Fig. 1

An example used the nomogram to predict the occurrence of paradoxical IRIS in 6 months and 12 months. The predictive nomogram consists of HGB, CRP, increase in CD4 cell counts, age, and initial ART time. This patient was 20 years old, CRP of 14.5 mg/L, HGB of 111 g/L, who initiated ART within 4 weeks after antifungal treatment and increased in CD4 cell counts lower than four-folds. According to the nomogram, the total score of this patient added up to 283, suggesting the probability of paradoxical CM-IRIS in 6 months and 12 months was 0.613 and 0.754, respectively