Table 1 Enrolment characteristics by care start cohort
Year of enrolment | 2004–05 | 2006–07 | 2008–09 | 2010–11 | 2012–13 | 2014–15 | Overall | Chi Square for trend p value |
|---|---|---|---|---|---|---|---|---|
n = 789 | n = 1435 | n = 1538 | n = 1438 | n = 1830 | n = 1600 | n = 8630 | ||
n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | ||
Gender | ||||||||
Female n (%) | 493 (62.5) | 920 (64.1) | 995 (64.7) | 914 (63.6) | 1118 (61.1) | 968 (60.5) | 5408 (62.7) | 0.0106 |
Age (in yrs.) | Â | |||||||
Mean (sd) | 38.2 (8.6)Â | 38.3 (9.0)Â | 37.6 (9.5)Â | 37.3 (9.8)Â | 37.3 (10.0)Â | 36.8 (10.7)Â | 37.5 (9.7)Â | |
Median (IQR) | 37 (32–43) | 37 (32–44) | 37 (31–43) | 36 (30–43) | 37 (30–44) | 36 29–44) | 37 (31–44) | |
Age group n (%) | ||||||||
15–19 | 3 (0.4) | 8 (0.6) | 21 (1.4) | 19 (1.3) | 44 (2.4) | 45 (2.8) | 140 (1.6) | 0.0001 |
20–24 | 14 (1.8) | 46 (3.2) | 66 (4.3) | 93 (6.5) | 118 (6.5) | 143 (8.9) | 480 (5.6) | |
25–34 | 275 (34.9) | 478 (33.3) | 528 (34.4) | 506 (35.2) | 583 (31.9) | 514 (32.1) | 2884 (33.4) | |
35–44 | 335 (42.5) | 587 (40.9) | 590 (38.3) | 505 (35.1) | 663 (36.2) | 525 (32.8) | 3205 (37.2) | |
45–54 | 121 (15.4) | 239 (16.7) | 254 (16.5) | 233 (16.2) | 328 (18) | 282 (17.6) | 1457 (16.9) | |
55+ | 41 (5.2) | 77 (5.4) | 79 (5.1) | 82 (5.7) | 94 (5.1) | 91 (5.7) | 464 (5.4) | |
Marital status n (%) | ||||||||
Single | 159 (20.2) | 281 (19.6) | 295 (19.2) | 339 (23.6) | 500 (27.3) | 477 (29.8) | 2051 (23.8) | 0.0034 |
Married | 473 (60) | 837 (58.3) | 942 (61.3) | 834 (58) | 946 (51.7) | 738 (46.1) | 4770 (55.3) | |
Divorced/separated | 38 (4.8) | 105 (7.3) | 93 (6.1) | 90 (6.3) | 169 (9.2) | 171 (10.7) | 666 (7.7) | |
Widowed | 91 (11.5) | 165 (11.5) | 152 (9.9) | 116 (8.1) | 171 (9.3) | 142 (8.9) | 837 (9.7) | |
Not documented | 28 (3.6) | 47 (3.3) | 56 (3.6) | 59 (4.1) | 44 (2.4) | 72 (4.5) | 306 (3.6) | |
Residency n (%) | ||||||||
Rural | 185 (23.5) | 257 (17.9) | 296 (19.3) | 187 (13.0) | 186 (10.2) | 62 (3.9) | 1173 (13.6) | 0.0001 |
Urban | 537 (68.1) | 1081 (75.3) | 1145 (74.5) | 1182 (82.2) | 1444 (78.9) | 1362 (85.1) | 6751 (78.2) | |
Not documented | 67 (8.5) | 97 (6.8) | 97 (6.3) | 69 (4.8) | 200 (10.9) | 176 (11.0) | 706 (8.2) | |
Patient source n (%) | ||||||||
VCT | 271 (34.4) | 588 (41) | 650 (42.3) | 628(4 3.7) | 793 (43.3) | 812(5 0.8) | 3742 (43.4) | 0.0001 |
PMTCT | 202 (25.6) | 296 (20.6) | 293 (19.1) | 232 (16.1) | 159 (8.7) | 107 (6.7) | 1289 (14.9) | |
TB clinic | 87 (11) | 189 (13.2) | 164 (10.7) | 189 (13.1) | 90 (4.9) | 1 (0.1) | 720 (8.3) | |
In-patient | 59 (7.5) | 114 (7.9) | 129 (8.4) | 98 (6.8) | 174 (9.5) | 190 (11.9) | 764 (8.9) | |
Out-patient | 9 (1.1) | 16 (1.1) | 14 (0.9) | 22 (1.5) | 63 (3.4) | 11 (0.7) | 135 (1.6) | |
Other facility | 13 (1.7) | 32 (2.2) | 29 (1.9) | 28 (2) | 169 (9.2) | 32 (2) | 303 (3.5) | |
Other source | 42 (5.3) | 67 (4.7) | 85 (5.5) | 69 (4.8) | 215 (11.8) | 416(26) | 894 (10.4) | |
Not documented | 106 (13.4) | 133 (9.3) | 174 (11.3) | 172 (12) | 167 (9.1) | 31 (1.9) | 783 (9.1) | |
HIV diagnosis n(%) | ||||||||
YoEnr ≠YoDg | 48 (6.1) | 163 (11.4) | 226 (14.7) | 247 (17.2) | 343 (18.7) | 234 (14.6) | 1261 (14.6) | 0.0412 |
YoEnr = YoDg | 345 (43.7) | 737 (51.4) | 760 (49.4) | 684 (47.6) | 787 (43.0) | 588 (36.8) | 3901 (45.2) | |
YoDg not documented | 396 (50.2) | 535 (37.3) | 552 (35.9) | 507 (35.3) | 700 (38.3) | 778 (48.6) | 3468 (40.2) | |
Clinical stage n (%) | ||||||||
Stage 1&2 | 305 (38.7) | 650 (45.3) | 890 (57.9) | 899 (62.5) | 1043 (57) | 915 (57.2) | 4702 (54.5) | 0.0001 |
Stage 3&4 | 448 (56.8) | 742 (51.7) | 608 (39.5) | 501 (34.8) | 600 (32.8) | 440 (27.5) | 3339 (38.7) | |
Not documented | 36 (4.6) | 43 (3) | 40 (2.6) | 38 (2.6) | 187 (10.2) | 245 (15.3) | 589 (6.8) | |
CD4 count | ||||||||
Median (IQR) | 178 (67–330) | 197 (80–380) | 273 (128–458) | 320 (158–507) | 279 (111–490) | 259 (101–483) | (257) (109–460) |  |
CD4 group n (%) | ||||||||
0–100 | 145 (18.4) | 303 (21.1) | 192 (12.5) | 170 (11.8) | 332 (18.1) | 290 (18.1) | 1432 (16.6) | 0.0001 |
101–200 | 86 (10.9) | 214 (14.9) | 166 (10.8) | 182 (12.7) | 232 (12.7) | 189 (11.8) | 1069 (12.4) | |
201–250 | 50 (6.3) | 67 (4.7) | 89 (5.8) | 86 (6) | 106 (5.8) | 92 (5.8) | 490 (5.7) | |
251–350 | 43 (5.5) | 142 (9.9) | 145 (9.4) | 156 (10.9) | 188 (10.3) | 148 (9.3) | 822 (9.5) | |
351–500 | 51 (6.5) | 140 (9.8) | 166 (10.8) | 216 (15) | 241 (13.2) | 168 (10.5) | 982 (11.4) | |
>500 | 47 (6) | 159 (11.1) | 194 (12.6) | 288 (20) | 341 (18.6) | 285 (17.8) | 1314 (15.2) | |
Not documented | 367 (46.5) | 410 (28.6) | 586 (38.1) | 340 (23.6) | 390 (21.3) | 428 (26.8) | 2521 (29.2) | |
Opportunistic infections n (%) | ||||||||
TB | 91 (11.5) | 178 (12.4) | 161 (10.5) | 144 (10) | 231 (12.6) | 133 (8.3) | 938 (10.9) | 0.0726 |
PCP | 33 (4.2) | 60 (4.2) | 73 (4.8) | 74 (5.2) | 89 (4.9) | 26 (1.6) | 355 (4.1) | 0.0271 |
Cryptococcal disease | 4 (0.5) | 8 (0.6) | 16 (1) | 9 (0.6) | 15 (0.8) | 9 (0.6) | 61 (0.7) | 0.7077 |
Oral candidiasis | 59 (7.5) | 106 (7.4) | 42 (2.7) | 38 (2.6) | 38 (2.1) | 35 (2.2) | 318 (3.7) | 0.0001 |
Oesophageal candidiasis | 1 (0.1) | 8 (0.6) | 6 (0.4) | 11 (0.8) | 4 (0.2) | 7 (0.4) | 37 (0.4) | 0.9132 |
Kaposi’s sarcoma | 12 (1.5) | 12 (0.8) | 20 (1.3) | 12 (0.8) | 8 (1) | 11 (0.7) | 85 (1) | 0.1126 |
Other OIa | 197 (25) | 423 (29.5) | 441 (28.7) | 502 (34.9) | 648 (35.4) | 402 (25.1) | 2613 (30.3) | 0.0162 |
Any OIb | 301 (38.2) | 601 (41.9) | 617 (40.1) | 656 (45.6) | 863 (47.2) | 519 (32.4) | 3557 (41.2) | 0.8563 |
Presenting symptoms n (%) | ||||||||
Abdominal pain | 38 (4.8) | 53 (3.7) | 55 (3.6) | 57 (4) | 76 (4.2) | 85 (5.3) | 364 (4.2) | 0.089 |
Headache | 50 (6.3) | 75 (5.2) | 97 (6.3) | 84 (5.8) | 111 (6.1) | 116 (7.3) | 533 (6.2) | 0.21 |
Cough | 167 (21.2) | 206 (14.4) | 264 (17.2) | 217 (15.1) | 315 (17.2) | 284 (17.8) | 1453 (16.8) | 0.8723 |
Chest pain | 47 (6) | 1 (2.9) | 68 (4.4) | 46 (3.2) | 65 (3.6) | 74 (4.6) | 341 (4) | 0.6866 |
Any symptom | 389 (49.3) | 643 (44.8) | 662 (43) | 526 (36.6) | 813 (44.4) | 862 (53.9) | 3895 (45.1) | 0.0369 |