Predicting viral load suppression by self-reported adherence, pharmacy refill counts and real time medication monitoring among people living with HIV in Tanzania

Ngowi, Kennedy M.; Minja, Linda; Boer, I. Marion Sumari-de; Aarnoutse, Rob E.; Masika, Lyidia; Sprangers, Mirjam A. G.; Pima, Francis M.; Mmbaga, Blandina T.; Reiss, Peter; Nieuwkerk, Pythia T.

doi:10.1186/s12981-022-00475-y

Table 7 Logistic regression models showing ART regimen and gender at different adherence cut-offs predicting detectable viral load at cut-off of ≥ 20 copies/ml

From: Predicting viral load suppression by self-reported adherence, pharmacy refill counts and real time medication monitoring among people living with HIV in Tanzania

Viral load ≥ 20 copies/ml			AOR (95%CI)	P
Self-report ≥ 80%	TLE		0.4(0.2–0.9)	0.019
	Other regimens	Ref	1	0.019
	Female		0.8(0.4–1.5)	0.5
	Male	Ref	1	0.5
Pharmacy refill ≥ 80%	TLE		0.4 (0.2–0.8)	0.012
	Other regimens	Ref	1	0.012
	Female		0.8(0.5–1.6)	0.6
	Male	Ref	1	0.6
RTMM ≥ 80%	TLE		0.2(0.06–0.8)	0.025
	Other regimens	Ref	1	0.025
	Female		0.7(0.25–2.2)	0.59
	Male	Ref	1	0.59
Self-report ≥ 85%	TLE		0.4(0.2–0.8)	0.011
	Other regimens	Ref	1	0.011
	Female		0.11(0.12–1.02)	0.65
	Male	Ref	1	0.65
Pharmacy refill ≥ 85%	TLE		0.4(0.2–0.8)	0.014
	Other regimens	Ref	1	0.014
	Female		0.77(0.4–1.5)	0.622
	Male	Ref	1	0.622
RTMM ≥ 85%	TLE		0.22(0.06–0.84)	0.03
	Other regimens	Ref	1	0.03
	Female		0.7(0.25–1.97)	0.54
	Male	Ref	1	0.54
Self-report ≥ 90%	TLE		0.4(0.2–0.8)	0.011
	Other regimens	Ref	1	0.011
	Female		0.9(0.46–1.6)	0.65
	Male	Ref	1	0.65
Pharmacy refill ≥ 90%	TLE		0.4(0.2–0.8)	0.014
	Other regimens	Ref	1	0.014
	Female		0.85(0.46–1.6)	0.63
	Male	Ref	1	0.63
RTMM ≥ 90%	TLE		0.1(0.06–0.84)	0.028
	Other regimens	Ref	1	0.028
	Female		0.7(0.2–2.04)	0.52
	Male	Ref	1	0.52
Self-report ≥ 95%	TLE		0.2(0.2–0.8)	0.008
	Other regimens	Ref	1	0.008
	Female		0.9 (0.5–1.65)	0.7
	Male	Ref	1	0.7
Pharmacy refill ≥ 95%	TLE		0.3(0.2–0.9)	0.017
	Other regimens	Ref	1	0.017
	Female		0.9 (0.5–1.7)	0.72
	Male	Ref	1	0.72
RTMM ≥ 95%	TLE		0.2 (0.06–0.8)	0.024
	Other regimens	Ref	1	0.024
	Female		0.68 (0.24–1.9)	0.5
	Male	Ref	1	0.5
Self-report 100%	TLE		0.3 (0.2–0.8)	0.007
	Other regimens	Ref	1	0.007
	Female		0.87 (0.5–1.6)	0.7
	Male	Ref	1	0.7
Pharmacy refill 100%	TLE		0.4(0.2–0.8)	0.01
	Other regimens	Ref	1	0.01
	Female		0.8(0.47–1.64)	0.7
	Male	Ref	1	0.7
RTMM 100%	TLE		0.2(0.05–0.8)	0.025
	Other regimens	Ref	1	0.025
	Female		0.68(0.2–1.97)	0.48
	Male	Ref	1	0.48

TLE Tenofovir/Lamivudine/Efavirenz.
Other regimen: ABC abacavir, ATV atazanavir, AZT zidovudine, FTC emtricitabine, IQR interquartile range, LPV lopinavir, NPV nevirapine, r ritonavir, DTG dolutegravir, Ref reference category.

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ISSN: 1742-6405

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