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Table 2 Potential predictors associated with virological treatment failure (>400 HIV RNA cop/ml) after 6 months of initiating ART

From: Antiretroviral treatment adherence and its determinants in Sub-Saharan Africa: a prospective study at Yaounde Central Hospital, Cameroon

 

Self reported adherence

CD4 count change

Pharmacy refill history

 

100%

<100%

Immunological success

Immunological failure

Regular, continuous

Irregular or interrupted

Total (Nb)

140

25

51

14

147

47

Virological success (Nb)

125

22

44

6

140

29

Virological failure (Nb)

15

3

7

8

7

18

OR (95%CI)

1.13 (0.30-4.25)

7.78 (1.68-36.0)

12.4 (4.75-32.4)

Sensitivity

0.17

0.53

0.72

Specificity

0.85

0.88

0.83

Positive predictive value

0.12

0.57

0.38

Negative predictive value

0.83

0.86

0.95

Positive likelihood ratio

1.13

1.23

4.23

Negative likelihood ratio

0.97

0.53

0.34

  1. Viral load measurement was available for 206 patients. Immunological success means a rise above 100 cells/μl; immunological failure means a drop to pre-treatment levels or <100 cells/μl,)