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Table 3 Laboratory values of patients with and without immune restoration disease before and after HAART commencement, at Zewditu Memorial Hospital, Addis Ababa, Ethiopia

From: Immune restoration disease and changes in CD4+ T-cell count in HIV- infected patients during highly active antiretroviral therapy at Zewditu memorial hospital, Addis Ababa, Ethiopia

Variables Patients with IRD (n = 170) Patients without IRD (n = 996)
  Mean (SD) values at baseline Mean (SD) values after 6 months P-value Mean (SD) values at baseline Mean (SD) values after 6 months P-value
CD4+ (cells/μl) 84 (57.8)* 185(94.8) 0.001 116 (69.4) 236(120) 0.001
WBC (cells/μl) 4246(1948) 5725 (3124) 0.001 4814 (1729) 6516(2072) 0.001
Hgb (gm/dl) 11.5(2.9) 12.1 (4.7) 0.400 12.2 (2.7) 13.9 (3.8) 0.001
AST (IU/L) 30.7(23.2) 37.8(28.8) 0.020 30(25.7) 43 (34.2) 0.001
ALT (IU/L) 25.3(20.2) 33.4(28.9) 0.003 25.1(23) 39 .2(34) 0.001
ALP (IU/L) 208(160) 213(167) 0.770 190 (149.9) 251 (212) 0.001
  1. * Mean (SD); IRD, immune restoration disease; WBC, white blood cell; Hgb, hemoglobin; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase.