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Table 1 Clinical characteristics of patients in NNRTI and PI group.

From: Rapid CD4 decline after interruption of non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy in a resource-limited setting

Characteristics

NNRTI N = 85

PI N = 14

P-value

Age, mean ± SD, years

40.6 ± 8.8

40.7 ± 10.9

0.776

Gender, number (%)

  

0.993

   Male

38 (45)

7 (50)

 

   Female

47 (55)

7 (50)

 

Duration of HIV diagnosis, median (IQR), months

65 (47–94)

72 (47–109)

0.788

History of OIs, number (%)

10 (12)

2 (14)

0.992

HBV co-infection, number (%)

6 (7)

1 (7)

0.957

HCV co-infection, number (%)

3 (4)

0 (0)

0.451

NRTI backbone in HAART prior to TI, number (%)

  

0.480

   - Stavudine + lamivudine

43 (51)

7 (50)

 

   - Zidovudine + lamivudine

35 (41)

5 (36)

 

   - Zidovudine + didanosine

4 (5)

2 (14)

 

   - Didanosine + lamivudine

3 (3)

0 (0)

 

Duration of HAART prior to TI, median (IQR), months

46 (36–64)

59 (37–76)

0.968

Nadir CD4 cell count, median (IQR), cells/mm3

147 (57–215)

217 (63–345)

0.186

Baseline CD4 cell counts at TI, median (IQR), cells/mm3

530 (441–657)

586 (381–747)

0.924

  1. OIs = opportunistic infections, HBV = hepatitis B virus, HCV = hepatitis C virus