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Table 5 Determinants of abnormal lipid profile in 138 first-line ART treated individuals in Yaounde, Cameroon

From: First-line antiretroviral therapy and dyslipidemia in people living with HIV-1 in Cameroon: a cross-sectional study

Outcome variables Explanatory variables OR pa Ajusted OR pb
   (95%CI)   (95% CI)  
TC ≥ 200 (mg/dl) Sex (Women vs. Men) 0.99 (0.48-2.04) 0.99 0.96 (0.45-2.03) 0.93
  Age > 40 years 1.38 (0.69-2.76) 0.36 1.41 (0.69-2.91) 0.35
  BMI > 25 kg/m2 1.22 (0.59-2.52) 0.59 1.06 (0.49-2.29) 0.88
  Treatment duration > 2 years 2.07 (1.03-4.17) 0.04 2.08 (1.01-4.27) 0.05
  d4T vs. AZT regimen 0.75 (0.36-1.56) 0.44 0.78 (0.32-1.81) 0.55
  NVP vs. EFV regimen 0.79 (0.26-2.41) 0.67 0.79 (0.21-2.99) 0.73
  Past history of tuberculosis 0.80 (0.39-1.62) 0.54 0.85 (0.41-1.80) 0.68
LDL-c ≥ 130 (md/dl) Sex (Women vs. Men) 0.70 (0.33-1,51) 0.32 0.67 (0.32-1.40) 0.29
  Age > 40 years 0.74 (0.36-1.54) 0.38 0.57 (0.28-1.18) 0.23
  BMI > 25 kg/m2 2.23 (1.04-4.80) 0.02 2.65 (1.24-5.68) 0.01
  Treatment duration > 2 years 0.93 (0.45-1.93) 0.83 0.87 (0.42-1.80) 0.71
  d4T vs. AZT regimen 1.73 (0.79-3.78) 0.13 1.71 (0.72-4.06) 0.22
  NVP vs. EFV regimen 1.18 (0.34-4.01) 0.77 0.99 (0.26-3.72) 0.98
  Past history of tuberculosis 1.54 (0.73-3.25) 0.22 1.72 (0.89-3.62) 0.15
TC/HDL-c ratio ≥ 5 Sex (Women vs. Men) 1.79 (0.79-4.14) 0.13 1.61 (0.73-3.54) 0.23
  Age > 40 years 0.67 (0.31-1.43) 0.26 0.72 (0.34-1.50) 0.38
  BMI > 25 kg/m2 0.99 (0.45-2.16) 0.97 0.88 (0.41-1.89) 0.74
  Treatment duration > 2 years 1.93 (0.60-2.97) 0.08 1.90 (0.89-4.06) 0.1
  d4T vs. AZT regimen 1.33 (0.60-2.97) 0.44 1.56 (0.66-3.73) 0.31
  NVP vs. EFV regimen 1.01 (0.27-3.58) 1 0.68 (0.17-2.65) 0.58
  Past history of tuberculosis 0.72 (0.34-1.56) 0.37 0.77 (0.37-1.63) 0.5
  1. BMI, body mass index; OR, odds ratio; CI, confidence interval; LDL-c, LDL cholesterol; TC, total cholesterol; HDL-c, HDL cholesterol; pa, p value for unadjusted odds ratio; pb, p value for adjusted odds ratio