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Table 2 Subgroup analysis of prevalence of HSV-2 among MSM in mainland China

From: Prevalence of herpes simplex virus 2 among MSM in Mainland China: a systematic review and meta-synthesis

Category

Subgroup

NO. of Studies

Prevalence

(95%CI)

N

I2(%)

P-value

for between groups

Area

Central China [24, 42, 44]

3

0.087(0.031–0.168)

1755

96

< 0.01

 

Eastern China[25, 26,28,31,33,36, 37,39 ,40,49,51,52]

12

0.095(0.068–0.126)

5912

92

 
 

Southwest China [10, 32, 43, 45, 50]

5

0.115(0.053–0.198)

2657

97.5

 
 

Southern China [9, 29, 34, 38, 41]

5

0.09(0.037–0.163)

5140

98.7

 
 

Northeast China [30, 48]

2

0.072(0–0.306)

490

97.8

 
 

Northern China [35]

1

0.053(0.04–0.069)

962

-

 
 

Northwest China [46]

1

0.047(0.026–0.077)

300

-

 
 

Multi-region [27, 47]

2

0.116(0.098–0.135)

7642

83.8

 

Study period

2000–2010[10, 24, 29, 31, 32, 34, 38, 39, 45, 47, 52]

11

0.106(0.072–0.145)

8067

94.9

0.65

 

2011–2020 [9,25,26,27,30,33,36,37,40,41,42,43,−44,49,50,−51]

16

0.085(0.058–0.117)

14,203

96.9

 
 

Mixed [28, 35, 46, 48]

4

0.096(0.044–0.164)

2588

95.6

 

Sampling procedure

Multiple [24, 25,27,29,34,35,36,43,49,51,52]

11

0.107(0.08–0.138)

10,134

93.3

< 0.01

 

Snowball[10, 32, 37, 38, 42, 45,46,47]

8

0.091(0.053–0.138)

7207

96.3

 
 

Venue-based [26, 31, 39]

3

0.124(0.062–0.204)

811

89.1

 
 

Respondent-driven [28, 44, 50]

3

0.091(0.032–0.176)

2058

96.3

 
 

VCT [30, 33, 40]

3

0.032(0.01–0.065)

1042

78.6

 
 

Time-location sampling [9]

1

0.158(0.141–0.176)

1695

-

 
 

STD clinic [41, 48]

2

0.081(0–0.292)

1911

98.8

 

Study Design

Cohort [38, 46, 51]

3

0.106(0.045–0.188)

961

92.7

0.71

 

Cross-sectional [9,10,24,25,26,27,28,29,30,31,32,33,34,35,36,−37,39,40,41,42,43,44,45,47,48,49,−50,52]

28

0.092(0.071–0.116)

23,897

96.4

 

QATSO

Good [9, 10, 25, 27, 28, 38, 40, 42, 46, 52]

10

0.119(0.086–0.157)

9773

93.6

0.08

 

Satisfactory [24,26,29,30,31,32,33,34,35,36,37,39,41,43,44,45,47,48,49,50, –51]

21

0.082(0.059–0.109)

15,085

96.2

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