Table 1 Clinical and laboratory characteristics of ALHIV on DTG by current BMI in Kampala, Uganda

Sex

0.001

Female

68 (44.4)

12 (100)

80 (48.5)

Male

85 (56.6)

0

85 (51.5)

Age (years)

0.357

10–14

88 (57.5)

8 (66.7)

96 (58.2)

15–17

45 (29.4)

4 (33.3)

49 (29.7)

18–19

20 (13.1)

0 (0)

20 (12.1)

ART experience prior DTG start

0.601

ART- experienced

140 (91.5)

12 (100)

152 (92.1)

ART- naïve

13 (8.5)

0 (0)

13 (7.9)

Duration on DTG (years)

1 - < 2

39 (25.5)

4 (33.3)

43 (26.1)

0.862

2 - < 3

46 (30.1)

3 (25.0)

49 (29.7)

3 - 4

68 (44.4)

5 (41.7)

73 (44.2)

Reported history of side effects^ after DTG start

0.001

No

130 (85.0)

7 (58.3)

137 (83.0)

Yes

23 (15.0)

5 (41.7)

28 (17.0)

Viral load at DTG start

0.731

Suppressed (< 1000 copies/ml)

133 (86.9)

12 (100)

145 (87.9)

Unsuppressed (≥ 1000 copies/ml)

5 (3.3)

0 (0)

5 (3.0)

Unknown/Not applicable^¶

15 (9.8)

0 (0)

15 (9.1)

Current viral load

0.609

Suppressed (< 1000 copies/ml)

142 (92.8)

11 (91.7)

153 (92.7)

Unsuppressed (≥ 1000 copies/ml)

5 (3.3)

0 (0)

5 (3.2)

Unknown (Missing data)

6 (3.9)

1 (8.3)

7 (4.2)

Involvement in physical activity

0.691

No

26 (17.0)

4 (33.3)

30 (18.2)

Yes

127 (83.0)

8 (66.7)

135 (81.8)

Family history of hypertension or diabetes mellitus

0.445

No

79 (51.6)

5 (41.7)

84 (50.9)

Yes

61 (39.8)

7 (58.3)

68 (41.2)

Unknown

13 (8.5)

0 (0)

13 (7.9)

Smoking, alcohol and substance use

0.939

No

153 (100)

11 (91.7)

164 (99.4)

Yes

0 (0)

1 (8.3)

1 (0.6)

Blood pressure

0.164

Normal (< 90th percentile /< 120/80 mmHg)

90 (58.8)

8 (66.7)

98 (59.4)

Elevated (≥ 90th percentile / ≥ 120/80 mmHg)

63 (41.2)

4 (33.3)

67 (40.6)

Blood glucose

0.570

Normal (FBG < 5.6mmol/L or RBG < 11.1mmol/L)

141 (92.2)

12 (100)

153 (92.7)

Pre-diabetic (FBG 5.6–6.9 mmol/L)

12 (7.8)

0 (0)

12 (7.3)

Diabetic (FBG ≥ 7.0 mmol/L)

0 (0)

0 (0)

0 (0)

Triglycerides

0.887

Acceptable (< 90 mg/dl)

90 (58.8)

9 (75.0)

99 (60)

Borderline (90–129 mg/dl)

47 (30.7)

3 (25.0)

50 (30.3)

High (≥ 130 mg/dl)

16 (10.5)

0 (0)

16 (9.7)

Total cholesterol

0.081

Acceptable (< 170 mg/dl)

141 (92.2)

10 (83.3)

151 (91.5)

Borderline (170–199 mg/dl)

12 (7.8)

1 (8.3)

13 (7.9)

High (≥ 200 mg/dl)

0 (0)

1 (8.3)

1 (0.6)

Low-density lipoprotein cholesterol

0.180

Acceptable (< 110 mg/dl)

142 (92.8)

10 (83.3)

152 (92.1)

Borderline (110–129 mg/dl)

11 (7.2)

2 (16.7)

13 (7.9)

High (≥ 130 mg/dl)

0 (0)

0 (0)

0 (0)

High-density lipoprotein cholesterol

0.093

Acceptable (> 45 mg/dl)

30 (19.6)

4 (33.3)

34 (20.6)

Borderline (40–45 mg/dl)

33 (21.6)

3 (25.0)

36 (21.8)

Low (< 40 mg/dl)

90 (58.8)

5 (41.7)

95 (57.6)