Prevalence of herpes simplex virus 2 among MSM in Mainland China: a systematic review and meta-synthesis

Table 3 Results of Meta-regression analysis for prevalence of HSV-2 among MSM in mainland China

Covariate	Meta-regression coefficient	95%CI	P value
Area
Central China [24, 42, 44] (Ref.^a)
Eastern China [25,26,28,31,33,36,37,39,40,49,51,52]	0.016	− 0.124 to 0.155	0.825
Southwest China [10, 32, 43, 45, 50]	0.047	− 0.111 to 0.204	0.562
Southern China [9, 29, 34, 38, 41]	0.007	− 0.151 to 0.165	0.932
Northeast China [30, 48]	− 0.023	− 0.222 to 0.177	0.824
Northern China [35]	− 0.068	− 0.315 to 0.179	0.590
Northwest China [46]	− 0.08	− 0.332 to 0.172	0.533
Multi-region [27, 47]	0.046	− 0.149 to 0.241	0.644
Study period
2000–2010 [10, 24, 29, 31, 32, 34, 38, 39, 45, 47, 52](Ref.)
2011–2020 [9,25,26,27,30,33,36,37,40,41,42,43,−44,49,50,−51]	− 0.037	− 0.117 to 0.043	0.367
Mixed [28, 35, 46, 48]	0.019	− 0.137 to 0.099	0.755
Sampling procedure
Multiple [24,25,27,29,34,35,36,43,49,51 ,52](Ref.)
Snowball [10, 32, 37, 38, 42, 45,46,47]	− 0.028	− 0.118 to 0.063	0.546
Venue-based [26, 31, 39]	0.028	− 0.103 to 0.158	0.679
Respondent-driven [28, 44, 50]	− 0.028	− 0.153 to 0.098	0.667
VCT [30, 33, 40]	− 0.152	− 0.282 to − 0.022	0.022
Time-location sampling [9]	0.074	− 0.125 to 0.272	0.467
STD clinic [41, 48]	− 0.049	− 0.198 to 0.099	0.512
Study design
Cohort [38, 46, 51](Ref.)
Cross-sectional [9,10,24,24,26,27,28,29,30,31,32,33,34,35,36,−37,39,40,41,42,43,44,45,47,48,49,−50,52]	− 0.023	− 0.146 to 0.099	0.713
QATSO
Good [9, 10, 25, 27, 28, 38, 40, 42, 46, 52](Ref.)
Satisfactory [24,26,29,30,31,32,33,34,35,36,37,39,41,43,44,45,47,48,49,50,−51]	− 0.062	− 0.136 to 0.013	0.106

ISSN: 1742-6405