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Table 1 Baseline characteristics of the study populations (n = 232)

From: Virologic and immunologic outcome of HAART in Human Immunodeficiency Virus (HIV)-1 infected patients with and without tuberculosis (TB) and latent TB infection (LTBI) in Addis Ababa, Ethiopia

 

HIV + TB+

HIV + TB-

HIV-TB+

HIV-TST+

HIV-TST

(n = 59)

(n = 125)

(n = 13)

(n = 10)

(n = 25)

Demographic data

     

Age, years

33.1 ± 8.7

33.2 ± 7.3

28.5 ± 9.5 b

26.6 ± 7.4,

24.6 ± 6.6

Female, n (%)

28 (47.5)

83 (66.4)

6 (46.2)

6 (60)

16 (64)

Clinical data

     

CHBV coinfection, n (%)

11/57 (19.3)

8/112 (7.2)

3 (15)

2 (20)

1 (4)

WHO stage, n (%)

     

  I + II

3/50 (6)

80 (64)

   

  III + IV

47/50 (94)

45 (36)

NA

NA

NA

BMI, kg/m2

18.9 ± 3.1a

21.3 ± 3.5

18.9 ± 2.8

21.4 ± 2.5

21.4 ± 2.0

BMI < 18.50 kg/m2, n (%)

29 (49.2)

18/124 (14.6)

6 (46)

8 (80)

24 (96)

Laboratory data

     

Hgb, g/dl

12.2 ± 3.7 a

13.2 ± 2.5

13.5 ± 2.5 b

16.4 ±1.8 c

18.0 ± 2.1

Hgb < 12 g/dl (anemic), n (%)

23/43 (53.5)

29/107 (27.1)

2 (23)

0

0

CD4+ count/μl

173.7 ± 180.8 a

279.2 ± 212.4

478.1 ± 253 b

787.3 ± 274

754.8 ± 241

CD4+ category, n (%)

     

  < 100

27 (48.2)

26 (22.2)

1 (1.7)

0

0

  100 –200

12 (21.4)

26 (22.2)

6 (10.0)

0

0

  > = 201

17 (30.3)

65 (55.6)

53 (88.3)

10 (100)

25 (100)

TLC

1175 ± 754 a

1626 ± 750

1485 ± 895 b

1975 ± 1483

1.668 ± 559

HIV RNA (log10copies/ml)

4.5 ± 0.8 a

4.1 ± 0.9

NA

NA

NA

HIV RNA category, n (%)

     

  LDL

1 (2.2)

9 (8.0)

   

  <= 100000

14 (30.4)

97 (85.8)

   

  >100000

32 (69.6)

16 (14.2)

NA

NA

NA

  1. Data are means ± standard deviations (SD) unless stated; n (%) Number of patients, CHBV chronic Hepatitis B Virus, defined as the presence of hepatitis surface antigen (HBsAg) in the plasma, BMI Body mass index, Hgb Hemoglobin, TLC total lymphocyte, HIV RNA plasma viral load, LDL lower than detection limit (HIV RNA < 50 copies/ml), WHO World Health Organization, NA: not applicable.
  2. a Comparing HIV + TB + and HIV + TB-; P < 0.05.
  3. b Comparing HIV + TB + and HIV-TB+; P < 0.05.
  4. c Comparing HIV-TST + and HIV-TST- ; P < 0.05.