Skip to main content

Table 3 Associations between ART experiences at Month 6 and mental health problems at Month 12 (among those who completed all three surveys: baseline, Month 6, and Month 12, n = 300)

From: Associations between antiretroviral therapy-related experiences and mental health status among people living with HIV in China: a prospective observational cohort study

Experiences during ART

Probable depression

Moderate/severe anxiety

ORu (95% CI)

ORaa (95% CI)

ORu (95% CI)

ORab (95% CI)

Positive experiences

 Increased CD4 cell count

1.52 (0.50, 6.57)

–

0.84 (0.27, 3.69)

–

 Improved physical health

0.42 (0.21, 0.88)*

0.63 (0.28, 1.47)

0.29 (0.13, 0.68)**

0.31 (0.12, 0.84)*

 Improved relationships with sexual partners

0.34 (0.10, 0.89)*

0.25 (0.06–0.73)*

0.28 (0.04, 0.98)†

0.17 (0.02, 0.71)*

 Regained self-confidence

0.30 (0.16, 0.60)***

0.40 (0.19–0.87)*

0.36 (0.16, 0.82)*

0.47 (0.19, 1.21)

Negative experiences

 Side effects of ART

2.16 (1.10, 4.40)*

2.07 (0.99–4.51)†

3.59 (1.48, 10.05)**

3.49 (1.35, 10.38)*

 AIDS-related symptoms

2.00 (0.92, 4.14)†

3.15 (1.30–7.57)**

2.15 (0.84, 5.09)†

2.82 (0.96, 8.04)†

 Inconvenience in daily life due to ART use

1.37 (0.63, 3.33)

–

4.04 (1.16, 25.54)†

5.74 (1.36, 41.92)*

 Exposure of HIV-positive status due to ART use

0.65 (0.25, 1.45)

–

1.29 (0.48, 3.08)

–

  1. – Not significant in univariate analysis
  2. aORa: Adjusted odds ratios, adjustment for mental health status measured at baseline (probable depression and moderate/severe anxiety) and baseline background variables with P < 0.1 (sex, monthly personal income, friend support, significant other support, and social stigma)
  3. bORa: Adjusted odds ratios, adjustment for mental health status measured at baseline (probable depression and moderate/severe anxiety) and baseline background variables with P < 0.1 (age group, sex, monthly personal income, friend support, significant other support, and social stigma)
  4. † 0.05 < P < 0.1; * P < 0.05; ** P < 0.01; *** P < 0.001