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Table 2 Potential predictors associated with virological treatment failure (>400 HIV RNA cop/ml) after 6 months of initiating ART

From: Antiretroviral treatment adherence and its determinants in Sub-Saharan Africa: a prospective study at Yaounde Central Hospital, Cameroon

  Self reported adherence CD4 count change Pharmacy refill history
  100% <100% Immunological success Immunological failure Regular, continuous Irregular or interrupted
Total (Nb) 140 25 51 14 147 47
Virological success (Nb) 125 22 44 6 140 29
Virological failure (Nb) 15 3 7 8 7 18
OR (95%CI) 1.13 (0.30-4.25) 7.78 (1.68-36.0) 12.4 (4.75-32.4)
Sensitivity 0.17 0.53 0.72
Specificity 0.85 0.88 0.83
Positive predictive value 0.12 0.57 0.38
Negative predictive value 0.83 0.86 0.95
Positive likelihood ratio 1.13 1.23 4.23
Negative likelihood ratio 0.97 0.53 0.34
  1. Viral load measurement was available for 206 patients. Immunological success means a rise above 100 cells/μl; immunological failure means a drop to pre-treatment levels or <100 cells/μl,)