Determinants and reasons for switching anti-retroviral regimen among HIV-infected youth in a large township of South Africa (2002–2019)

Table 1 Baseline characteristics of young people living with HIV accessing HIV care services at the Hannan Crusaid Treatment Centre in Cape town South Africa (2002–2019)

Variable	Sub category	Total sample		Never switched		Switched		p-value
Variable	Sub category	n = 2,061	Percent	n = 1,456	Percent	n = 605	Percent	p-value
Sex	Male	216	10.5	129	59.7	87	40.3	< 0.001
Sex	Female	1,845	89.5	1,327	71.9	518	28.1
Age (years)	10–17	212	10.3	115	54.3	97	45.7	< 0.001
Age (years)	18–24	1,849	89.7	1,341	72.5	508	27.5
WHO stage	l	1,213	58.9	1,008	83.1	205	16.9	< 0.001
	lll	318	15.4	205	64.5	113	35.5
	lll	390	18.9	177	45.4	213	54.6
	lV	140	6.8	66	47.1	74	2.9
ART status at entry into the clinic	Naive	2,032	98.6	1,435	70.6	597	29.4	0.833
ART status at entry into the clinic	Experienced	29	1.4	21	72.4	8	27.6
Transfer status into HCTC from another clinic	Not transferred	1,643	79.7	1,114	67.8	529	32.2	< 0.001
Transfer status into HCTC from another clinic	Transferred in	418	20.3	342	81.8	76	18.2
Baseline CD4	< 250	1,073	52.1	577	53.8	496	46.2	< 0.001
	250–499	775	37.6	680	87.7	95	12.3
	500 +	213	10.3	199	93.4	14	6.6
Year of ART initiation	Before 2010	457	22.2	168	36.8	289	63.2	< 0.001
Year of ART initiation	2010 +	1,604	77.8	1,288	80.3	316	19.7
NNRTI/PI based	NVP	239	11.6	87	36.4	152	63.6	< 0.001
	EFV	1,771	85.9	1,347	76.1	424	23.9
	LPV/r	48	2.3	21	43.7	27	56.3
	ATV/r	3	0.2	1	33.3	2	66.7

ISSN: 1742-6405