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Table 1 Effect of ART regimen on excessive BMI increase, $ adjusted for confounding factors

From: Effect of dolutegravir-based versus efavirenz-based antiretroviral therapy on excessive weight gain in adult treatment-naïve HIV patients at Matsanjeni health center, Eswatini: a retrospective cohort study

 

No Excessive BMI increase

Excessive BMI increase

aOR

[95%CI]

N

%

N

%

Total

237

75.0

79

25.0

  

Gender

    

NS

 

Female

153

78.5

42

21.5

  

Male

84

69.4

37

30.6

  

Age (median, IQR)

37

(31–45)

38

(30–34)

NS

 

Economic status

    

NS

 

Middle

12

60.0

8

40.0

  

Low

225

76.0

71

24.0

  

Educational level

    

NS

 

Primary

138

79.8

35

20.2

  

Secondary

93

69.9

40

30.1

  

Tertiary

6

60.0

4

40.0

  

CD4 at baseline (median, IQR)

343

(215–462)

297

(142–476)

NS

 

WHO STAGE

    

NS

 

1

139

74.7

47

25.3

  

2

75

79.8

19

20.2

  

3

21

65.6

11

34.4

  

4

2

50.0

2

50.0

  

Regimen

      

EFV-based

136

85.0

24

15.0

1

 

DTG-based

101

64.7

55

35.3

2.61**

[1.39,4.93]

  1. EFV: efavirenz; DTG: dolutergravir; BMI:body mass index; aOR: adjusted odds ratio;
  2. IQR: interquartile range; NS: not significant; * p < 0.05, ** p < 0.01, *** p < 0.001
  3. $ BMI excessive increase: increase at 24 months ART of at least one category compared to baseline, and with BMI > = 25 at 24 months ART