Table 1 Work definitions for MetS
From: Metabolic syndrome in HIV-infected individuals: underlying mechanisms and epidemiological aspects
Definition | EGIR (1999)[13] | NCEP/ATP III (2001)[14] | AHA-NHLBI (2005)[15] | IDF (2006)[16] |
|---|---|---|---|---|
Mandatory criteria | Insulin resistance defined as the top 25% of the fasting insulin values among nondiabetic individuals | None | None | Waist circumference# with ethnicity-specific values |
Aditional criteria | At least two of the following: | At least three of the following: | At least three of the following: | At least two of the following: |
Central obesity | Waist circumference ≥ 94 cm (male), ≥ 80 cm (female) | Waist circumference ≥ 102 cm or 40 inches (male), ≥ 88 cm or 35 inches (female) | Waist circumference ≥ 102 cm or 40 inches (male), ≥ 88 cm or 35 inches (female) | See mandatory criteria |
Dyslipidemia | TG ≥ 2.0 mmol/L and/or HDL-C < 1.0 mmol/L or treated for dyslipidemia | TG ≥ 1.7 mmol/L (150 mg/dl) OR HDL-C < 40 mg/dL (male), < 50 mg/dL (female) | TG ≥ 1.7 mmol/L (150 mg/dl) OR HDL-C < 40 mg/dL (male), < 50 mg/dL (female) | TG > 150 mg/dL (1.7 mmol/L), or specific treatment for this lipid abnormality OR HDL-C < 40 mg/dL (1.03 mmol/L) in males, < 50 mg/dL (1.29 mmol/L) in females, or specific treatment for this lipid abnormality |
Blood pressure | ≥ 140/90 mmHg or antihypertensive medication | ≥ 130/85 mmHg or antihypertensive medication | ≥130/85 mmHg | Systolic BP > 130 OR diastolic BP >85 mmHg, or treatment of previously diagnosed hypertension |
Glucose metabolism | Fasting plasma glucose ≥ 6.1 mmol/L | Fasting plasma glucose ≥ 6.1 mmol/L (110 mg/dl) | Fasting plasma Glucose ≥ 100 mg/dL | Raised fasting plasma glucose: >100 mg/dL (5.6 mmol/L), or previously diagnosed tDM |