Table 2 Type and frequency of resistance-associated mutations detected in 16 patients with virological failure
From: Early virological failure and HIV drug resistance in Ugandan adults co-infected with tuberculosis
Mutations | N (%) |
|---|---|
Any major mutation | 15 (93.8) |
Any NRTI mutation | 13 (81.2) |
Any TAM | 5 (31.3) |
3 or more TAMs | 3 (18.8) |
M41L | 2 (12.5) |
K65R | 4 (25.0) |
D67N | 2 (12.5) |
K70R | 2 (12.5) |
K70E | 1 (6.3) |
L74V/I | 1 (6.3) |
Y115F | 1 (6.3) |
M184IV | 13 (81.2) |
L210W | 1 (6.3) |
T215FY | 2 (12.5) |
K219GE | 4 (25) |
NNRTI major mutations | |
Any major mutation | 15 (93.8) |
L100I | 0 |
K101PEH | 3 (18.8) |
K103NS | 11 (68.8) |
V106AM | 1 (6.3) |
E138KAGQ | 2 (12.5) |
V179DEF | 1 (6.3) |
Y181CIV | 1 (6.3) |
Y188LCH | 1 (6.3) |
G190ASEQ | 5 (31.3) |
F227LC | 0 |
M230L | 4 (25) |
PI mutations | |
Minor | 9 (56.3) |
Major | 0 |