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Table 3 Parameter estimates for joint model of CD4 cell count change data using linear predictor

From: Joint longitudinal data analysis in detecting determinants of CD4 cell count change and adherence to highly active antiretroviral therapy at Felege Hiwot Teaching and Specialized Hospital, North-west Ethiopia (Amhara Region)

Parameter

Estimate

St. error

Adjusted rate ratio (ARR)

Wald 95% CI

p value

Intercept

4.0066

0.0029

54.9596

51.5318

58.6156

<0.0001

Age

−3.4201

0.0001

0.0327

0.0098

0.0899

0.0264*

Weight

0.0036

0.0001

1.0036

0.0021

1.0045

0.0820

Baseline CD4 cell count

0.0048

0.0002

1.0048

1.0035

1.0061

<0.0001*

Time

0.0238

0.0007

1.0240

1.0206

1.0277

<0.0001*

Marital status (ref. = without part)

 Patients living with partner

0.0064

0.0014

1.0064

0.9998

1.0132

0.0564

Sex (ref. = male)

 Female

0.0131

0.0005

1.0132

0.0124

1.0155

0.0659

Area (ref. = urban)

 Rural

−2.65

0.0005

0.0706

0.9558

1.0982

0.0525

Education (ref. = tertiary)

 No educ.

−4.02

0.0019

0.0183

0.9487

1.0298

0.0627

 Primary educ.

−3.45

0.0005

0.0317

0.9480

1.9725

0.0801

 Secondary educ.

−2.86

0.0015

0.0573

0.9337

1.0481

0.0568

Level of income (ref. = high income)

 Middle income

−4.12

0.0014

0.0162

0.9797

1.0007

0.0679

 Low income

−3.63

0.0001

0.0265

0.9816

1.0974

0.0095

Owner of cell phone (ref. = yes)

 No

−3.54

0.0018

0.0290

0.0172

0.0870

<0.0001*

First month adherence level (ref. = good adherence) 

 Fair adherence

−3.54

0.0002

0.0290

0.0097

0.0439

<0.0001*

 Poor adherence

−2.86

0.0091

0.0573

0.0214

0.0706

<0.0001*

Level of disclosed the disease (ref. = yes) 

 No

−2.6

0.0014

0.0743

0.9871

1.0995

0.0715

WHO stages (ref. = stage IV)

 Stage I

0.1191

0.0007

1.1265

0.1097

1.1436

0.0651

 Stage II

0.1239

0.0014

1.1319

0.1173

1.0461

0.0612

 Stage III

0.1006

0.0023

1.1058

0.0923

1.0196

0.0851

Time * owner of cell phone (ref. = yes) 

 Time * no

−2.96

0.0003

0.0518

0.0443

0.0996

<0.0001*

Time * area (ref. = urban) 

 Time * rural

−2.4

0.0010

0.0907

0.9937

1.0004

0.0792

Time * sex (ref. = male)

 Time * female

0.0027

0.0002

1.0027

1.0016

1.0038

<0.0001*

Time * education (ref. = tertiary)

 Time * no educ.

−4.00

0.0007

0.0183

0.0082

0.0452

<0.0001*

 Time * primary educ.

−3.83

0.0002

0.0124

0.0044

0.0360

<0.0001*

 Time * secondary educ.

−3.43

0.0001

0.0086

0.0053

0.0147

<0.0001*

Age * sex (ref. = male) 

 Age * female

−3.421

0.0002

0.0326

0.0144

0.0662

<0.0001*

Age * education (ref. = tertiary) 

 Age * no educ.

0.042

0.0002

1.0433

1.0126

1.0799

<0.0001*

 Age * primary educ.

0.032

0.0001

1.0325

1.0112

1.0601

0.0015*

 Age * secondary educ.

0.023

0.0004

1.0232

1.0093

1.0594

<0.0001*

Age * area (ref. = urban) 

 Age * rural area

0.0025

0.0002

1.0025

0.0017

1.0034

0.08621

  1. * Significant at 5% level of confidence for joint model
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AIDS Research and Therapy

ISSN: 1742-6405

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