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  1. There is limited evidence on the modification or stopping of antiretroviral therapy (ART) regimens, including novel antiretroviral drugs. The aim of this study was to evaluate the discontinuation of first ART ...

    Authors: Volkan Korten, Deniz Gökengin, Gülhan Eren, Taner Yıldırmak, Serap Gencer, Haluk Eraksoy, Dilara Inan, Figen Kaptan, Başak Dokuzoğuz, Ilkay Karaoğlan, Ayşe Willke, Mehmet Gönen and Önder Ergönül
    Citation: AIDS Research and Therapy 2021 18:4
  2. Pediatric tuberculosis (TB), human immunodeficiency virus (HIV), and TB-HIV co-infection are health problems with evidence-based diagnostic and treatment algorithms that can reduce morbidity and mortality. Imp...

    Authors: W. Chris Buck, Hanh Nguyen, Mariana Siapka, Lopa Basu, Jessica Greenberg Cowan, Maria Inês De Deus, Megan Gleason, Ferreira Ferreira, Carla Xavier, Benedita Jose, Criménia Muthemba, Beatriz Simione and Peter Kerndt
    Citation: AIDS Research and Therapy 2021 18:3
  3. Pre-exposure prophylaxis (PrEP) for HIV is instrumental in the prevention of HIV for HIV-uninfected persons, by drastically reducing the risk of acquisition in the case of high-risk exposures. Despite its demo...

    Authors: Marie Bistoquet, Alain Makinson, Vincent Tribout, Cyril Perrollaz, Gérard Bourrel, Jacques Reynes and Agnès Oude Engberink
    Citation: AIDS Research and Therapy 2021 18:2
  4. South Africa, with one of the highest HIV prevalences in the world, introduced the universal test and treat (UTT) programme in September 2016. Barriers to sustained viral suppression may include drug resistanc...

    Authors: Pascal O. Bessong, Nontokozo D. Matume and Denis M. Tebit
    Citation: AIDS Research and Therapy 2021 18:1
  5. Diagnosis of people living with HIV (PLHIV) is the first step toward achieving the new Fast Track Strategy to end AIDS by 2030: 95-95-95. However, reaching PLHIV is especially difficult in resource-limited set...

    Authors: Mohammad Pour, Linda James, Kamlendra Singh, Samuel Mampunza, Franklin Baer, JoAnna Scott, Michael G. Berg, Mary A. Rodgers, Gavin A. Cloherty, John Hackett Jr and Carole P. McArthur
    Citation: AIDS Research and Therapy 2020 17:67
  6. With increased use of antiretroviral therapy (ART), HIV mortality rates are declining and people living with HIV (PLWH) are surviving longer. We characterized CD4 recovery and viral suppression among adults ag...

    Authors: Emmanuel Bahemana, Allahna Esber, Nicole Dear, Kavitha Ganesan, Ajay Parikh, Domonique Reed, Lucas Maganga, Samoel Khamadi, Mucho Mizinduko, Anange Lwilla, Dorothy Mkondoo, Gwamaka Mwaisanga, Nancy Somi, John Owouth, Jonah Maswai, Francis Kiweewa…
    Citation: AIDS Research and Therapy 2020 17:66
  7. Analytical treatment interruptions (ATI) are commonly used clinical endpoints to assess interventions aimed at curing HIV or achieving antiretroviral therapy (ART)-free HIV remission. Understanding the accepta...

    Authors: Jillian S. Y. Lau, Miranda Z. Smith, Brent Allan, Cipriano Martinez, Jennifer Power, Sharon R. Lewin and James H. McMahon
    Citation: AIDS Research and Therapy 2020 17:65
  8. A substantial number of persons living with HIV (PLWH) in Nigeria do not experience durable viral suppression on first-line antiretroviral therapy (ART). Understanding risk factors for first-line treatment fai...

    Authors: Nicaise Ndembi, Fati Murtala-Ibrahim, Monday Tola, Jibreel Jumare, Ahmad Aliyu, Peter Alabi, Charles Mensah, Alash’le Abimiku, Miguel E. Quiñones-Mateu, Trevor A. Crowell, Soo-Yon Rhee, Robert W. Shafer, Ravindra Gupta, William Blattner, Manhattan E. Charurat and Patrick Dakum
    Citation: AIDS Research and Therapy 2020 17:64
  9. Tuberculosis (Tb) is the most frequent opportunistic infection among people living with HIV infection. The impact of Tb co-infection in the establishment and maintenance of the HIV reservoir is unclear.

    Authors: Jingna Xun, Tangkai Qi, Lei Zou, Qi Tang, Yinzhong Shen, Junyang Yang, Luman Xie, Yongjia Ji, Renfang Zhang, Li Liu, Jiangrong Wang, Corky Steinhart, Zhenyan Wang, Yang Tang, Wei Song, Jianjun Sun…
    Citation: AIDS Research and Therapy 2020 17:63
  10. Improved point-of-care diagnostic tests for tuberculosis (TB) in severe immune suppressed people living with HIV (PLWH) are needed to decrease morbidity and mortality outcomes. The aim of the study is to evalu...

    Authors: Juan Ignacio García, Johanna Meléndez, Rosa Álvarez, Carlos Mejía-Chew, Holden V. Kelley, Sabeen Sidiki, Alejandra Castillo, Claudia Mazariegos, Cesar López-Téllez, Diana Forno, Nancy Ayala, Joan-Miquel Balada-Llasat, Carlos Rodolfo Mejía-Villatoro, Shu-Hua Wang, Jordi B. Torrelles and Janet Ikeda
    Citation: AIDS Research and Therapy 2020 17:62

    The Correction to this article has been published in AIDS Research and Therapy 2022 19:48

  11. Although HIV-related deaths have decreased dramatically following the introduction of antiretroviral therapy (ART), HIV infection itself causes increased morbidity and mortality for both non-AIDS-related event...

    Authors: Martina Maritati, Trentini Alessandro, Nunzia Zanotta, Manola Comar, Tiziana Bellini, Laura Sighinolfi and Carlo Contini
    Citation: AIDS Research and Therapy 2020 17:61
  12. Rapid antiretroviral therapy (ART), ideally initiated within twenty-four hours of diagnosis, may be crucial in efforts to increase virologic suppression and reduce HIV transmission. Recent studies, including d...

    Authors: Courtney E. Sims Gomillia, Kandis V. Backus, James B. Brock, Sandra C. Melvin, Jason J. Parham and Leandro A. Mena
    Citation: AIDS Research and Therapy 2020 17:60
  13. During the COVID-19 pandemic, hospitals faced increasing pressure, where people living with HIV risked to either acquire SARS-CoV-2 and to interrupt the HIV continuum of care.

    Authors: Eugenia Quiros-Roldan, Paola Magro, Canio Carriero, Annacarla Chiesa, Issa El Hamad, Elena Tratta, Raffaella Fazio, Beatrice Formenti and Francesco Castelli
    Citation: AIDS Research and Therapy 2020 17:59
  14. AIDS-related KS generally involves cutaneous lesions, that slowly progress over months to years. Neither rapidly progressing of KS nor KS complicated with hemophagocytic syndrome (HPS) has rarely been reported.

    Authors: Pingzheng Mo, Liping Deng, Xiaoping Chen, Yong Xiong and Yongxi Zhang
    Citation: AIDS Research and Therapy 2020 17:58
  15. Real-time medication monitoring (RTMM) may potentially enhance adherence to antiretroviral treatment (ART). We describe a participant in an ongoing trial who, shortly after completing trial participation, died...

    Authors: Kennedy Michael Ngowi, Lydia Masika, Furaha Lyamuya, Eva Muro, Blandina T. Mmbaga, Mirjam A. G. Sprangers, Pythia T. Nieuwkerk, Rob E. Aarnoutse, Peter Reiss and I. Marion Sumari-de Boer
    Citation: AIDS Research and Therapy 2020 17:57
  16. HIV Self-Testing (HIVST) is universally accepted as an innovative strategy complimenting existing HIV testing services to archive the UNAIDS, 95-95-95 goals by 2030. However, the adoption of HIVST is lagging i...

    Authors: Proches Arobogast Vara, Luyeye Sostenes Buhulula, Fatma Aziz Mohammed and Bernard Njau
    Citation: AIDS Research and Therapy 2020 17:56
  17. Adolescent girls and young women (AGYW) remain disproportionately affected by HIV. In a rural area of South Africa with an annual incidence (2011–2015) of 5 and 7% per annum for 15–19 and 20–24-year olds respe...

    Authors: Sarah E Nakasone, Natsayi Chimbindi, Nondumiso Mthiyane, Busisiwe Nkosi, Thembelihle Zuma, Kathy Baisley, Jaco Dreyer, Deenan Pillay, Sian Floyd, Isolde Birdthistle, Janet Seeley and Maryam Shahmanesh
    Citation: AIDS Research and Therapy 2020 17:55
  18. Cytomegalovirus (CMV) is among the most common opportunistic infections identified in patients with HIV/AIDS. CMV often targets the colon in such patients. However, the role of regulatory T cells (Tregs) and Prog...

    Authors: Lei Sun, Kun Yang, Liang Zhang, Li-ming Qi, Jia-min Chen, Ping Li, Jiang Xiao, Hong-xin Zhao and Peng Wang
    Citation: AIDS Research and Therapy 2020 17:54
  19. In the context of scaling the viral load in resource limited settings, following HIV infected patient’s adults and children with CD4+ T-lymphocyte count still very important in settings where the decentralizat...

    Authors: Bertrand Sagnia, Fabrice Mbakop Ghomsi, Ana Gutierrez, Samuel Sosso, Rachel Kamgaing, Aubin Joseph Nanfack, Nadesh Nji, Georgia Ambada, Abel Lissom, Thibaut Flaurant Tchouangueu, Loveline Ngu Ndengkoh, Irenée Domkam, Godwin Nchinda and Alexis Ndjolo
    Citation: AIDS Research and Therapy 2020 17:53
  20. Hemophagocytic lymphohistiocytosis syndrome (HLS) is an immune-mediated life-threatening disease considered as a medical emergency, with a potentially fatal multisystem inflammatory outcome. We present a patie...

    Authors: Luz A. González-Hernández, Monserrat Alvarez-Zavala, Rodolfo I. Cabrera-Silva, Pedro Martínez-Ayala, Fernando Amador-Lara, Aída S. Ramírez-González, Ana L. Ron-Magaña, Vida V. Ruiz Herrera, Karina Sánchez-Reyes and Jaime F. Andrade-Villanueva
    Citation: AIDS Research and Therapy 2020 17:52
  21. The key cause of HIV transmission is failure to provide adequate information about HIV/AIDS which is a substantial public health issue in low and middle-income countries. While global health coverage continues...

    Authors: Chilot Desta Agegnehu, Bisrat Misganaw Geremew, Malede Mequanent Sisay, Kindie Fentahun Muchie, Zinash Teferu Engida, Temesgen Worku Gudayu, Daniel Sisay Weldetsadik and Alemneh Mekuriaw Liyew
    Citation: AIDS Research and Therapy 2020 17:51
  22. Real-time, objective measures of adherence to antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) are needed to better assess adherence levels and to expedite clinical response for those with subo...

    Authors: Ashley R. Bardon, Jane M. Simoni, Leif M. Layman, Joanne D. Stekler and Paul K. Drain
    Citation: AIDS Research and Therapy 2020 17:50
  23. In resource poor countries like Ethiopia, little is known about the survival of patients treated with antiretroviral therapy which depends on different factors. Evidence shows that mortality has been high part...

    Authors: Abewa Kebede, Fasil Tessema, Gadisa Bekele, Zerihun Kura and Hailu Merga
    Citation: AIDS Research and Therapy 2020 17:49
  24. In Sub-Saharan Africa where HIV disproportionately affects women, heterosexual male sex workers (HMSW) and their female clients are at risk of acquiring or transmitting HIV and other STIs. However, few studies...

    Authors: Richard Muhindo, Andrew Mujugira, Barbara Castelnuovo, Nelson K. Sewankambo, Rosalind Parkes-Ratanshi, Juliet Kiguli, Nazarius Mbona Tumwesigye and Edith Nakku-Joloba
    Citation: AIDS Research and Therapy 2020 17:48
  25. It is well known that people living with HIV (PLWH) is in higher risk for the development of depression and it has also been suggested that the use of efavirenz into the antiretroviral regimens increases even ...

    Authors: Alejandro Checa, Alberto Castillo, Malena Camacho, William Tapia, Isabel Hernandez and Enrique Teran
    Citation: AIDS Research and Therapy 2020 17:47
  26. The COVID-19 has been a severe pandemic all around the world. Nowadays the patient with co-infection of HIV and SARS-CoV-2 was rarely reported. Here we reported a special case with HIV and SARS-CoV-2 co-infect...

    Authors: Wu Menghua, Zheng Xin, Liu Jianwei, Zhang Yu and Yao Qinwei
    Citation: AIDS Research and Therapy 2020 17:46
  27. The aim of this study was to investigate the effectiveness and tolerability of the combination elvitegravir/cobicistat/tenofovir/emtricitabine plus darunavir (EVG/COB/TFV/FTC + DRV) in treatment-experienced pa...

    Authors: Inés Suárez-García, Cristina Moreno, Marta Ruiz-Algueró, María Jesús Pérez-Elías, Marta Navarro, Marcos Díez Martínez, Pompeyo Viciana, Laura Pérez-Martínez, Miguel Górgolas, Concha Amador, Miguel Alberto de Zárraga and Inma Jarrín
    Citation: AIDS Research and Therapy 2020 17:45
  28. To evaluate the impact of AIDS-defining events (ADE) on long-term mortality of HIV positive individuals on antiretroviral therapy (ART), a retrospective HIV/AIDS treatment cohort study performed in Southwester...

    Authors: Yunxuan Huang, Oulu Zhou, Zhigang Zheng, Yuexiang Xu, Yi Shao, Chunwei Qin, Fengxiang Qin, Jingzhen Lai, Huifang Liu, Rongfeng Chen, Li Ye, Hao Liang, Xionglin Qin and Junjun Jiang
    Citation: AIDS Research and Therapy 2020 17:44
  29. Early detection of viremia in HIV infected patients on anti-retroviral therapy (ART) is important to prevent disease progression as well as accumulation of drug resistance mutations. This makes HIV viral load ...

    Authors: Ashwini Shete, Sampada Dhayarkar, Ashwini Dhamanage, Smita Kulkarni, Manisha Ghate, Shashikala Sangle, Uttam Medhe, Vinita Verma, Shobini Rajan, Toshio Hattori and Raman Gangakhedkar
    Citation: AIDS Research and Therapy 2020 17:43
  30. HIV status disclosure facilitates receipt of HIV prevention and treatment services. Although disclosure to sexual partners, family members or friends has been extensively studied, disclosure to community-based...

    Authors: John Charles, Amon Exavery, Asheri Barankena, Erica Kuhlik, Godfrey M. Mubyazi, Ramadhani Abdul, Alison Koler, Levina Kikoyo and Elizabeth Jere
    Citation: AIDS Research and Therapy 2020 17:42
  31. In pregnancy, reduction of HIV plasma viral load (pVL) for the prevention of vertical transmission is time-constrained. The study primary objective is to investigate factors associated with faster initial HIV ...

    Authors: Jasmini Alagaratnam, Helen Peters, Kate Francis, Natasha Kay, Yvonne Gilleece, Fionnuala P. Finnerty, Rosanna E. Grimes, Sarah Parry, Mags Portman, Brenton C. Wait, Rimi Shah, Sherie Roedling, David A. Hawkins, Sarah Chitty, Liat Sarner, Rebecca Marcus…
    Citation: AIDS Research and Therapy 2020 17:41
  32. The US President’s Emergency Plan for AIDS Relief (PEPFAR) was launched to increase access to antiretroviral treatment (ART) among people living with HIV (PLHIV) and to prevent new HIV infections globally. As ...

    Authors: Andrew T. Boyd, Ikwo Oboho, Heather Paulin, Hammad Ali, Catherine Godfrey, Anand Date and J. Sean Cavanaugh
    Citation: AIDS Research and Therapy 2020 17:40
  33. Antiretroviral treatment has played a pivotal role in the reduction of HIV/AIDS-related morbidity and mortality. However, treatment options can be impaired by the development of antiretroviral treatment failur...

    Authors: Jemberu Nega, Solomon Taye, Yihenew Million, Chaturaka Rodrigo and Setegn Eshetie
    Citation: AIDS Research and Therapy 2020 17:39
  34. Vacuolar encephalomyelopathy, a disregarded diagnosis lately, was a major neurological disease in the terminal stages of human immunodeficiency virus (HIV)-1 infection in the pre-antiretroviral therapy (ART) e...

    Authors: Kazumasa Akagi, Kazuko Yamamoto, Asuka Umemura, Shotaro Ide, Tatsuro Hirayama, Takahiro Takazono, Yoshifumi Imamura, Taiga Miyazaki, Noriho Sakamoto, Hirokazu Shiraishi, Hideaki Takahata, Yoshiaki Zaizen, Junya Fukuoka, Minoru Morikawa, Kazuto Ashizawa, Katsuji Teruya…
    Citation: AIDS Research and Therapy 2020 17:38
  35. The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individ...

    Authors: Vijay Harypursat, Yihong Zhou, Shengquan Tang and Yaokai Chen
    Citation: AIDS Research and Therapy 2020 17:37
  36. The link between food insecurity and depression in people living with HIV/AIDS (PLWHA) has been explored in numerous studies; however, the existing evidence is inconclusive due to inconsistent results. Therefo...

    Authors: Getinet Ayano, Light Tsegay and Melat Solomon
    Citation: AIDS Research and Therapy 2020 17:36
  37. Adolescents living with HIV (ALHIV) in Malawi experience multiple challenges associated with their illness and various social, environmental, economic and cultural factors. In exploring their various medical c...

    Authors: Blessings N. Kaunda-Khangamwa, Prosperina Kapwata, Kennedy Malisita, Alister Munthali, Effie Chipeta, Sam Phiri and Lenore Manderson
    Citation: AIDS Research and Therapy 2020 17:35
  38. Long acting and permanent contraceptive methods by far are the most effective, very safe and convenient methods than short acting contraceptive methods. But in less developed countries, use of long acting reve...

    Authors: Betselot Yirsaw, Feleke Gebremeskel, Gebrekiros Gebremichael and Tewoderos Shitemaw
    Citation: AIDS Research and Therapy 2020 17:34
  39. Female sex workers (FSW) are considered a key group for HIV transmissions in sub-Saharan Africa. The HIV Care Continuum and HIV drug resistance (HIVDR) among FSW has not been well studied in most countries in ...

    Authors: Jacob Lindman, Mamadu Aliu Djalo, Ansu Biai, Fredrik Månsson, Joakim Esbjörnsson, Marianne Jansson, Patrik Medstrand and Hans Norrgren
    Citation: AIDS Research and Therapy 2020 17:33
  40. Door-to-door distribution of HIV self-testing kits (HIVST) has the potential to increase uptake of HIV testing services (HTS). However, very few studies have explored the social response to and implications of...

    Authors: Chiti Bwalya, Musonda Simwinga, Bernadette Hensen, Lwiindi Gwanu, Able Hang’andu, Chama Mulubwa, Mwelwa Phiri, Richard Hayes, Sarah Fidler, Alwyn Mwinga, Helen Ayles and Virginia Bond
    Citation: AIDS Research and Therapy 2020 17:32
  41. In the era of “test and treat strategy”, CD4 testing remains an important tool for monitoring HIV-infected individuals. Since conventional methods of CD4 count measurement are costly and cumbersome, POC CD4 co...

    Authors: Elmir Elharti, Halima Abbadi, Rajae Bensghir, Kamal Marhoum El Filali, Hajar Elmrabet and Hicham Oumzil
    Citation: AIDS Research and Therapy 2020 17:31
  42. Despite initial high motivation, individuals receiving antiretroviral therapy (ART) for several years may experience incomplete adherence over time, increasing their risk of HIV-related morbidity and mortality...

    Authors: Larissa Jennings Mayo-Wilson, Bianca Devoto, Jessica Coleman, Barbara Mukasa, Angela Shelton, Sarah MacCarthy, Uzaib Saya, Harriet Chemusto and Sebastian Linnemayr
    Citation: AIDS Research and Therapy 2020 17:30
  43. This study aimed to investigate the measures of retention in care (RIC) in persons living with HIV (PLWH) and type 2 diabetes mellitus (T2DM) by age group (younger vs. older adults).

    Authors: Julie Ann Zuniga, Alexandra A. García, Junse Lee and Jungmin Park
    Citation: AIDS Research and Therapy 2020 17:29
  44. Tuberculosis (TB) and human immunodeficiency virus (HIV) co-infection constitute a deadly infectious disease synergy disease and major public health problem throughout the world. The risk of developing active ...

    Authors: Simon Sensalire, Esther Karungi Karamagi Nkolo, Juliana Nabwire, Anna Lawino, Dithan Kiragga, Martin Muhire, Herbert Kadama, Cordelia Katureebe, Proscovia Namuwenge, Joshua Musinguzi, Jacqueline Calnan and Dejene Seyoum
    Citation: AIDS Research and Therapy 2020 17:28
  45. The pressing need to expand the biomedical HIV prevention evidence base during pregnancy is now increasingly recognized. Women’s views regarding participation in such trials and initiating PrEP while pregnant ...

    Authors: Kristen Sullivan, Tiwonge Mtande, Elana Jaffe, Nora Rosenberg, Chifundo Zimba, Irving Hoffman, Maggie Little, Ruth Faden and Anne Drapkin Lyerly
    Citation: AIDS Research and Therapy 2020 17:27
  46. The clinical and laboratory characteristics of AIDS-associated Talaromyces marneffei infection, a rare but a fatal mycosis disease of the central nervous system, remain unclear.

    Authors: Yu-Ye Li, Rong-Jing Dong, Samip Shrestha, Pratishtha Upadhyay, Hui-Qin Li, Yi-Qun Kuang, Xin-Ping Yang and Yun-Gui Zhang
    Citation: AIDS Research and Therapy 2020 17:26
  47. Metabolic complications in human immunodeficiency virus (HIV)-infected individuals are common. Prediabetes represents a high risk for future diabetes development. This study aimed to determine the prevalence, ...

    Authors: Angsana Phuphuakrat, Hataikarn Nimitphong, Sirimon Reutrakul and Somnuek Sungkanuparph
    Citation: AIDS Research and Therapy 2020 17:25
  48. To explore the use of illicit drugs by people living with HIV (PLHIV) taking antiretroviral therapy (ART) and their relationship with variables relevant to the management of HIV infection, such as knowledge an...

    Authors: María José Fuster-RuizdeApodaca, Vanessa Castro-Granell, Ana Laguía, Ángeles Jaén, Santiago Cenoz and María José Galindo
    Citation: AIDS Research and Therapy 2020 17:24
  49. The anti-retroviral combination of abacavir/lamivudine plus rilpivirine (ABC/3TC/RPV) is not recommended by international guidelines as the first-line regimen. However, it is potent, well-tolerated, and afford...

    Authors: Sharlene Ho, Joshua Guoxian Wong, Oon Tek Ng, Cheng Chuan Lee, Yee Sin Leo, David Chien Boon Lye and Chen Seong Wong
    Citation: AIDS Research and Therapy 2020 17:23
  50. Pre-treatment drug resistance (PDR) among antiretroviral drug-naïve people living with HIV (PLHIV) represents an important indicator for the risk of treatment failure and the spread of drug resistant HIV varia...

    Authors: F. Neuhann, A. de Forest, E. Heger, A. Nhlema, C. Scheller, R. Kaiser, H. M. Steffen, H. Tweya, G. Fätkenheuer and S. Phiri
    Citation: AIDS Research and Therapy 2020 17:22