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Table 2 Overview of studies in systematic review, grouped according to outcome data from virology and immunology response and serious drug- related AEs

From: Dolutegravir(DTG, S/GSK1349572) combined with other ARTs is superior to RAL- or EFV-based regimens for treatment of HIV-1 infection: a meta-analysis of randomized controlled trials

Authors and publish time

Virology and immunologic response

Serious drug- related AEs

Experiment group,  % (n/N)

Control group, n (%)

Experiment group, n (%)

Control group, n (%)

Jan van Lunzen et al. 2012. [20]

10 mg: 91 % (48/53) 25 mg: 88 % (45/51) 50 mg: 90 % (46/5150)

EFV (600 mg): 82 % (41/50)

0

2 % (1/50)

Pedro Cahn et al. 2013. [23]

50 mg: 71 % (251/354,378)

RAL (400 mg): 64 % (230/414)

1 % (2/378)

1 % (4/414)

Francois Raffi et al. 2013. [21]

50 mg: 88 % (361/411)

RAL (400 mg): 85 % (351/411)

<1 % (3/411)

1 % (5/411)

S. Walmsley et al. 2013. [22]

50 mg: 88 % (364/414)

RAL (400 mg): 81 % (338/419)

<1 % (1/414)

2 % (8/419)

  1. DTG dolutegravir, S/GSK1349572; RAL raltegravir; EFV efavirenz