Table 1 FDA approved assays for the quantification of HIV RNA
From: HIV-2 diagnosis and quantification in high-risk patients
Assay | Manufacturer | Technique | Sensitivity (copies/ml) | HIV-1 Subtypes | HIV-2 |
|---|---|---|---|---|---|
Roche | RT-PCR | 50†-750,000 | Group M (subtypes A-H) | Detected 3/4 HIV-2 [37] | |
Versant HIV-1 RNA 3.0 [41] | Bayer | bDNA | 75–500,000 | Group M (subtypes A-G) | No [42] |
BioMereiux | NASBA | 176–3.4 million | Group M (not subtype G) | YES [36] (subtype A) | |
COBAS AmpliPrep, Taqman HIV-1 [44] | Roche | RT-PCR | 48–10 million | Group M (subtypes A-H) | |
RealTime HIV-1 [45] | Abbott | RT-PCR | 40–10 million | Group M, N, O, recombinants | No [45] |