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Table 1 Demographic, clinical and virological parameters

From: Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals

Patient ID Viremic non-progressors (VNP) Typical progressors (TP) Rapid progressor (RP)
VNP-1 VNP-2 VNP-3 TP-1 TP-2 TP-3 RP
Demographics
 Agea 44 50 42 40 43 38 30
 Sexb M M M M M M M
 Race Black Caucasian Black Caucasian Black Black Black
 Risk Factorc MSM Unknown MSM MSM MSM MSM MSM
 Years HIV+d 14 17 10 14 15 12 5
 Follow up (months)e 84 37 123 35 19 31 18
CD4+ (cells/mm3)
 CD4+ countf 563 443 479 386 361 126 11
 Mean CD4+ countg 529 445 442 483 457 293 57
 Range CD4+ countg 372–711 316–608 280–814 220–789 361–645 126–511 11–124
 Slope CD4+ counth −0.6 −0.7 −0.4 −9.6 −8.2 −13.1 −4.7
HIV-1 RNA (log 10 copies/ml)
 HIV-1 RNAf 5.46 4.90 4.70 4.41 4.27 4.49 4.64
 Mean HIV-1 RNAg 4.68 4.91 4.31 4.23 4.45 4.67 4.49
 Range HIV-1 RNAg 3.61–5.45 4.27–5.08 3.62–4.71 3.89–4.62 4.28–4.62 3.90–4.90 4.09–4.66
Virus characteristics
 HIV-1 subtypei B B B B B B B
 HIV-1 coreceptor tropismj R5 R5 R5 R5 R5 R5 D/M
  1. R5 CCR5-tropic virus, D/M dual- or mixed-tropic virus
  2. a Age at the time of sampling
  3. b M male
  4. c MSM men who have sex with men
  5. d Years since first HIV-seropositive test to time of blood sample collection for this study
  6. e Number of months that the patient had been monitored up to the blood sample collection date
  7. f CD4+ T-cell count (cells/mm3) and HIV-1 RNA plasma load (log10 copies/ml) at the time the blood sample was obtained
  8. g Mean and range CD4+ T-cell count and HIV-1 RNA plasma load values determined during the clinical follow up time, to the time of blood sample collection for this study and prior to the initiation of antiretroviral treatment
  9. h Rate of CD4+ T-cell count decline (slope) calculated as cells/mm3 per month, using all CD4+ cell measurements available at the time the blood sample was obtained
  10. i HIV-1 subtype determined using the near full-length HIV-1 genome consensus sequences with the Recombinant Identification Program (RIP) from the Los Alamos HIV Sequence Database (https://www.hiv.lanl.gov/content/sequence/RIP/RIP.html) [76]
  11. j HIV-1 coreceptor tropism determined using sequencing reads corresponding to the V3 region of gp120, env gene with the DEEPGEN™HIV Software Tool Suite [70]