Table 1 Patients' characteristics at inclusion (n = 514).
Groups | A n = 50 | B n = 80 | C n = 81 | D n = 303 |
|---|---|---|---|---|
Age, years | 39 (20 - 51) | 41 (32 - 66) | 41 (25 - 75) | 41 (23 - 75) |
Male | 42 (84%) | 62 (77.5%) | 50 (61.7%) | 223 (73.6%) |
Weight, kg | 68 (50 - 102) | 64 (42 - 98.5) | 65.5 (36 - 111) | 65.9 (39 - 121) |
Risk factor for HIV | ||||
IV drug use | 23 (46%) | 64 (80%) | 53 (65.4%) | 185 (61.1%) |
Hetero/homosexual | 27 (64%) | 15 (20%) | 26 (32.1%) | 110 (36.3%) |
Blood products transfusion | 1 (1.2%) | 3 (1%) | ||
Unknown | 1 (1.2%) | 5 (1.7%) | ||
Methadone treatment | 11 (22%) | 36 (45%) | 20 (24.7%) | 56 (18.5%) |
Active illegal drug use | 4 (8%) | 14 (17.5%) | 8 (9.9%) | 17 (5.6%) |
CD4/μl | 140 (4 - 563) | 227 (4 - 546) | 277 (14 - 923) | 475 (27 - 1196) |
HIV-RNA log10 cop./ml | 5.16 (2.0-6.36) | 4.61 (2.05-6.54) | 3.52 (2.04-4.64) | < 1.69 (< 1.69-2.45) |
Clinical category C | 10 (20%) | 26 (32.6%) | 28 (34.6%) | 98 (32.4%) |
Nadir CD4/μl | 152 (4 - 417) | 120 (1 - 476) | 120 (1 - 815) | 130 (1 - 825) |
Previous ART (months) | - | 46 (1 - 164) | 38 (1 -192) | 71 (1 - 269) |
Associated NRTIs | ||||
TDF + FTC | 34 (68%) | 46 (57.5%) | 28 (34.6%) | 110 (36.3%) |
ABV + 3TC | 8 (16%) | 15 (18.8%) | 14 (17.3%) | 78 (25.7%) |
ddI + 3TC | 5 (10%) | 3 (3.8%) | 5 (6.2%) | 37 (12.2%) |
Others | 3 (6%) | 16 (20.8%) | 34 (41.9%) | 78 (25.7%) |
Chronic viral hepatitis | 22 (44%) | 63 (78.8%) | 48 (59.3%) | 190 (62.7%) |
HCV | 21 (42%) | 55 (68.8%) | 45 (55.5%) | 185 (61.0%) |
HBV | 1 (2%) | 2 (2.5%) | 2 (2.5%) | 2 (0.7%) |
HCV + HVB | - | 2 (2.5%) | 1 (1.2%) | 3 (1.0%) |
Cirrhosis | 4 (8%) | 4 (5%) | 6 (7.4%) | 26 (8.6%) |