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Table. 1 Demographic and clinical characteristics of recruited subjects

From: Advanced baseline immunosuppression is associated with elevated levels of plasma markers of fungal translocation and inflammation in long-term treated HIV-infected Tanzanians

 

Untreated (n = 40)

Virally suppressed (n = 115)

P value

Demographic data

 Median age in years (IQR)

36 (32–44)

47 (43–54)

< 0.0001a

 Gender -female n (%)

28 (70)

96 (83.5)

0.0019b

Clinical data

Median Years on treatment (IQR)

N/A

9 (7–12)

 

 Missing data

 

n = 26

 

Median current CD4 count cells/cm3 (IQR).

N/A

503 (329–633)

 

 Missing data

 

n = 7

 

Median baseline CD4 count cells/cm3 (IQR)

299 (160–486)

147 (65–217)

< 0.0001a

  Missing data

n = 5

n = 41

Current ART regimen (%)

  NNRTI based first line regimen

N/A

94(81.7)

 

  PI based second line regimen

N/A

20 (17.4)

 

 Missing data

 

1 (0.9)

 

HIV quantification

 Median Viral load copies/ml (IQR)

45,837 (7325-176350)

N/A

 

 Median proviral load copies/million PBMCs(IQR)

1422 (571–2831)

464.3 (235–758)

< 0.0001a

Serology-positive (%)

 Hepatitis C

 

2 (1.73)

 

 Epstein Barr virus

 

115 (100)

 

 Cytomegalovirus

 

107 (93.0)

 
  1. NA  not applicable, IQR interquartile range antiretroviral therapy, PBMCs peripheral blood mononuclear cells
  2. a Chi square test, b Mann–Whitney U test