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Figure 2 | AIDS Research and Therapy

Figure 2

From: Mutations in variable domains of the HIV-1 envelope gene can have a significant impact on maraviroc and vicriviroc resistance

Figure 2

Effect of Env glycoprotein mutations on infectivity of the HIV-1 strain CC1/85. U87-CD4-CCR5 cells were infected with HIV-1 Env pseudoviruses bearing parental clone (wild type) or Env single mutants V169M, L317W, I408T, double mutants V169M/L317W, V169M/I408T, L317W/I408T and the triple mutant V169M/L317W/I408T. Means from 3 independent experiments performed in triplicate are reported. Pseudovirus infectivity was calculated as RLU of the mutant/RLU of the wild type × 100%.

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AIDS Research and Therapy

ISSN: 1742-6405

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