Table 1 Patient characteristics
Age (y) | Gender | Ethnicity | Duration of diagnosed HIV (mo) | ART duration (mo) | Nadir CD4 count (cells/uL) | Current CD4 count (cells/uL) | LDS | ART (current) | ART (lifetime) | COX defect (%) | Serum FGF-21 (pg/mL) |
|---|---|---|---|---|---|---|---|---|---|---|---|
71 | M | WB | 130 | 130 | UK | 530 | Y | TDF FTC EFV | ddi AZT 3TC EFV TDF FTC | 3.0% | 232 |
48 | F | BA | 100 | 99 | 10 | 487 | N | TDF FTC NVP | AZT 3TC EFVTDF FTC NVP | 0.1% | >1920 |
34 | F | WB | 88 | 86 | 218 | 1121 | Y | ABC 3TC NVP | AZT 3TC NVP ABC | 0.0% | 560 |
55 | F | BA | 64 | 27 | 112 | 426 | N | TDF FTC AZT DRV/r | TDF FTC LPV/r AZT DRV/r | 0.8% | 164 |
43 | M | BA | 87 | 87 | 152 | 306 | N | TDF FTC EFV | AZT 3TC EFV TDF FTC | 0.8% | 20 |
42 | M | WB | 185 | 147 | 150 | 636 | N | AZT 3TC EFV | AZT 3TC NVP | 0.0% | 342 |
63 | M | WB | 97 | 97 | 169 | 870 | N | ABC 3TC EFV | AZT 3TC EFV ABC | 0.0% | 204 |
29 | M | WB | 84 | 32 | 197 | 401 | N | TDF FTC EFV | TDF FTC EFV | 0.0% | 809 |
63 | M | WB | 238 | 221 | NA | 438 | N | ABC 3TC NVP | AZT ddl d4T 3TC ddC IDV NVP ABC | 2.2% | 440 |
62 | M | WB | 63 | 62 | 56 | 190 | N | TDF FTC NVP | TOP FTC NVP | 0.2% | 156 |
52 | M | WB | 225 | 225 | 120 | 728 | Y | TDF FTC ATV/r | AZT ddC ddl 3TC d4T SQV NVP IDV NFV ABC TDF LPV/r FTC ATV/r | 1.3% | 328 |
36 | M | WB | 139 | 138 | 197 | 627 | N | AZT 3TC EFV | AZT 3TC EFV TDF FTC | 0.3% | 214 |
51 | M | WB | 190 | 183 | 10 | 747 | N | ABC TDF NVP | AZT ddl d4T 3TC RTV NVP IDV ddC ABC ATV/r TDF | 4.9% | 252 |
33 | F | WB | 96 | 95 | 83 | 1289 | N | TDF FTC EFV | AZT 3TC EFV TDF FTC | 0.0% | 177 |
48 | M | WB | 102 | 100 | 259 | 1329 | Y | AZT 3TC EFV | AZT 3TC EFV | 0.4% | 409 |
51 | M | WB | 145 | 144 | 151 | 421 | N | AZT 3TC NVP | AZT 3TC NVP | 1.4% | 254 |
66 | M | WB | 71 | 26 | 287 | 455 | N | TDF FTC EFV | TDF FTC EFV | 11.2% | 470 |
46 | M | WB | 158 | 157 | 250 | 1452 | N | TDF FTC EFV | AZT 3TC IDV EFV ABC TDF FTC | 1.4% | 1218 |
61 | M | WB | 116 | 113 | NA | 498 | Y | TDF FTC NVP | AZT 3TC EFV NVP TDF FTC | 2.4% | 182- |
30 | M | WB | 88 | 23 | 283 | 661 | N | TDF FTC DRV/r | TDF FTC EFV DRV/r | 0.1% | 207 |
62 | M | WB | 284 | 202 | NA | 422 | N | ABC NVP LPV/r | SQV AZT ddC 3TC d4T ddl IDV ABC NVP NFV LPV/r | 0.8% | 92 |
45 | WB | 159 | 158 | 176 | 660 | N | TDF FTC NVP | AZT 3TC IDV NVP TDF FTC | 0.0% | 60 | |
54 | M | WB | 79 | 38 | 244 | 638 | N | TDF FTC DRV/r | TDF FTC EFV DRV/r | 3.4% | 178 |
52 | M | WB | 166 | 164 | 0 | 662 | Y | TDF FTC NVP | AZT d4T IDV NFV SQV 3TC NVP ddl TDF FTC | 2.8% | 525 |
51 | M | WB | 243 | 171 | 327 | 539 | Y | TDF FTC EFV | AZT ddl RTV NFV TDF FTC EFV | 1.5% | 231 |
35 | F | BA | 62 | 25 | 380 | 638 | N | TDF FTC EFV | TOP FTC EFV | 0.0% | 82 |
53 | M | WB | NA | 48 | 301 | 804 | N | TDF FTC EFV | TDF FTC EFV | NA | 490 |
36 | M | WB | 130 | 130 | 18 | 898 | N | TDF FTC ATV/r | AZT 3TC EFV TDF FTC ATV/r | 0.0% | 530 |
48 | M | WB | 53 | 14 | 332 | 443 | N | TDF FTC EFV | TDF FTC EFV | 0.0% | 56 |
52 | F | BA | 83 | 81 | 17 | 485 | Y | TDF FTC EFV | AZT 3TC EFV TDF FTC | 0.7% | 224 |
38 | M | WB | 129 | 128 | 4 | 761 | Y | TDF FTC EFV | AZT 3TC EFV TDF FTC | 0.0% | 935 |
47 | M | WB | 183 | 164 | 305 | 668 | Y | ABC RAL ATV/r | d4T 3TC NVP ddl IDV ABC ATV/r RAL | 9.8% | 114 |