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Table 2 HIV-1 co-receptor usage and its associated influence factors

From: Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic

 

R5 co-receptor usage

X4 co-receptor usage

  

CD4 + T count (cells/mm 3 )

    

 CD4 < 200

18 (66.7%)

9 (33.3%)

p = 0.26

 

 200 = CD4 < 350

15 (93.8%)

19 (6.2%)

  

 350 = CD4 < 500

11 (73.3%)

4 (26.7%)

  

 CD4 > =500

5 (55.6%)

4 (44.4%)

  

Gender

    

 Female

32 (72.7%)

12 (27.3%)

p = 0.97

 

 Male

17 (73.9%)

6 (26.1%)

  

Age

    

 16-25 years

2 (50.0%)

2 (50.0%)

p = 0.22

 

 26-35 years

15 (83.3%)

3 (16.7%)

  

 36-45 years

20 (66.7%)

10 (33.3%)

  

 > 46 years

12 (80.0%)

3 (20.0%)

  

Therapeutic regimen

    

 AZT/d4T + 3TC + NVP/EFV

13 (59.1%)

9 (40.9%)

p = 0.31

 

 TDF/ABC + 3TC + DDI/LPV/r*

19 (79.2%)

5 (20.8%)

  

 Treatment Naïve

17 (81%)

4 (19%)

  

HIV-1 Subtype

    

 A

36 (78.3%)

10 (21.7%)

p = 0.261

p = 0.04

 C

9 (81.8%)

2 (18.2%)

p = 0.504

 

 D

4 (40%)

6 (60%)

p = 0.015