Assessing the effect of HAART on change in quality of life among HIV-infected women

Liu, Chenglong; Weber, Kathleen; Robison, Esther; Hu, Zheng; Jacobson, Lisa P; Gange, Stephen J

doi:10.1186/1742-6405-3-6

AIDS Research and Therapy

Table 3 Estimates of the Impact of HAART on the Mean Change in QOL Scores from Propensity-Score Matched Pattern Mixture Models among AIDS-free Women at Matching Visits

From: Assessing the effect of HAART on change in quality of life among HIV-infected women

		Model 1^a		Model 2^b		Model 3^c		Model 4^d		Model 5^e
		Effect	P-Value	Effect	P-Value	Effect	P-Value	Effect	P-Value	Effect	P-Value
Overall QOL	Short-Term HAART Effect	0.57	0.70	0.40	0.79	0.43	0.78	0.63	0.69	1.61	0.35
	Change per 6 months	-0.24	0.10	-0.26	0.08	-0.19	0.23	-0.26	0.11	-0.20	0.16
Physical functioning	Short-Term HAART Effect	0.05	0.98	-0.19	0.94	-0.23	0.92	-0.88	0.73	0.55	0.83
	Change per 6 months	-0.27	0.25	-0.28	0.23	-0.26	0.31	-0.37	0.14	-0.25	0.26
Role functioning	Short-Term HAART Effect	2.48	0.33	2.61	0.30	2.73	0.28	3.03	0.24	4.13	0.12
	Change per 6 months	-0.30	0.25	-0.26	0.32	-0.28	0.33	-0.33	0.26	-0.26	0.35
Energy/fatigue	Short-Term HAART Effect	-2.22	0.30	-2.12	0.31	-2.14	0.31	-1.67	0.44	-0.71	0.75
	Change per 6 months	-0.25	0.22	-0.30	0.16	-0.19	0.42	-0.26	0.27	-0.24	0.28
Social functioning	Short-Term HAART Effect	3.17	0.12	3.71	0.08	3.85	0.08	4.33	0.05	5.27	0.02
	Change per 6 months	-0.17	0.43	-0.16	0.44	-0.08	0.73	-0.09	0.71	0.01	0.97
Cognitive functioning	Short-Term HAART Effect	0.86	0.61	2.21	0.22	2.23	0.22	2.54	0.16	2.38	0.22
	Change per 6 months	-0.13	0.46	-0.11	0.52	-0.05	0.79	-0.06	0.76	-0.11	0.54
Pain	Short-Term HAART Effect	3.25	0.13	2.53	0.24	2.69	0.21	3.46	0.13	5.96	0.02
	Change per 6 months	-0.21	0.36	-0.26	0.28	-0.11	0.67	-0.17	0.52	-0.11	0.66
Emotional well-being	Short-Term HAART Effect	1.56	0.40	1.06	0.58	1.06	0.58	1.02	0.58	0.17	0.93
	Change per 6 months	-0.19	0.32	-0.18	0.34	-0.16	0.42	-0.20	0.36	-0.23	0.26
Health perception	Short-Term HAART Effect	0.07	0.97	0.36	0.84	0.27	0.88	0.31	0.87	0.45	0.82
	Change per 6 months	-0.36	0.04	-0.37	0.04	-0.37	0.06	-0.50	0.01	-0.54	0.00
Perceived health index	Short-Term HAART Effect	3.17	0.07	3.76	0.03	3.46	0.05	4.03	0.02	4.08	0.03
	Change per 6 months	-0.21	0.21	-0.20	0.22	-0.28	0.11	-0.31	0.08	-0.26	0.14

^aModel 1: Model includes an intercept, an indicator of HAART or HAART-naïve group (Short-Term HAART Effect) and the time from index visit (Change per 6 months).
^bModel 2: Model 1 + age, ethnicity and education level.
^cModel 3: Model 2 + income, employment and health insurance.
^dModel 4: Model 3+ CD4+ cell counts and viral load.
^eModel 5: Model 4+ number of symptoms, outpatient visits, hospitalizations and medication, AIDS history and clinical depression. Interactions between HAART and time from index visit were not statistically significant for all models.

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ISSN: 1742-6405

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