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Table 1 Baseline characteristics of participants by baseline BMI, Temprano study, Abidjan, March 2008–December 2012 (N = 755)

From: High prevalence of being Overweight and Obese HIV-infected persons, before and after 24 months on early ART in the ANRS 12136 Temprano Trial

Characteristics

AD

Total N = 755 (100 %)

Underweight N = 75 (10.0 %)

Normal N = 478 (63.3 %)

Overweight N = 149 (19.7 %)

Obese N = 53 (7.0 %)

P value

Women, n (%)

755

591 (78.3)

58 (77.3)

362 (75.7)

122 (82.0)

49 (92.4)

0.02

Age (years), median (IQR)

755

35 (29–42)

35 (29–44)

35 (29–42)

35 (30–43)

40 (33–46)

0.01

Electricity, n (%)

755

720 (95.4)

68 (90.7)

453 (94.8)

147 (98.7)

52 (98)

0.006

Refrigerator, n (%)

755

314 (41.6)

25 (33.3)

186 (39)

75 (50.3)

28 (52.8)

0.01

Running water, n (%)

755

628 (83.2)

57 (76)

391 (81.8)

134 (89.9)

46 (86.8)

0.03

Marital status, n (%)

      

0.01

 Single

755

340 (45.0)

53 (33)

228 (47.7)

59 (39.6)

13 (24.5

 

 Married

755

315 (41.7)

24 (32)

193 (40.4)

69 (46.3)

29 (54.7)

 

 Divorced

755

100 (13.3)

11 (14.7)

57 (12)

21 (14)

11 (20.7)

 

Employed, n (%)

755

510 (67.6)

38 (50.7)

326 (68.2)

105 (70.5)

41 (77.4)

0.005

Smokers, n (%)

751

63 (8.4)

8 (10.6)

45 (9.5)

9 (6.1)

1 (1.9)

0.02

Alcohol use, n (%)

754

     

0.11

 Never

 

457 (60.6)

55 (73.3)

279 (58.5)

91 (61.0)

32 (60.4)

 

 Any use

 

297 (39.4)

20 (26.7)

198 (41.5)

58 (39.0)

21 (39.6)

 

 Not every day

 

290 (38.5)

19 (25.3)

192 (40.2)

58 (39.0)

21 (39.6)

 

 At least once a day

 

7 (0.9)

1 (1.4)

6 (1.3)

0 (0.0)

0 (0.0)

 

WHO stage n (%)

755

      

 1

 

483 (64.0)

36 (48)

298 (62.3)

107 (71.8)

42 (79.3)

10 −4

 2

 

190 (25.2)

27 (36)

119 (25.0)

33 (22.2)

11 (20.7)

 

 3

 

77 (10.2)

10 (13.3)

58 (12.1)

9 (6.0)

0 (0.0)

 

 4

 

5 (0.6)

2 (2.7)

3 (0.6)

0 (0.0)

0 (0.0)

 

HTN, n (%)

755

37 (4.9)

1 (1.3)

14 (2.9)

10 (6.7)

12 (22.6)

10 −4

BMI median (IQR)

755

22.3 (20–25.2)

17.6 (16.6–18.1)

21.5 (20.2–23.0)

26.5 (25.6–27.7)

31.8 (30.8–35.0)

 

Reported weight loss, n (%)

755

     

0.004

 Never

 

645 (85.4)

60 (80.0)

400 (83.7)

133 (89.3)

52 (98.0)

 

 <10 %

 

58 (7.7)

12 (16.0)

36 (7.5)

9 (6.0)

1 (2.0)

 

 >10 %

 

52 (6.9)

3 (4.0)

42 (8.8)

7 (4.7)

0 (0.0)

 

CD4 (/mm3), median (IQR)

755

442 (348–541)

446 (336–536)

439 (342–541)

440 (349–545)

481 (432–534)

0.37

CD4 count (/mm3), n (%)

       

 ≤350

 

201 (26.6)

19 (25.3)

134 (28.0)

40 (26.8)

8 (15.1)

0.62

 350–500

 

300 (39.7)

31(41.3)

187 (39.1)

59 (39.6)

23 (43.4)

 

 >500

 

254 (33.7)

25 (33.4)

157 (32.9)

50 (33.6)

22 (41.5)

 

Viral load (log), median (IQR)

754

4.7 (3.98-5.26)

4.84 (4.07–5.60)

4.72 (3.97–5.28)

4.67 (4.07–5.17)

4.44 (3.89–4.98)

0.11

Hemoglobin <95 g/dL, n (%)

754

101 (13.4)

19 (25.3)

69 (14.5)

12 (8.0)

1 (2.0)

10 −4

Hyperglycemia, n (%)

752

4 (0.5)

0 (0.0)

3 (0.6)

0 (0.0)

1 (1.9)

0.40

LDLa >4.13 mmol/L, n (%)

755

93 (12.3)

8 (10.7)

53 (11.1)

18 (12.1)

14 (26.4)

0.01

HyperTG, n (%)

754

13 (1.7)

1 (1.3)

7 (1.5)

3 (2.0)

2 (3.8)

0.26

Abdominal obesityb, n (%)

755

128 (17.0)

0 (0.0)

26 (5.4)

57 (38.2)

45 (85.0)

10 −4

Metabolic syndromec, n (%)

755

47 (6.2)

0 (0)

11 (23.4)

16 (34)

20 (42.6) 

10 −4

  1. Italic values are statistically significant
  2. AD available data, N, n Number, % percentage, IQR interquartile range, P value comparisons are made using the chi square or fisher test to compare proportions or then the Wilcoxon test for median comparison, BMI body mass index, underweight BMI <18.5 kg/m2, Normal BMI 18.5–24.9 kg/m2, Overweight BMI 25–29.9 kg/m2, Obese BMI >30 kg/m2, Smokers report smoking regularly and at least one pack of cigarettes daily, Employed report holding a job in the public, private, or informal sector, SBP systolic blood pressure, DBP diastolic blood pressure, HTN arterial hypertension (SBP ≥140 mmHg and DBP ≥90 mmHg), HyperTG hypertriglyceridemia (>2.3 mmol/L), Hyperglycemia blood glucose ≥7 mmol/L
  3. a LDL estimated with Friedwald formula: (Total Cholesterol)—(HDL Cholesterol)—(TG/5)
  4. b Abdominal obesity (>101 cm for men; >87 cm for women)
  5. c Metabolic syndrome: At least three of the five following criteria: hyperglycemia (≥7 mmol/L); low HDL (<1 mmol/L in men or <1.3 mmol/L in women); hypertriglyceridemia (>1.7 mmol/L); abdominal obesity (>101 cm for men; >87 cm for women) and HTN (SBP >140 mmHg or DBP >90 mmHg)
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AIDS Research and Therapy

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