reduces the probability of survival by half as compared with HIV-infected individuals without HIV related PAH. HIV infected patients have a ...

    Authors: Jean Joel R. Bigna, Paule Sandra D. Sime and Sinata Koulla-Shiro

    Citation: AIDS Research and Therapy 2015 12:36

    Content type: Review

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  21. Identifying those at increased risk of death during TB treatment is a priority in resource-constrained settings. We performed this study to determine predictors of mortality during TB treatment.

    Authors: Dominique J. Pepper, Michael Schomaker, Robert J. Wilkinson, Virginia de Azevedo and Gary Maartens

    Citation: AIDS Research and Therapy 2015 12:35

    Content type: Research

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  22. CCR5-using (r5) HIV-1 predominates during asymptomatic disease followed by occasional emergence of CXCR4-using (x4) or dual tropic (r5x4) virus. We examined the contribution of the x4 and r5 components to repl...

    Authors: Immaculate L Nankya, Denis M Tebit, Awet Abraha, Fred Kyeyune, Richard Gibson, Oyebisi Jegede, Gabrielle Nickel and Eric J Arts

    Citation: AIDS Research and Therapy 2015 12:34

    Content type: Research

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  23. Cryptococcal meningitis is one of the most lethal fungal infections in patients with acquired immune deficiency syndrome (AIDS). The incidence of and mortality from cryptococcal meningitis have markedly decrea...

    Authors: Hideki Hashimoto, Shuji Hatakeyama and Hiroshi Yotsuyanagi

    Citation: AIDS Research and Therapy 2015 12:33

    Content type: Case report

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  24. The objective of this study was to determine the rate of acquired immune deficiency syndrome (AIDS) in Zhejiang province and to identify specific factors associated with progression of this disease.

    Authors: Lin Chen, Jiezhe Yang, Renjie Zhang, Yun Xu, Jinlei Zheng, Jianmin Jiang, Jun Jiang, Lin He, Ning Wang, Philip Chun Yeung and Xiaohong Pan

    Citation: AIDS Research and Therapy 2015 12:32

    Content type: Research

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  25. We evaluated the effectiveness of darunavir (DRV) treatment plus an optimized background regimen in 120 HIV-1 treatment-experienced patients.

    Authors: José Antonio Mata-Marín, Gloria Huerta-García, Juan Carlos Domínguez-Hermosillo, Marcelino Chavez-García, Marco Isaac Banda-Lara, Nohemí Nuñez-Rodríguez, Javier Enrique Cruz-Herrera, Jorge Luis Sandoval-Ramírez, Ivan Martínez-Abarca, Alfredo Francisco Villagómez-Ruíz, Bulmaro Manjarrez-Tellez and Jesús Gaytán-Martínez

    Citation: AIDS Research and Therapy 2015 12:31

    Content type: Research

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  26. Protease inhibitors (PI)s have been associated with distal sensory polyneuropathy (DSP) and metabolic complications in high-income countries. No data exist in Africans where second-line antiretroviral therapy ...

    Authors: John-Randel Vermaak, Joel A. Dave, Naomi Levitt and Jeannine M. Heckmann

    Citation: AIDS Research and Therapy 2015 12:30

    Content type: Research

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  27. Alcohol consumption is prevalent amongst HIV positive population. Importantly, chronic alcohol use is reported to exacerbate HIV pathogenesis. Although alcohol is known to increase oxidative stress, especially...

    Authors: Anusha Ande, Namita Sinha, P. S. S. Rao, Carole P. McArthur, Leo Ayuk, Paul N. Achu, Annette Njinda, Anil Kumar and Santosh Kumar

    Citation: AIDS Research and Therapy 2015 12:29

    Content type: Research

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  28. Human leukocyte antigen (HLA)-B*5701 is strongly associated with developing a hypersensitivity reaction to abacavir (ABC). Limited data exist on HLA-B*5701 prevalence in HIV-1-infected subjects in China. We in...

    Authors: Hongwei Zhang, Tong Zhang, Hongxin Zhao, Ning Han, Haiwei Zhou, Yun He, Qingxia Zhao, Hong Li, Huiqin Li, Mi Zhang, Jianjian Li, Yongtao Sun, Ke Zhao, Qing Liu, Zhiying Liu, Zhen Li…

    Citation: AIDS Research and Therapy 2015 12:28

    Content type: Research

    Published on:

  29. Although injection drug use drives antiretroviral drug resistance, the prevalence of protease inhibitor (PI) resistance among Kenyan IDUs remains undetermined. We, therefore, explored PI resistance mutations a...

    Authors: Valentine Budambula, Francis O. Musumba, Mark K. Webale, Titus M. Kahiga, Francisca Ongecha-Owuor, James N. Kiarie, George A. Sowayi, Aabid A. Ahmed, Collins Ouma and Tom Were

    Citation: AIDS Research and Therapy 2015 12:27

    Content type: Research

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  30. HIV infected children experience a range of hematological complications which show marked improvement within 6 months of initiating anti-retroviral therapy. The Objectives of the study was to describe the chan...

    Authors: Elizabeth Gathoni Kibaru, Ruth Nduati, Dalton Wamalwa and Nyambura Kariuki

    Citation: AIDS Research and Therapy 2015 12:26

    Content type: Research

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  31. India has a large number of HIV infected patients being followed up at anti-retroviral therapy (ART) centers. The patients are regularly offered CD4 count estimation for deciding their eligibility for ART init...

    Authors: Ashwini Shete, Dharmesh P Singh, Bharati Mahajan, Amol Kokare, Ramesh Paranjape and Madhuri Thakar

    Citation: AIDS Research and Therapy 2015 12:25

    Content type: Research

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  32. A number of metabolic abnormalities, such as dysglycaemia, insulin resistance, lipodystrophy and dyslipidaemia, are associated with the use of antiretroviral drugs. We aimed to assess the effects of long-term ...

    Authors: Zulfa Abrahams, Joel A Dave, Gary Maartens and Naomi S Levitt

    Citation: AIDS Research and Therapy 2015 12:24

    Content type: Research

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  33. It is a challenge to differentiate between HIV-associated neurocognitive disorders (HAND) and other types of neurocognitive disease in the ageing HIV-infected population. Here we describe a 63 year old HIV-inf...

    Authors: Signar Mäkitalo, Åsa Mellgren, Ellen Borgh, Lena Kilander, Tobias Skillbäck, Henrik Zetterberg and Magnus Gisslén

    Citation: AIDS Research and Therapy 2015 12:23

    Content type: Case report

    Published on:

  34. In Henan, China, first-line antiretroviral treatment (ART) was implemented early in a large number of treatment-experienced patients who were more likely to have a drug resistance. Therefore, we investigated t...

    Authors: Jia Liu, Yasong Wu, Wenjie Yang, Xiujuan Xue, Guoqing Sun, Chunhua Liu, Suian Tian, Dingyong Sun, Qian Zhu and Zhe Wang

    Citation: AIDS Research and Therapy 2015 12:22

    Content type: Research

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  35. Lipodystrophy (LD) is a frequent adverse event of combination antiretroviral therapy (ART) and occurs mainly in patients exposed to first-generation antiretroviral drugs. The aim of this study was to explore a...

    Authors: Charlotte M Verolet, Cécile Delhumeau-Cartier, Marlène Sartori, Simona Toma, Sophie Zawadynski, Minerva Becker, Enos Bernasconi, Laurence Toutous Trellu and Alexandra Calmy

    Citation: AIDS Research and Therapy 2015 12:21

    Content type: Research

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  36. Trends in prevalence of opportunistic infections (OIs) associated with the human immunodeficiency virus (HIV) in resource poor settings have previously not been well documented. The objective of this study was...

    Authors: John Rubaihayo, Nazarius M Tumwesigye and Joseph Konde-Lule

    Citation: AIDS Research and Therapy 2015 12:20

    Content type: Research

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  37. Estimates of the interval from HIV-1 infection to disease progression may be affected by selection bias, and data concerning asymptomatic early seroconverters are limited. We examined the interval until diseas...

    Authors: Dai Watanabe, Sachiko Suzuki, Misa Ashida, Yuka Shimoji, Kazuyuki Hirota, Yoshihiko Ogawa, Keishiro Yajima, Daisuke Kasai, Yasuharu Nishida, Tomoko Uehira and Takuma Shirasaka

    Citation: AIDS Research and Therapy 2015 12:19

    Content type: Research

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  38. A 21 year old MSM patient with newly diagnosed HIV infection was hospitalized in our department after ingestion of an overdose of his antiretroviral therapy (ART) comprising dolutegravir (DTG - Tivicay®) and t...

    Authors: Marcel Lee, Florian Eyer, Norbert Felgenhauer, Hartwig HF Klinker and Christoph D Spinner

    Citation: AIDS Research and Therapy 2015 12:18

    Content type: Case report

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  39. To determine the levels of NT-pro BNP in HIV patients over 40 years who are receiving highly active antiretroviral therapy (HAART) and investigating potential independent clinical or laboratory factors.

    Authors: Julián Olalla, Elena Crespo, Javier De la Torre, Marco Sempere, Alfonso Del Arco, José Luis Prada, Rocío Malvarez, Javier Pérez and Javier García-Alegría

    Citation: AIDS Research and Therapy 2015 12:17

    Content type: Research

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  40. Sporotrichosis is an infection caused by a dimorphic fungus of the Sporothrix schenckii complex. Host immunity is an important factor in the clinical manifestations of the disease. Deeply immunocompromised indivi...

    Authors: Ariane Gomes Paixão, Maria Clara Gutierrez Galhardo, Rodrigo Almeida-Paes, Estevão Portela Nunes, Marcelo Luiz Carvalho Gonçalves, Gisele Larias Chequer and Cristiane da Cruz Lamas

    Citation: AIDS Research and Therapy 2015 12:16

    Content type: Case report

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  41. Codes of confidentiality play an essential role in the intimate discourses in many learned professions. Codes with various prescriptions exist. The Hippocratic Oath for example, prescribes rewards to the secre...

    Authors: Amos K Laar, Debra A DeBruin and Susan Craddock

    Citation: AIDS Research and Therapy 2015 12:15

    Content type: Research

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  42. Little evidence exists on the connections between nutrition, diet intake, and quality of life (QoL) among people living with HIV (PLHIV). The study aimed to estimate the prevalence of under-nutrition among PLH...

    Authors: Rajshree Thapa, Archana Amatya, Durga Prasad Pahari, Kiran Bam and M Sophia Newman

    Citation: AIDS Research and Therapy 2015 12:14

    Content type: Research

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  43. We report a rare case of osteonecrosis of the jaw following necrotizing gingivitis in a Japanese AIDS patient. Intraoral examination showed exposed necrotic bone in the left mandible and spontaneous loss of te...

    Authors: Yusuke Zushi, Kazuma Noguchi, Kuniyasu Moridera, Kazuki Takaoka and Hiromitsu Kishimoto

    Citation: AIDS Research and Therapy 2015 12:13

    Content type: Case report

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  44. New evidence has emerged regarding when to commence antiretroviral therapy (ART), optimal treatment regimens, management of HIV co-infection with opportunistic infections, and management of ART failure. The 20...

    Authors: Weerawat Manosuthi, Sumet Ongwandee, Sorakij Bhakeecheep, Manoon Leechawengwongs, Kiat Ruxrungtham, Praphan Phanuphak, Narin Hiransuthikul, Winai Ratanasuwan, Ploenchan Chetchotisakd, Woraphot Tantisiriwat, Sasisopin Kiertiburanakul, Anchalee Avihingsanon, Akechittra Sukkul and Thanomsak Anekthananon

    Citation: AIDS Research and Therapy 2015 12:12

    Content type: Review

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  45. An HIV-1 tropism test is recommended prior to CCR5 antagonist administration to exclude patients harboring non-R5 virus from treatment with this class of antiretrovirals. HIV-1 tropism determination based on p...

    Authors: Russell E Baumann, Amy A Rogers, Hasnah B Hamdan, Harold Burger, Barbara Weiser, Wei Gao, Kathryn Anastos, Mary Young, William A Meyer III, Rick L Pesano and Ron M Kagan

    Citation: AIDS Research and Therapy 2015 12:11

    Content type: Research

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  46. Polymorphisms in cytochrome P450 2B6 (CYP2B6) affect the steady state plasma concentration of nevirapine. CYP2B6 516G>T and 983T>C are common in African populations, but data on their influence on plasma nevir...

    Authors: Margaret Ngwono Oluka, Faith Apolot Okalebo, Anastasia Nkatha Guantai, R Scott McClelland and Susan M Graham

    Citation: AIDS Research and Therapy 2015 12:10

    Content type: Research

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  47. MDD and HIV/AIDS have a high prevalence worldwide with severe consequences for patients. In both conditions, compliance with treatment is key to successfully treat these disorders. In the current study, we exa...

    Authors: Francois N Slabbert, Brian H Harvey, Christiaan B Brink and Martie S Lubbe

    Citation: AIDS Research and Therapy 2015 12:9

    Content type: Research

    Published on: