Table 1 Characteristics of the patients and clinical data depending on HAART use during ICU stay*
Characteristics and clinical data | Total (n = 91) | without HAART (n = 59) | with HAART (n = 32) | p |
|---|---|---|---|---|
Characteristics | ||||
Age (in years) | 42 ± 10 | 42 ± 9 | 43 ± 11 | 0.98 |
Sex (M/F) | 61/30 | 40/19 | 21/11 | 0.99 |
SAPS II on admission | 47 ± 20 | 48 ± 21 | 46 ± 17 | 0.83 |
Glasgow score | 12 ± 4 | 12 ± 5 | 13 ± 4 | 0.24 |
Main reasons for ICU admission | ||||
Respiratory | 46 (51) | 28 (47) | 18 (56) | 0.51 |
Neurologic | 25 (27) | 16 (27) | 9 (28) | 0.99 |
Shock | 10 (11) | 6 (10) | 4 (13) | 0.99 |
Others | 10 (11) | 9 (15) | 1 (3) | 0.09 |
HIV infection | ||||
Initial HIV diagnosis | 17 (19) | 16 (27) | 1 (3) | 0.004 |
Stage C | 69 (76) | 43 (73) | 26 (81) | 0.85 |
CD4 count at admission (cells/mm3) | 112 [1–935] | 100 [2–935] | 161 [1–822] | 0.68 |
Viral load at admission (log10) | 3.38 ± 1.60 | 3.86 ± 1.51 | 2.63 ± 1.45 | 0.0005 |
AIDS related diagnosis at ICU admission | 46 (51) | 33 (56) | 13 (41) | 0.25 |
Opportunistic infections | ||||
Pneumocystis jirovecii | 12 | 10 | 2 | 0.2 |
Toxoplasmosis | 7 | 5 | 2 | 0.99 |
Mycobacterial infections | 7 | 4 | 3 | 0.69 |
Pneumonia | 3 | 2 | 1 | 0.99 |
Others | 5 | 3 | 2 | 0.99 |
Care in ICU | ||||
Mechanical ventilation (MV) | 45 (49) | 29 (49) | 16 (32) | 0.87 |
Duration of ventilation (days) | 5 ± 10 | 5 ± 11 | 5 ± 9 | 0.81 |
Renal replacement | 7 (8) | 3 (5) | 4 (13) | 0.33 |
Vasoactive drugs | 22 (24) | 15 (25) | 7 (22) | 0.99 |
Duration of vasoactive drugs (days) | 1 ± 2 | 1 ± 2 | 1 ± 2 | 0.99 |
ICU length of stay (days) | 8 ± 10 | 8 ± 11 | 8 ± 9 | 0.43 |
Death in ICU | 17 (19) | 12 (20) | 5 (16) | 0.78 |