Skip to main content

Table 5 Determinants of mortality

From: Determinants of survival of adolescents receiving antiretroviral therapy in the Centre Region of Cameroon: a multi-centered cohort-analysis

Characteristics

Univariate

Analysis

Multivariate

Analysis

Hazard Ratio

(95% CI)

P-value

Hazard Ratio

(95% CI)

P-value

Gender

Male

1

 

Female

1.081 (0.874–1.336)

0.473

Age in years

10–14

1

 

15–19

1.167 (0.939–1.450)

0.163

Geographical setting

Urban

1

 

1

 

Rural

1.703 (1.268–2.286)

0.0001

6.521 (3.776–11.261)

0.0001

Level of Education

Primary

1

 

Secondary

1.039 (0.810–1.332)

0.765

Tertiary

1.190 (0.483–2.933)

0.705

None

1.121 (0.411–3.058)

0.823

Disclosure of HIV to study participants

Yes

1

 

No

1.280 (1.007–1.627)

0.044

Parental Status

Orphan

1.200 (0.963–1.495)

0.105

Non orphan

1

 

Baseline CD4 count

≥ 500 cell/mm3

1

 

 

< 500 cell/mm3

1.695 (1.230–2.337)

0.001

  

WHO clinical stage

Stage I/II

1

 

 

Stage III/IV

1.039 (0.801–1.349)

0.773

Retained in care

Yes

1

 

1

 
 

No

1.813 (0.962–3.418)

0.066

2.399 (1.156–4.979)

0.019

Anemia at start

Yes

1

 

1

 

No

0.373 (0.204–0.684)

0.001

0.207 (0.067–0.632)

0.006

Opportunistic infection

Yes

1.333 (0.961–1.850)

0.086

 

No

1

 

Treatment Regimen

First line

1.202 (0.815–1.771)

0.354

 

Second line

1

 

Cotrimoxazole prophylaxis

Yes

1

 

 

No

0.820 (0.536–1.254)

0.360

Exposure to NVP prophylaxis for PMTCT

Yes

1

 

 

No

1.845 (1.134–3.003)

0.014

Mode of Transmission

Vertical

1

 

 

Horizontal

2.575 (1.464–4.530)

0.001