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Table 2 Types of AEs in patients with HIV and concomitant CRC according to antiviral regimens (n = 66)

From: Safety and efficacy of pharmacotherapy containing INSTIs and chemotherapy drugs in people living with HIV and concomitant colorectal cancer

AEs

DTG/3TC/TDF (group I) n = 20

DTG/ABT (group II) n = 24

BIC/TAF/FTC (group III) n = 22

P value

Any grade

grade 3-5

Any grade

Grade 3-5

Any grade

Grade 3-5

Neutropenia

19

1

21

1

16

1

0.129

Anemia

4

0

3

1

7

0

0.284

Thrombocytopenia

2

0

1

0

1

0

0.672

Peripheral neurotoxicity

13

0

11

0

11

0

0.421

Fever

1

0

1

0

0

0

Infection

0

0

0

0

1

0

Hypersensitivity

0

0

1

0

0

0

Liver function damage

0

0

1

0

3

0

Renal Impairment

1

0

1

0

0

0

Nausea

20

1

24

0

22

1

Vomiting

2

1

2

0

3

0

0.884

Diarrhea

0

0

0

0

1

0

Impaired cardiac function

0

0

2

0

0

0

  1. AEs = Adverse events
  2. CRC = Colorectal cancer
  3. DTG/3TC/TDF = dolutegravir/lamivudine/tenofovir
  4. DTG/ABT = dolutegravir/albuvirtide
  5. BIC/TAF/FTC = bictegravir/tenofovir alafenamide/emtricitabine
  6. P value meant statistical difference of AEs in any grade among the three groups