From: HIV diagnosis period influences ART initiation: findings from a prospective cohort study in China
 | ALL | Diagnosed before implementing the new strategy | Diagnosed after implementing the new strategy | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
(%) | HRu | (95% CI) | P | (%) | HRu | (95% CI) | P | (%) | HRu | (95% CI) | P | |
Socio-demographic characteristics | ||||||||||||
 Age (years) | ||||||||||||
  ≤ 25 | (79.2) | 1.00 |  |  | (62.9) | 1.00 |  |  | (87.3) | 1.00 |  |  |
  25–35 | (81.4) | 1.08 | (0.83, 1.42) | 0.564 | (68.7) | 1.04 | (0.62, 1.72) | 0.896 | (89.5) | 1.28 | (0.93, 1.77) | 0.131 |
  > 35 | (88.7) | 1.30 | (0.98, 1.72) | 0.068 | (87.5) | 1.71 | (1.02, 2.87) | 0.043 | (89.4) | 1.20 | (0.86, 1.69) | 0.282 |
 Current marital status | ||||||||||||
  Single | (80.0) | 1.00 |  |  | (66.7) | 1.00 |  |  | (88.5) | 1.00 |  |  |
  Married/cohabitation | (86.4) | 1.30 | (1.02, 1.67) | 0.037 | (87.5) | 1.99 | (1.27, 3.11) | 0.003 | (85.9) | 0.99 | (0.73, 1.34) | 0.963 |
  Separated/divorced/other | (92.5) | 1.35 | (0.99, 1.84) | 0.061 | (84.2) | 1.66 | (0.96, 2.87) | 0.071 | (97.1) | 1.16 | (0.80, 1.70) | 0.436 |
 Residential district | ||||||||||||
  Urban | (86.5) | 1.00 |  |  | (76.1) | 1.00 |  |  | (92.7) | 1.00 |  |  |
  Suburb | (75.6) | 0.75 | (0.59, 0.96) | 0.020 | (65.9) | 0.72 | (0.47, 1.11) | 0.138 | (80.5) | 0.73 | (0.55, 0.97) | 0.032 |
HIV infection-related conditions | ||||||||||||
 HIV transmission mode | ||||||||||||
  Heterosexual | (79.8) | 1.00 |  |  | (82.1) | 1.00 |  |  | (78.0) | 1.00 |  |  |
  Homosexual | (85.0) | 1.14 | (0.87, 1.48) | 0.341 | (71.7) | 0.69 | (0.46, 1.05) | 0.087 | (91.6) | 1.45 | (1.03, 2.06) | 0.034 |
  Others | (75.0) | 0.89 | (0.51, 1.55) | 0.667 | (63.6) | 0.53 | (0.23, 1.2) | 0.126 | (88.9) | 2.06 | (0.96, 4.42) | 0.063 |
 Latest CD4 cell counts | ||||||||||||
  ≤ 350 | (85.8) | 1.00 |  |  | (75.9) | 1.00 |  |  | (89.0) | 1.00 |  |  |
  350–500 | (81.0) | 0.74 | (0.58, 0.94) | 0.014 | (73.3) | 0.82 | (0.53, 1.25) | 0.354 | (88.5) | 0.89 | (0.65, 1.21) | 0.448 |
  > 500 | (78.1) | 0.63 | (0.46, 0.86) | 0.003 | (69.4) | 0.69 | (0.42, 1.14) | 0.151 | (89.3) | 0.81 | (0.53, 1.23) | 0.322 |
 Self-reported health status | ||||||||||||
  Very good/good | (80.4) | 1.00 |  |  | (72.9) | 1.00 |  |  | (85.7) | 1.00 |  |  |
  Not good or poor | (84.0) | 1.13 | (0.91, 1.42) | 0.269 | (71.8) | 1.02 | (0.69, 1.50) | 0.926 | (90.1) | 1.10 | (0.84, 1.45) | 0.498 |
  Poor/very poor | (93.3) | 1.60 | (1.07, 2.41) | 0.023 | (88.9) | 1.85 | (0.88, 3.92) | 0.107 | (95.2) | 1.34 | (0.82, 2.18) | 0.240 |
 Time since diagnosis of HIV infection |  | NA |  |  |  |  |  |  |  |  |  |  |
  Within 2 years |  |  |  |  | (75.8) | 1.00 |  |  |  |  |  |  |
  More than 2 years |  |  |  |  | (71.4) | 0.96 | (0.66, 1.4) | 0.836 |  |  |  |  |
 Time since diagnosis of HIV infection |  | NA |  |  |  |  |  |  |  |  |  |  |
  Within 15 days |  |  |  |  |  |  |  |  | (91.5) | 1.00 |  |  |
  More than 15 days |  |  |  |  |  |  |  |  | (77.1) | 0.56 | (0.39, 0.79) | 0.001 |
 Time of HIV diagnosis | ||||||||||||
  Before implementing the new strategy | (73.3) | 1.00 |  |  |  | NA |  |  |  | NA |  |  |
  After implementing the new strategy | (88.9) | 2.04 | (1.62, 2.58) | < 0.001 |  |  |  |  |  |  |  |  |