Skip to main content

Table 2 Pooled-analysis of one-year HIV-related mortality rates for HIV patients initiating HAART at CD4 counts <50, 50-199 and 200-350 cells/μl.

From: Further benefits by early start of HIV treatment in low income countries: Survival estimates of early versus deferred antiretroviral therapy

Study

n

Median age

Weight (%)

Absolute risk of death per year (95% CI)

Baseline CD4 count <50

    

   Year 1 on HAART

    

ART LINC (12)

1474

36

0.18

0,062 (0,049 - 0,074)

Senegal (24)

96

37

0.01

0,179 (0,115 - 0,272)

South Africa (30)

155

31

0.02

0,182 (0,13 - 0,253)

Cambodia (ref)

416

33.6

0.05

0,130 (0,100 - 0,170)

Botswana 2 (Wester)

43

36

0.01

0,240 (0,116 - 0,355)

Côte d'Ivoire (23)

2655

36

0.33

0,230 (0,200 - 0,250)

Botswana 1 (Mujugira)

349

35

0.04

0,340 (0,288 - 0,388)

Zambia (29)

2797

35

0.35

0,308 (0,291 - 0,325)

Weighted mean (weighted CI)

7985

  

0,224 (0,215 - 0,233)

   Year 2+ on HAART

    

Senegal (24)

79

37

1.00

0,088 (0,026 - 0,150)

Weighted mean (weighted CI)

79

  

0,088 (0,026 - 0,150)

Baseline CD4 count 50-199

    

   Year 1 on HAART

    

ART LINC (12)

2022

36

0.10

0,030 (0,022 - 0,037)

West-Africa (25)

232

34

0.01

0,050 (0,026 - 0,087)

Senegal (27)

176

38

0.01

0,074 (0,052 - 0,105)

Botswana 2 (Wester)

87

36

0.00

0,097 (0,035 - 0,156)

Haiti (28)

1004

NA

0.05

0,140 (0,117 - 0,162)

Senegal (24)

177

37

0.01

0,131 (0,089 - 0,190)

South Africa (30)

132

31

0.01

0,086 (0,049 - 0,151)

South Africa (39)

81

NA

0.00

0,069 (0,031 - 0,133)

Côte d'Ivoire (23)

7556

36

0.39

0,090 (0,070 - 0,110)

Zambia (29)

6787

35

0.35

0,140 (0,132 - 0,148)

Malawi (ref)

1298

34.9

0.07

0,190 (0,170 - 0,190)

Weighted mean (weighted CI)

19552

  

0,110 (0,106 - 0,114)

   Year 2+ on HAART

    

Malawi (ref)

1051

34.9

0.87

0,09 (0,070 - 0,110)

Senegal (24)

154

37

0.13

0,06 (0,025 - 0,095)

Weighted mean (weighted CI)

1205

  

0,088 (0,072 - 0,104)

Baseline CD4 count 200-350

    

   Year 1 on HAART

    

ART LINC (12)

940

36

0.23

0,011 (0,004 - 0,017)

West-Africa (25)

408

34

0.10

0,017 (0,006 - 0,038)

Senegal (24)

122

37

0.03

0,058 (0,028 - 0,119)

South Africa (39)

110

NA

0.03

0,014 (0,002 - 0,049)

Zambia (29)

2506

35

0.61

0,094 (0,083 - 0,105)

Weighted mean (weighted CI)

4086

  

0,064 (0,057 - 0,071)

   Year 2+ on HAART

    

Senegal (24)

115

37

1.00

0,024 (-0,004 - 0,052)

Weighted mean (weighted CI)

115

  

0,024 (-0,004 - 0,052)

  1. NA = Not Available
Back to article page

AIDS Research and Therapy

ISSN: 1742-6405

Contact us