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Table 1 Demographic characteristics, immunization status, and preventative behaviour practices among a cohort of people living with HIV in Canada; the total cohort (n = 375) is separated into four overlapping groups with the aim of answering four questions as listed in footnote 1

From: Preventative behaviours and COVID-19 infection in a Canadian cohort of people living with HIV

Characteristics

Does previous known COVID-19 infection influence preventative behaviours?(n = 351)

Is participant multimorbidity associated with preventative behaviours?1

(n = 341)

Are preventative behaviours, living in a crowded space, and working in close proximity to others associated with COVID-19 infection?1

(n = 326)

Are preventative behaviours and/or uptake of vaccination associated with symptomatic infection during Omicron?1

(n = 283)

Age in years, mean (SD)

52.0 (13.5)

51.9 (13.4)

52.0 (13.6)

52.3 (13.5)

Current sex, n (%)

    

 Male

260 (74.1)

257 (75.4)

245 (75.2)

216 (76.3)

 Female

89 (25.4)

82 (24.0)

79 (24.2)

65 (23.0)

 Prefer to self-describe

2 (0.6)

2 (0.6)

2 (0.6)

2 (0.7)

Self-declared race or ethnicity, n (%)

    

 White

196 (56.5)

197 (58.5)

193 (59.8)

172 (61.2)

 Black

71 (20.5)

66 (19.6)

59 (18.3)

48 (17.1)

 Asian

31 (8.8)

29 (8.5)

27 (8.3)

22 (7.8)

 Latin American

27 (7.7)

24 (7.0)

24 (7.4)

21 (7.4)

 Indigenous

6 (1.7)

6 (1.8)

5 (1.5)

5 (1.8)

 Other

19 (5.4)

18 (5.3)

18 (5.5)

16 (5.7)

 No response

4 (1.1)

4 (1.2)

3 (0.9)

2 (0.7)

Time of enrolment based on COVID-19 waves, n (%)

    

 April–May 2021 (Alpha)

89 (25.4)

83 (24.3)

85 (26.1)

73 (25.8)

 June–July 2021 (Alpha/Delta)

109 (31.1)

115 (33.7)

104 (31.9)

88 (31.1)

 August–September 2021 (Delta)

82 (23.4)

74 (21.7)

73 (22.4)

65 (23.0)

 October–November 2021 (Delta)

53 (15.1)

50 (14.7)

48 (14.7)

43 (15.2)

 December 2021–January 2022 (Omicron BA.1)

18 (5.1)

19 (5.6)

16 (4.9)

14 (4.9)

Duration of HIV infection in years, median (IQR)

16.0 (7.0–24.0)

16.0 (7.0–25.0)

16.0 (7.0–25.0)

17.0 (7.0–24.5)

HIV controlled and stable2, n/total n available (%)

169/326 (51.8)

171/323 (52.9)

161/301 (53.5)

143/263 (54.4)

Immune non-responders3, n/total n available (%)

29/331 (8.8)

29/322 (9.0)

27/307 (8.8)

23/267 (8.6)

Comorbidities

    

 Two or more comorbidities, n/total n available (%)

97/344 (28.2)

95/341 (27.9)

89/319 (27.9)

76/277 (27.4)

 Obesity, n/total n available (%)

74/331 (22.4)

74/325 (22.8)

66/307 (21.5)

54/268 (20.1)

 Cardiac disease (including hypertension), n (%)

66 (18.8)

62 (18.1)

60 (18.4)

54 (19.0)

 Dyslipidemia, n (%)

47 (13.6)

45 (13.2)

43 (13.4)

40 (14.3)

 Chronic lung disease, n (%)

30 (8.7)

30 (8.8)

27 (8.4)

23 (8.2)

 Diabetes, n (%)

26 (7.5)

26 (7.6)

24 (7.5)

23 (8.2)

 Other, n (%)

105 (29.9)

102 (29.9)

97 (29.7)

83 (29.3)

Highest level of education, n (%)

    

 Less than or including secondary school/trade certificate, apprenticeship, non-university certificate or diploma from a community college, CEGEP

212 (63.5)

208 (64.0)

196 (63.0)

168 (62.2)

 University undergraduate degree or graduate degree

122 (36.5)

117 (36.0)

115 (37.0)

102 (37.8)

 Prefer not to answer/no response

17

16

15

13

COVID-19 infection prior to enrolment, n (%)

    

 Self-reported

25 (7.1)

n/a

n/a

n/a

 By antibody testing only

n/a

24 (7.0)

n/a

n/a

COVID-19 infection after enrolment, n (%)

    

 Self-reported

54 (15.4)

54 (15.8)

54 (16.6)

51 (18.0)

 By antibody testing only

34 (9.7)

34 (10.0)

34 (10.4)

n/a

Sought testing for COVID-19 infection prior to enrolment, n/total n available (%)

120/342 (35.1)

98/332 (29.5)

95/317 (30.0)

87/276 (31.5)

Number of COVID-19 vaccine doses received prior to study enrolment, n (%)

    

 None

95 (27.1)

88 (25.8)

87 (26.7)

69 (24.4)

 Received 1 dose of a 2-dose schedule

130 (37.0)

130 (38.1)

121 (37.1)

105 (37.1)

 Received 2 doses of a 2-dose schedule, or 1 dose of a 1-dose schedule

126 (35.9)

123 (36.1)

118 (36.2)

109 (38.5)

 At least 3 doses of COVID-19 vaccine received by Dec. 1, 2021, n (%)

58 (16.5)

55 (16.1)

56 (17.2)

52 (18.4)

 At least 4 doses of COVID-19 vaccine received by Sept. 1, 2022, n (%)

76 (21.7)

73 (21.4)

74 (22.7)

66 (23.3)

 Participants reporting usually getting influenza immunization, n/total n available (%)

259/341 (76.0)

251/332 (75.6)

241/317 (76.0)

215/276 (77.9)

Number of individuals (including participant) living in household, n (%)

    

 Unknown

15

16

15

11

 One

163 (48.5)

158 (48.6)

153 (49.2)

132 (48.5)

 Two or more

173 (51.5)

167 (51.4)

158 (50.8)

140 (51.5)

 At least one bedroom in household per person, n/total n available (%)

267/330 (80.9)

261/319 (81.8)

251/305 (82.3)

219/267 (82.0)

 At least one bathroom in household per person, n/total n available (%)

214/328 (65.2)

212/317 (66.9)

204/303 (67.3)

177/265 (66.8)

 Traveled outside of home province since January 2020, n/total n available (%)

82/342 (24.0)

79/331 (23.9)

77/317 (24.3)

69/275 (25.1)

 Paid or unpaid work in close physical proximity to other people, n/total n available (%)

109/339 (32.2)

103/327 (31.5)

100/316 (31.6)

92/276 (33.3)

 Participants attending at least one gathering of ten or more since March 2020, n/total n available (%)

130/318 (40.9)

126/309 (40.8)

120/298 (40.3)

110/262 (42.0)

 

Does previous known COVID-19 infection influence preventative behaviours?4

Is participant multimorbidity associated with preventative behaviours?5

Are preventative behaviours, living in a crowded space, and working in close proximity to others associated with COVID-19 infection?6

Are preventative behaviours and/or uptake of vaccination associated with symptomatic infection during Omicron?7

Answer to numbered question

No

(n = 326)

Yes

(n = 25)

No

(n = 246)

Yes

(n = 95)

No

(n = 238)

Yes

(n = 88)

No

(n = 232)

Yes

(n = 51)

Preventative behaviours, % practising behaviours

        

 Wearing a mask in public places

86.8 (277/319)

84 (21/25)

86.4 (209/242)

92.3 (84/91)

86.1 (199/231)

88.6 (78/88)

85.8 (194/226)

90.2 (46/51)

 Practicing physical distancing in public places

78.3 (249/318)

84 (21/25)

75.5 (182/241)

85.7 (78/91)*

79.1 (182/230)

76.1 (67/88)

79.1 (178/225)

76.5 (39/51)

 Avoiding crowded places/gatherings

70.3 (233/317)

60 (15/25)

67.9 (163/240)

76.9 (70/91)

72.1 (165/229)

65.9 (58/88)

71.4 (160/224)

64.7 (33/51)

 Avoiding common greetings

68.3 (218/319)

76 (19/25)

65.3 (158/242)

75.8 (69/91)

71.0 (164/231)

61.4 (54/88)

70.8 (160/226)

62.7 (32/51)

 Limiting contact with people at higher risk

64.5 (187/290)

69.6 (16/23)

65 (141/217)

63.5 (54/85)

64.0 (135/211)

65.8 (52/79)

64.1 (132/206)

63.8 (30/47)

 Self-isolating because the participant thought infected with COVID-19

32.5 (82/252)

56.5 (13/23)*

33.7 (64/190)

26.8 (19/71)

27.9 (50/179)

43.8 (32/73)*

27.3 (48/176)

50.0 (22/44)*

Self-quarantining because the participant thought exposed to COVID-19 but showed no symptoms

23.4 (60/256)

65.0 (13/20)*

26.6 (51/192)

18.1 (13/72)

20.3 (37/182)

31.1 (23/74)

(35/179)

(13/44)

  1. 1The four questions are as follows: (1) Does previous known COVID-19 infection (excluding those with positive antibody testing but no knowledge of prior infection) influence preventative behaviours?, (2) Is participant multimorbidity associated with preventative behaviour practices?, (3) Are preventative behaviour practices, living in a crowded space, and working in close proximity to others associated with COVID-19 infection?, and (4) Are preventative behaviour practices and/or uptake of COVID-19 vaccination associated with developing symptomatic COVID-19 infection during the highly contagious Omicron wave?
  2. 2HIV controlled and stable defined by CD4 cell count ≥ 350, suppressed HIV viral load, and ≤ 1 comorbidity
  3. 3Immune non-responders defined by CD4 < 350 and CD4/CD8 < 0.75 despite suppressed HIV viral load
  4. 4Effect of previous known COVID-19 infection on preventative behaviours: 24 were excluded from the analysis as they reported not having COVID-19 infection prior to study enrolment but had positive antibody testing
  5. 5Effect of multimorbidity on preventative behaviours: 25 were excluded from the analysis for this question as they had self-reported COVID-19 infection prior to enrolment; we hypothesized this would affect their decision-making regarding preventative behaviours
  6. 6Preventative behaviours and COVID-19 infection risk: 49 were excluded from the analysis for this question as they had either self-reported COVID-19 infection prior to enrolment or positive antibody testing at the time of enrolment
  7. 7Preventative behaviours and Omicron infection risk: 92 were excluded from the analysis; 57 had COVID-19 infection before study enrolment or before the Omicron wave, 29 had asymptomatic COVID-19 during the Omicron wave (positive antibody testing but did not self-report infection), and 6 dropped out from the study prior to the Omicron wave
  8. * denotes p ≤ 0.05