Table 5 V3 loop amino acid diversity (amino acid length, deletions, insertions, net charge) of X4 and R5 viruses in early and chronic infections
From: HIV-1 subtype C predicted co-receptor tropism in Africa: an individual sequence level meta-analysis
Country | Early X4/R5 | Chronic X4/R5 | ||||||
|---|---|---|---|---|---|---|---|---|
AA length | Deletion position | Insertion position | AA net positive charge | AA length | Deletion position | Insertion position | AA net positive charge | |
Zambia (ZM) | 34–35/35 | 24/None | None/none | 4–8/2–6 | 35/35 | None/none | None/none | 1–6/1–6 |
South Africa (ZA) | 34–35/36 | 10, 23/22 | None/9–10 | 4–8/2–6 | 34–37/34–35 | 22/22 | 7–8, 9–10, 13–14/none | 4–10/2–6 |
Tanzania (TZ) | 34–35/34–35 | 22, 24/22, 24 | None/none | 3–6/2–6 | 34–35/34–35 | 25/22, 23 | None/none | 4–6/1–6 |
Malawi (MW) | 34–35/34–35 | 24/24 | None/none | 3–5/3–5 | 34–35/34–38 | 22, 25/24 | None/13–14, 14–15 | 2–7/2–6 |
Ethiopia (ET) | 35/35 | None/none | None/none | 4–6/2–5 | 35–37/35 | None/none | 12–13/none | 3–8/0–6 |
Botswana (BW) | 35/35 | None/none | None/none | 3–6/1–6 | 34–35/34–37 | 22/22 | None/13–14 | 2–6/1–6 |