Barriers to and enablers of uptake of antiretroviral therapy in integrated HIV and tuberculosis treatment programmes in sub-Saharan Africa: a systematic review and meta-analysis

Kadia, Benjamin Momo; Dimala, Christian Akem; Fongwen, Noah T.; Smith, Adrian D.

doi:10.1186/s12981-021-00395-3

Table 3 Quality appraisal of studies with quantitative estimates of outcomes

From: Barriers to and enablers of uptake of antiretroviral therapy in integrated HIV and tuberculosis treatment programmes in sub-Saharan Africa: a systematic review and meta-analysis

Study	Clear research question(s)/ objectives	Clearly defined study population	Participation rate ≥ 50%	Selection from same population	Justified sample size and study power	Exposures measured prior to outcomes	Reasonable timeframe for effect	Different levels of exposure	Clearly defined exposure measures	Repeated measure of exposure	Clearly defined outcomes	Blinded outcome assessors	Loss to follow-up ≤ 20%	Measured and adjusted confounders	Overall rating
Burnett, 2018	Yes	Yes	No	No	Yes	Yes	Yes	Yes	Yes	No	Yes	Can’t tell	No	Yes	Moderate
Ferroussier, 2013	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Gasana, 2008	No	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	No	Can’t tell	Yes	No	Moderate
Harris, 2008	No	Yes	Yes	No	Yes	Yes	Yes	No	Yes	No	No	Can’t tell	No	No	Moderate
Shaffer, 2011	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Simieneh, 2017	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Takarinda, 2012	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Tweya, 2014	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Can’t tell	Yes	No	Good
Van Rie, 2014	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Kumwenda, 2011	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Pepper, 2011	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	Yes	Good
Ndagijimana, 2015	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Njozing, 2010	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Good
Patel, 2014	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	Yes	Moderate
Hermans, 2012	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Huerga, 2010	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Kanyerere, 2012	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Ledibane, 2015	Yes	Yes	Yes	No	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Owiti, 2015	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Pathmanathan, 2018	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Ansa, 2014	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	No	Yes	Can’t tell	Yes	No	Good
Van Lettow, 2011	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	No	Yes	Can’t tell	Yes	No	Moderate
Phiri, 2011	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Can’t tell	Yes	No	Moderate

N/B: The table also includes the three studies [22, 31, 34] that quantitatively assessed factors associated with (i.e. barriers and/or enablers of) ART uptake

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ISSN: 1742-6405

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