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Table 2 Summary of the ARV Class Combinations Comprising the Salvage ARV Regimens

From: Standardized representation, visualization and searchable repository of antiretroviral treatment-change episodes

Type 1 Regimens NRTIs, NNRTIs, and/or PIs Type 2 Regimens Raltegravir (RAL), enfuvirtide (ENF), and/or Maraviroc (MVC)
ARV Class Combination No. TCE ARV Class Combination No. TCE
2 NRTIs + PI/r 364 ≥1NRTI + PI/r + RAL 37
≥3 NRTIs + PI/r 194 ≥1NRTI + PI/r + ENF 30
2 NRTIs + NNRTI 149 ≥1NRTI + NNRTI + PI/r + RAL 13
1 NRTI + NNRTI + PI/r 102 ≥1NRTI + NNRTI + PI/r + ENF 7
2 NRTIs + NNRTI + PI/r 90 ≥1NRTI + RAL 7
2 NRTIs + PI 90 ≥1NRTI + PI/r + RAL + ENF 6
≥3 NRTIs + NNRTI 79 PI/r + RAL 5
≥3 NRTIs 62 PI/r + RAL + MVC 5
1 NRTI + NNRTI + PI 49 ≥1NRTI + NNRTI + RAL 4
1 NRTI + PI/r 45 ≥1NRTI + PI/r + RAL + MVC 4
2 NRTIs + NNRTI + PI 44 ≥1NRTI + RAL + MVC 4
≥3 NRTIs + PI 36 NNRTI + PI/r + RAL 3
≥3 NRTIs + NNRTI + PI/r 25 ≥1NRTI + NNRTI + PI + ENF 2
NNRTI + PI 19 ≥1NRTI + NNRTI + RAL + ENF 2
≥3 NRTIs + NNRTI + PI 9 ≥1NRTI + PI/r + MVC 2
PI/r 3 ≥1NRTI + PI/r + MVC + ENF 2
   NNRTI + RAL + MVC 2
Miscellaneous 22 Miscellaneous 10
Total 1,382 Total 145
  1. Fewer than 10 individuals received a double-boosted PI either as part of a Type 1 or Type 2 Regimen. The PI component in these individuals was denoted here as PI/r.
  2. To avoid subdividing the Type 2 Regimens into too many small categories, no distinction was made based on the number of NRTIs in the regimen.
  3. Abbreviations: NRTIs nucleoside RT inhibitors, NNRTIs non-nucleoside RT inhibitors, PIs protease inhibitors, PI/r ritonavir-boosted PIs.