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  1. Human T-cell leukemia virus type-1 (HTLV-1) induces adult T-cell leukemia/lymphoma (ATL/L), a fatal lymphoproliferative disorder, and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chro...

    Authors: Emmanuel Agbottah, Wen-I Yeh, Reem Berro, Zachary Klase, Caitlin Pedati, Kyleen Kehn-Hall, Weilin Wu and Fatah Kashanchi
    Citation: AIDS Research and Therapy 2008 5:12
  2. Human immunodeficiency virus type 1 (HIV-1)-based gene delivery systems are popular due to their superior efficiency of transduction of primary cells. However, these systems cannot be readily used for delivery...

    Authors: Narasimhachar Srinivasakumar
    Citation: AIDS Research and Therapy 2008 5:11
  3. Terpenoid derivatives originating from many plants species, are interesting compounds with numerous biological effects, such as anti-HIV-1 activity. The zinc tetra-ascorbo-camphorate complex (or "C14"), a new ...

    Authors: Héla Saïdi, Mohammad-Ali Jenabian, Bernard Gombert, Charlotte Charpentier, Aurèle Mannarini and Laurent Bélec
    Citation: AIDS Research and Therapy 2008 5:10
  4. Immune restoration disease (IRD) is an adverse consequence of antiretroviral therapy, where the restored pathogen-specific response causes immunopathology. Mycobacteria are the pathogens that most frequently p...

    Authors: Andrew Lim, Lloyd D'Orsogna, Patricia Price and Martyn A French
    Citation: AIDS Research and Therapy 2008 5:9
  5. Human immunodeficiency virus type 1 (HIV-1) infection and the consequent acquired immunodeficiency syndrome (AIDS) has protean manifestations, including muscle wasting and cardiomyopathy, which contribute to i...

    Authors: Jeffrey S Otis, Yaroslav I Ashikhmin, Lou AnnS Brown and David M Guidot
    Citation: AIDS Research and Therapy 2008 5:8
  6. According to Vietnamese policy, HIV-infected women should have access at least to HIV testing and Nevirapine prophylaxis, or where available, to adequate counselling, HIV infection staging, ARV prophylaxis, an...

    Authors: Thu Anh Nguyen, Pauline Oosterhoff, Yen Pham Ngoc, Pamela Wright and Anita Hardon
    Citation: AIDS Research and Therapy 2008 5:7
  7. Although Venezuela has a National Human Immunodeficiency Virus (HIV) Program offering free diagnosis and treatment, 41% of patients present for diagnosis at a later disease-stage, indicating that access to car...

    Authors: Maeva A Bonjour, Morelba Montagne, Martha Zambrano, Gloria Molina, Catherine Lippuner, Francis G Wadskier, Milvida Castrillo, Renzo N Incani and Adriana Tami
    Citation: AIDS Research and Therapy 2008 5:6
  8. Once-daily (QD) ritonavir 100 mg-boosted fosamprenavir 1400 mg (FPV/r100) or atazanavir 300 mg (ATV/r100), plus tenofovir/emtricitabine (TDF/FTC) 300 mg/200 mg, have not been compared as initial antiretroviral...

    Authors: Kimberly Y Smith, Winkler G Weinberg, Edwin DeJesus, Margaret A Fischl, Qiming Liao, Lisa L Ross, Gary E Pakes, Keith A Pappa and CTracey Lancaster
    Citation: AIDS Research and Therapy 2008 5:5
  9. In a routine service delivery setting in Uganda, we assessed the ability of the WHO clinical stage to accurately identify HIV-infected patients in whom antiretroviral therapy should be started.

    Authors: Shabbar Jaffar, Josephine Birungi, Heiner Grosskurth, Barbara Amuron, Geoffrey Namara, Christine Nabiryo and Alex Coutinho
    Citation: AIDS Research and Therapy 2008 5:4
  10. Kaposi Sarcoma (KS) is a multifocal angioproliferative neoplasm characterized by inflammation, oedema, neoangiogenesis and spindle cell proliferation. The pathogenesis of human immunodeficiency virus (HIV)-ass...

    Authors: L Feller, JN Masipa, NH Wood, EJ Raubenheimer and J Lemmer
    Citation: AIDS Research and Therapy 2008 5:2
  11. Gut immune components are severely compromised among persons with AIDS, which allows increased translocation of bacterial lipopolysaccharides (LPS) into the systemic circulation. These microbial LPS are report...

    Authors: Esaki Muthu Shankar, Ramachandran Vignesh, Kailapuri G Murugavel, Pachamuthu Balakrishnan, Ramalingam Sekar, Charmaine AC Lloyd, Suniti Solomon and Nagalingeswaran Kumarasamy
    Citation: AIDS Research and Therapy 2007 4:29
  12. As HIV treatment is scaled-up in resource-poor settings, the timely identification of persons with HIV infection remains an important challenge. Most people with HIV are unaware of their status, and those who ...

    Authors: Louise C Ivers, Kenneth A Freedberg and Joia S Mukherjee
    Citation: AIDS Research and Therapy 2007 4:28
  13. The objective of this study was to examine missed opportunities for participation in a prevention of mother-to-child transmission (PMTCT) programme in three sites in South Africa. A rapid anthropological asses...

    Authors: Lungiswa L Nkonki, Tanya M Doherty, Zelee Hill, Mickey Chopra, Nikki Schaay and Carl Kendall
    Citation: AIDS Research and Therapy 2007 4:27
  14. Non-nucleoside reverse transcriptase inhibitor (NNRTI) with stavudine and lamivudine is widely used as the first-line antiretroviral therapy (ART) in resource-limited settings. Lipodystrophy is common and opti...

    Authors: Somnuek Sungkanuparph, Sasisopin Kiertiburanakul, Anucha Apisarnthanarak, Kumthorn Malathum, Siriorn Watcharananan and Boonmee Sathapatayavongs
    Citation: AIDS Research and Therapy 2007 4:26
  15. Epidemiologic studies indicate that bacterial vaginosis (BV), a common alteration of lower genital tract flora in women, is associated with increased susceptibility to HIV infection. Other recent studies show ...

    Authors: Gregory T Spear, Elizabeth St John and MReza Zariffard
    Citation: AIDS Research and Therapy 2007 4:25
  16. Internal polymerase III promoters in retroviral vectors have been used extensively to express short RNA sequences, such as ribozymes, RNA aptamers or short interfering RNA inhibitors, in various positions and ...

    Authors: Stephen E Braun, Xuanling Shi, Gang Qiu, Fay Eng Wong, Pheroze J Joshi, Vinayaka R Prasad and RPaul Johnson
    Citation: AIDS Research and Therapy 2007 4:24
  17. Monitoring dynamics in HIV-1 infection and risk behaviours is important in evaluating, adjusting and scaling up prevention programmes. The objective of this study was to estimate trends in the prevalence of HI...

    Authors: Elia J Mmbaga, Akhtar Hussain, Germana H Leyna, Carol Holm-Hansen, Kagoma S Mnyika, Noel E Sam, Elise Klouman and Knut-Inge Klepp
    Citation: AIDS Research and Therapy 2007 4:23
  18. HIV/AIDS incidence and mortality rates have decreased in the U.S. since 1996. Accompanying the longer life spans of those diagnosed with the disease, however, is a tremendous rise in expenditures on medication...

    Authors: Yonghua Jing, Patricia Klein, Christina ML Kelton, Xing Li and Jeff J Guo
    Citation: AIDS Research and Therapy 2007 4:22
  19. Penicillium marneffei is a dimorphic fungus, endemic in South-east Asia. The fungus causes severe disease in immunocompromised patients such as AIDS. However, no case of immune restoration disease of Penicillium ...

    Authors: Swati Gupta, Purva Mathur, Dipesh Maskey, Naveet Wig and Sarman Singh
    Citation: AIDS Research and Therapy 2007 4:21
  20. When on the market, microbicides are likely to be used by individuals who do not know their HIV status. Hence, assessment of safety and acceptability among HIV positive men and women is important. Acceptabilit...

    Authors: Gita Ramjee, Neetha S Morar, Sarah Braunstein, Barbara Friedland, Heidi Jones and Janneke van de Wijgert
    Citation: AIDS Research and Therapy 2007 4:20
  21. The introduction of HAART has initially improved the quality of life (QoL) of HIV-positive (HIV+) patients, however body fat redistribution (BFR) and metabolic disorders associated with long-term HAART use may...

    Authors: Eugene Mutimura, Aimee Stewart and Nigel J Crowther
    Citation: AIDS Research and Therapy 2007 4:19
  22. It is critical to understand the pattern of antiretroviral treatment (ART) prescription in different regions of the world as ART procurement needs to be anticipated. We aimed at exploring rates and predictors ...

    Authors: Preeyaporn Srasuebkul, Alexandra Calmy, Jialun Zhou, Nagalingeswaran Kumarasamy, Matthew Law and Poh Lian Lim
    Citation: AIDS Research and Therapy 2007 4:18
  23. Diagnosis of an opportunistic illness (OI) in a person with HIV infection is a sentinel event, indicating opportunities for improving diagnosis of HIV infection and secondary prevention efforts. In the past, r...

    Authors: Patrick S Sullivan, Maxine Denniston, AD McNaghten, Susan E Buskin, Stephanie T Broyles and Eve D Mokotoff
    Citation: AIDS Research and Therapy 2007 4:17
  24. A segment of the HIV infected population develops abnormal and excessive accumulation of adipose tissue in the trunk, including accumulation of visceral (deep abdominal) adipose tissue. This condition, known a...

    Authors: Kenneth Lichtenstein, Ashok Balasubramanyam, Rajagopal Sekhar and Eric Freedland
    Citation: AIDS Research and Therapy 2007 4:16
  25. Although the introduction of combined therapy with reverse transcriptase and protease inhibitors has resulted in considerable decrease in HIV related mortality; it has also induced the development of multiple ...

    Authors: Amisha Malhotra, Sunanda Gaur, Patricia Whitley-Williams, Caitlin Loomis and Anna Petrova
    Citation: AIDS Research and Therapy 2007 4:15
  26. Human immunodeficiency virus (HIV)-associated adipose redistribution syndrome (HARS) is a fat accumulation disorder characterized by increases in visceral adipose tissue. Patients with HARS may also present wi...

    Authors: Kenneth Lichtenstein, Ashok Balasubramanyam, Rajagopal Sekhar and Eric Freedland
    Citation: AIDS Research and Therapy 2007 4:14
  27. A severely immune-suppressed AIDS patient was suspected of suffering from BK virus (BKV) meningoencephalitis, after being studied for common causes of neurological complications of co-infectious origin. Polyme...

    Authors: José E Vidal, Maria C Fink, Filiberto Cedeno-Laurent, Serena Delbue, Pasquale Ferrante, Rafi F Dauar, Francisco Bonasser Filho, Roberta Schiavon Nogueira, Eduardo E Calore, Claudio S Pannuti, J Roberto Trujillo and Augusto C Penalva de Oliveira
    Citation: AIDS Research and Therapy 2007 4:13
  28. Sustained use of antiretroviral therapy has been consistently shown to be one of the primary predictors of long-term effectiveness. Switching and discontinuation reflect patient and provider decisions that may...

    Authors: John D Morris, Elizabeth T Golub, Shruti H Mehta, Lisa P Jacobson and Stephen J Gange
    Citation: AIDS Research and Therapy 2007 4:12
  29. During the extended clinically latent period associated with Human Immunodeficiency Virus (HIV) infection the virus itself is far from latent. This phase of infection generally comes to an end with the develop...

    Authors: Simone E Langford, Jintanat Ananworanich and David A Cooper
    Citation: AIDS Research and Therapy 2007 4:11
  30. The immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients initiating antiretroviral therapy (ART) results from restored immunity to specific infectious or non-infectious antigens. A parad...

    Authors: David M Murdoch, Willem DF Venter, Annelies Van Rie and Charles Feldman
    Citation: AIDS Research and Therapy 2007 4:9
  31. Protease inhibitors, as part of highly active anti-retroviral therapy (HAART), have significantly increased the lifespan of human immunodeficiency virus (HIV) infected patients. Several deleterious side effect...

    Authors: Melinda E Wilson, Kimberly F Allred, Elizabeth M Kordik, Deana K Jasper, Amanda N Rosewell and Anthony J Bisotti
    Citation: AIDS Research and Therapy 2007 4:8
  32. The promise of microbicides as an HIV prevention method will not be realized if not supported by health care providers. They are the primary source of sexual health information for potential users, in both the...

    Authors: Gita Ramjee, Neetha S Morar, James Mtimkulu, Joanne E Mantell and Varanna Gharbaharan
    Citation: AIDS Research and Therapy 2007 4:7
  33. Antiretroviral therapy (ART) with a generic fixed-dose combination (FDC) of stavudine (d4T)/lamivudine (3TC)/nevirapine (NVP) is widely used in developing countries. The clinical data of this FDC among very ad...

    Authors: Weerawat Manosuthi, Sukanya Chimsuntorn, Sirirat Likanonsakul and Somnuek Sungkanuparph
    Citation: AIDS Research and Therapy 2007 4:6
  34. A case of a 15 year old girl with retroviral rebound syndrome after discontinuation of highly active antiretroviral treatment (HAART) due to side effects is presented. The patient was transmitted with HIV at b...

    Authors: Vanda Friman and Magnus Gisslén
    Citation: AIDS Research and Therapy 2007 4:3
  35. The association between baseline drug resistance mutations and subsequent increase in viral failure has not been established for HIV-infected children. We evaluated drug resistance mutations at 39 codon sites ...

    Authors: Susan A Fiscus, Andrea Kovacs, Leslie A Petch, Chengcheng Hu, Andrew A Wiznia, Lynne M Mofenson, Ram Yogev, Kenneth McIntosh, Stephen I Pelton, Sonia Napravnik, Kenneth Stanley and Sharon A Nachman
    Citation: AIDS Research and Therapy 2007 4:2
  36. CD4+ T lymphocyte (CD4) cell count testing is the standard method for determining eligibility for antiretroviral therapy (ART), but is not widely available in sub-Saharan Africa. Total lymphocyte counts (TLCs)...

    Authors: David M Moore, Anna Awor, Robert S Downing, Willy Were, Peter Solberg, David Tu, Keith Chan, Robert S Hogg and Jonathan Mermin
    Citation: AIDS Research and Therapy 2007 4:1
  37. We evaluated whether FLAVORx helped thirty Thai children take opened capsule, crushed tablets and liquid generic ARVs with more ease. All children had excellent adherence, evaluated by PACTG Standard Internati...

    Authors: Torsak Bunupuradah, Siripan Wannachai, Arpa Chuamchaitrakool, Jintana Intasan, Thantip Nuchapong, Woodie Neiss, Kenny Kramm, Chitsanu Pancharoen, David Burger and Jintanat Ananworanich
    Citation: AIDS Research and Therapy 2006 3:30
  38. A 4-week, uninterrupted treatment with 9-(2-phosphonyl-methoxypropyly)adenine (PMPA, commonly called tenofovir) completely prevents simian immunodeficiency virus (SIVmne) infection in cynomolgus macaques if treat...

    Authors: Peter Emau, Yonghou Jiang, Michael B Agy, Baoping Tian, Girma Bekele and Che-Chung Tsai
    Citation: AIDS Research and Therapy 2006 3:29
  39. HLA-G gene is a non-classical MHC class 1 molecule that is highly expressed in the trophoblast at the maternal-fetal interface. In an attempt to elucidate possible immunological mechanisms facilitating protection...

    Authors: Felix O Aikhionbare, K Kumaresan, Falah Shamsa and Vincent C Bond
    Citation: AIDS Research and Therapy 2006 3:28
  40. Women continue to be disproportionately affected by HIV in Tanzania, and factors contributing to this situation need to be identified. The objective of this study was to determine social, behavioral and biolog...

    Authors: Sia E Msuya, Elizabeth Mbizvo, Akhtar Hussain, Jacqueline Uriyo, Noel E Sam and Babill Stray-Pedersen
    Citation: AIDS Research and Therapy 2006 3:27
  41. The CD4+ T cell count estimation is an important monitoring tool for HIV disease progression and efficacy of anti-retroviral treatment (ART). Due to availability of ART at low cost in developing countries, que...

    Authors: Madhuri R Thakar, Kishore B Kumar, Bharati A Mahajan, Sanjay M Mehendale and Ramesh S Paranjape
    Citation: AIDS Research and Therapy 2006 3:26
  42. Current HIV/AIDS statistics show that women account for almost 60% of HIV infections in Sub-Saharan Africa. HIV prevention tools such as male and female condoms, abstinence and monogamy are not always feasible...

    Authors: Gita Ramjee, Robin Shattock, Sinead Delany, Ian McGowan, Neetha Morar and Megan Gottemoeller
    Citation: AIDS Research and Therapy 2006 3:25
  43. Despite multiple sexual exposure to HIV-1 virus, some individuals remain HIV-1 seronegative (exposed seronegative, ESN). The mechanisms underlying this resistance remain still unclear, although a multifactoria...

    Authors: Enrico M Trecarichi, Mario Tumbarello, Katleen de Gaetano Donati, Enrica Tamburrini, Roberto Cauda, Christina Brahe and Francesco D Tiziano
    Citation: AIDS Research and Therapy 2006 3:22