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Table 2 Factors related to HBV infection among HIV-infected patients on ART at Mekelle hospital in northern Ethiopia in the bivariate and multivariate logistic regression analysis (n = 439)

From: Hepatitis B and C viral coinfections and their association with HIV viral load suppression among HIV-1 infected patients on ART at Mekelle hospital, northern Ethiopia

Characteristic

HIV-HBV coinfection

COR (95% CI)

P

value

AOR (95% CI)

P value

Yes (n = 44)

No (n = 395)

    

n (%)

n (%)

    

Gender

 Male

17 (10.9)

138 (89.1)

1.17 (0.62–2.23)

0.62

–

 

 Female

27 (9.5)

257 (90.5)

Ref

   

Age group in years

 3–18

2 (6.7)

28 (96.7)

Ref

   

 19–35

7 (7.9)

82 (92.1)

1.19 (0.23 -6.09)

0.82

–

 

 36–52

25 (10.7)

208 (89.3)

1.68 (0.38–7.49)

0.68

–

 

≥ 53

9 (10.3)

78 (89.7)

1.61 (0.33–7.93)

0.55

–

 

Educational level*

 Primary education

16 (9.3)

157 (90.7)

2.65 (0.59–11.9)

0.21

3.15 (0.51–19.4)

0.22

 Secondary education

3 (3.5)

83 (96.5)

0.94 (0.15–5.81)

0.97

0.75 (0.072–7.84)

0.81

 Illiterate

23 (18.3)

103 (81.7)

5.81 (1.32–25.5)

0.02

6.57 (1.04–41.6)

0.04

 Tertiary education

2 (3.9)

49 (96.1)

Ref

 

Ref

 

Marital status#

 Married

13 (8.1)

149 (91.9)

0.84 (0.32–2.19)

0.72

–

 

 Divorced

12 (16)

73 (84)

1.75 (0.64–4.53)

0.28

–

 

 Widowed

11 (12.8)

75 (87.2)

1.41 (0.51–3.83)

0.51

–

 

 Single

7 (9.4)

67 (90.6)

Ref

   

ART adherence level

 Poor

5 (14.7)

29 (85.3)

1.58 (0.57–4.37)

0.37

–

 

 Fair

7 (8.9)

72 (91.1)

0.89 (0.37–2.11)

0.79

–

 

 Good

32 (9.8)

294 (90.2)

Ref

   

History of STIs

 Yes

16 (58.6)

41 (41.4)

4.93 (2.46–9.87)

 < 0.001

4.44 (1.31–15.0)

0.041

 No

28 (7.3)

354 (92.7)

Ref

 

Ref

 

Tattoo use

 Yes

11 (11.8)

69 (86.2)

1.58 (0.35–7.10)

0.26

–

 

 No

33 (9.2)

326 (90.8)

Ref

   

Baseline CD4 count (cells/ul)

  < 200

34 (30.3)

78 (69.7)

7.19 (1.63–31.6)

0.009

18.79 (2.18–161)

0.008

 201–500

6 (2.5)

230 (97.5)

0.43 (0.083–2.22)

0.31

0.78 (0.086–7.18)

0.83

≥ 501

2 (3.5)

54 (96.5)

0.61 (0.082–4.54)

0.63

2.13 (0.15–29.7)

0.57

 Test & treat

2 (5.7)

33 (94.3)

Ref

 

Ref

 

History of multiple sexual partners

 Yes

16 (51.6)

15 (48.4)

16.3 (6.80–38.9)

0.001

29.9 (7.82–114.8)

 < 0.0001

 No

28 (6.8)

380 (93.2)

Ref

 

Re

 
  1. AOR adjusted odds ratio, ART anti-retroviral therapy, COR crude odds ratio, CI confidence interval, HBV hepatitis B virus, HIV human immune deficiency virus, Ref reference, STIs sexually transmitted infections, WHO world health organization;
  2. *participants with non-applicable educational status were excluded from this analysis (n = 3); # = participants with non-applicable marital status were excluded from this analysis (n = 32)