Table 1 Genotypic drug resistance interpretation according to the HIV drug resistance database system

Gene coding regions

Mutations

ARV drugs

Interpretation ^a

PR

M 46I, L76V, 184 V, K20T, Q58E, G73S

Atazanavir (ATV/r)

H

H

Darunavir (DRV/r)

I

Fosamprenavir (FPV/r)

H

Indinavir (IDV/r)

H

Lopinavir (LPV/r)

H

H

Nelfinavir (NFV)

H

Saquinavir (SQV/r)

H

Tipranavir (TPV/r)

I

RT

NRTI relevant

M41L, E 44 A, F77L, M184V, L210W, T215Y, K219N

Abacavir (ABC)

H

H

Zidovudine (AZT)

H

H

Stavudine (d4T)

H

Didanosine (DDI)

H

Emtricitabine (FTC)

H

H

Lamivudine (3TC)

H

H

Tenofovir (TDF)

H

H

NNRTI relevant

K101H, Y181C

Doravirine (DOR)

P

Efavirenz (EFV)

I

I

Etravirine (ETR)

I

I

Nevirapine (NVP)

H

H

Rilpivirine (RPV)

I

I

IN

INSTI relevant

Bictegravir (BIC)

S

S

Cabotegravir (CAB)

S

Dolutegravir (DTG)

S

S

Elvitegravir (EVG)

S

S

Raltegravir (RAL)

S

S