%PDF-1.6
%
1 0 obj
<>
endobj
2 0 obj
<>stream
2020-07-18T15:28:05+05:30
Springer
2020-07-20T13:27:59+02:00
2020-07-20T13:27:59+02:00
Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version)
HIV infection,Highly active antiretroviral therapy,Cohort studies,Darunavir
application/pdf
https://doi.org/10.1186/s12981-020-00302-2
BioMed Central
AIDS Research and Therapy, https://doi.org/10.1186/s12981-020-00302-2
HIV infection
Highly active antiretroviral therapy
Cohort studies
Darunavir
Effectiveness of the combination elvitegravir/cobicistat/tenofovir/emtricitabine (EVG/COB/TFV/FTC) plus darunavir among treatment-experienced patients in clinical practice: a multicentre cohort study
Inés Suárez-García
Cristina Moreno
Marta Ruiz-Algueró
María Jesús Pérez-Elías
Marta Navarro
Marcos Díez Martínez
Pompeyo Viciana
Laura Pérez-Martínez
Miguel Górgolas
Concha Amador
Miguel Alberto de Zárraga
Inma Jarrín
Santiago Moreno
Inma Jarrín
David Dalmau
Maria Luisa Navarro
Maria Isabel González
Federico Garcia
Eva Poveda
Jose Antonio Iribarren
Félix Gutiérrez
Rafael Rubio
Francesc Vidal
Juan Berenguer
Juan González
M Ángeles Muñoz-Fernández
Inmaculada Jarrin
Belén Alejos
Cristina Moreno
Carlos Iniesta
Luis Miguel Garcia Sousa
Nieves Sanz Perez
Marta Rava
M Ángeles Muñoz-Fernández
Irene Consuegra Fernández
Esperanza Merino
Gema García
Irene Portilla
Iván Agea
Joaquín Portilla
José Sánchez-Payá
Juan Carlos Rodríguez
Lina Gimeno
Livia Giner
Marcos Díez
Melissa Carreres
Sergio Reus
Vicente Boix
Diego Torrús
Ana López Lirola
Dácil García
Felicitas Díaz-Flores
Juan Luis Gómez
María del Mar Alonso
Ricardo Pelazas
Jehovana Hernández
María Remedios Alemán
María Inmaculada Hernández
Víctor Asensi
Eulalia Valle
María Eugenia Rivas Carmenado
Tomas Suarez-Zarracina Secades
Laura Pérez Is
Rafael Rubio
Federico Pulido
Otilia Bisbal
Asunción Hernando
Lourdes Domínguez
David Rial Crestelo
Laura Bermejo
Mireia Santacreu
José Antonio Iribarren
Julio Arrizabalaga
María José Aramburu
Xabier Camino
Francisco Rodríguez-Arrondo
Miguel Ángel von Wichmann
Lidia Pascual Tomé
Miguel Ángel Goenaga
Mª Jesús Bustinduy
Harkaitz Azkune
Maialen Ibarguren
Aitziber Lizardi
Xabier Kortajarena
Mª Pilar Carmona Oyaga
Maitane Umerez Igartua
Félix Gutiérrez
Mar Masiá
Sergio Padilla
Andrés Navarro
Fernando Montolio
Catalina Robledano
Joan Gregori Colomé
Araceli Adsuar
Rafael Pascual
Marta Fernández
Elena García
José Alberto García
Xavier Barber
Roberto Muga
Arantza Sanvisens
Daniel Fuster
Juan Berenguer
Juan Carlos López Bernaldo de Quirós
Isabel Gutiérrez
Margarita Ramírez
Belén Padilla
Paloma Gijón
Teresa Aldamiz-Echevarría
Francisco Tejerina
Francisco José Parras
Pascual Balsalobre
Cristina Diez
Leire Pérez Latorre
Chiara Fanciulli
Francesc Vidal
Joaquín Peraire
Consuelo Viladés
Sergio Veloso
Montserrat Vargas
Montserrat Olona
Anna Rull
Esther Rodríguez-Gallego
Verónica Alba
Alfonso Javier Castellanos
Miguel López-Dupla
Marta Montero Alonso
José López Aldeguer
Marino Blanes Juliá
María Tasias Pitarch
Iván Castro Hernández
Eva Calabuig Muñoz
Sandra Cuéllar Tovar
Miguel Salavert Lletí
Juan Fernández Navarro
Juan González-Garcia
Francisco Arnalich
José Ramón Arribas
Jose Ignacio Bernardino de la Serna
Juan Miguel Castro
Luis Escosa
Pedro Herranz
Victor Hontañón
Silvia García-Bujalance
Milagros García López-Hortelano
Alicia González-Baeza
Maria Luz Martín-Carbonero
Mario Mayoral
Maria Jose Mellado
Rafael Esteban Micán
Rocio Montejano
María Luisa Montes
Victoria Moreno
Ignacio Pérez-Valero
Berta Rodés
Talia Sainz
Elena Sendagorta
Natalia Stella Alcáriz
Eulalia Valencia
José Ramón Blanco
José Antonio Oteo
Valvanera Ibarra
Luis Metola
Mercedes Sanz
Laura Pérez-Martínez
Piedad Arazo
Gloria Sampériz
David Dalmau
Angels Jaén
Montse Sanmartí
Mireia Cairó
Javier Martinez-Lacasa
Pablo Velli
Roser Font
Mariona Xercavins
Noemí Alonso
Maria Rivero Marcotegui
Jesús Repáraz
María Gracia Ruiz de Alda
María Teresa de León Cano
Beatriz Pierola Ruiz de Galarreta
María José Amengual
Gemma Navarro
Manel Cervantes Garcia
Sonia Calzado Isbert
Marta Navarro Vilasaro
Ignacio de los Santos
Jesus Sanz Sanz
Ana Salas Aparicio
Cristina Sarria Cepeda
Lucio Garcia-Fraile Fraile
Enrique Martín Gayo
Santiago Moreno
José Luis Casado Osorio
Fernando Dronda Nuñez
Ana Moreno Zamora
Maria Jesús Pérez Elías
Carolina Gutiérrez
Nadia Madrid
Santos del Campo Terrón
Sergio Serrano Villar
Maria Jesús Vivancos Gallego
Javier Martínez Sanz
Usua Anxa Urroz
Tamara Velasco
Enrique Bernal
Alfredo Cano Sanchez
Antonia Alcaraz García
Joaquín Bravo Urbieta
Angeles Muñoz Perez
Maria Jose Alcaraz
Maria del Carmen Villalba
Federico García
José Hernández Quero
Leopoldo Muñoz Medina
Marta Alvarez
Natalia Chueca
David Vinuesa García
Clara Martinez-Montes
Carlos Guerrero Beltran
Adolfo de Salazar Gonzalerz
Ana Fuentes Lopez
Montserrat Raposo Utrilla
Jorge Del Romero
Carmen Rodríguez
Teresa Puerta
Juan Carlos Carrió
Mar Vera
Juan Ballesteros
Oskar Ayerdi
Antonio Antela
Elena Losada
Melchor Riera
María Peñaranda
María Leyes
Mª Angels Ribas
Antoni A Campins
Carmen Vidal
Francisco Fanjul
Javier Murillas
Francisco Homar
Jesús Santos
Crisitina Gómez Ayerbe
Isabel Viciana
Rosario Palacios
Carmen Pérez López
Carmen Maria Gonzalez-Domenec
Pompeyo Viciana
Nuria Espinosa
Luis Fernando López-Cortés
Daniel Podzamczer
Arkaitz Imaz
Juan Tiraboschi
Ana Silva
María Saumoy
Paula Prieto
Esteban Ribera
Adrian Curran
Julián Olalla Sierra
Javier Pérez Stachowski
Alfonso del Arco
Javier de la torre
José Luis Prada
José María García de Lomas Guerrero
Onofre Juan Martínez
Francisco Jesús Vera
Lorena Martínez
Josefina García
Begoña Alcaraz
Amaya Jimeno
Angeles Castro Iglesias
Berta Pernas Souto
Alvaro Mena de Cea
Josefa Muñoz
Miren Zuriñe Zubero
Josu Mirena Baraia-Etxaburu
Sofía Ibarra Ugarte
Oscar Luis Ferrero Beneitez
Josefina López de Munain
Mª Mar Cámara López
Mireia de la Peña
Miriam Lopez
Iñigo Lopez Azkarreta
Carlos Galera
Helena Albendin
Aurora Pérez
Asunción Iborra
Antonio Moreno
Maria Angustias Merlos
Asunción Vidal
Marisa Meca
Concha Amador
Francisco Pasquau
Javier Ena
Concha Benito
Vicenta Fenoll
Concepcion Gil Anguita
Jose Tomas Algado Rabasa
Inés Suárez-García
Eduardo Malmierca
Patricia González-Ruano
Dolores Martín Rodrigo
Mª Pilar Ruiz Seco
Mohamed Omar Mohamed-Balghata
María Amparo Gómez Vidal
Miguel Alberto de Zarraga
Vicente Estrada Pérez
Maria Jesus Téllez Molina
Jorge Vergas García
Juncal Pérez-Somarriba Moreno
Miguel Górgolas
Alfonso Cabello
Beatriz Álvarez
Laura Prieto
José Sanz Moreno
Alberto Arranz Caso
Cristina Hernández Gutiérrez
María Novella Mena
María José Galindo Puerto
Ramón Fernando Vilalta
Ana Ferrer Ribera
Antonio Rivero Román
Antonio Rivero Juárez
Pedro López López
Isabel Machuca Sánchez
Mario Frias Casas
Angela Camacho Espejo
Miguel Cervero Jiménez
Rafael Torres Perea
Juan A Pineda
Pilar Rincón Mayo
Juan Macias Sanchez
Nicolas Merchante Gutierrez
Luis Miguel Real
Anais Corma Gomez
Marta Fernandez Fuertes
Alejandro Gonzalez-Serna
Eva Poveda
Alexandre Pérez
Manuel Crespo
Luis Morano
Celia Miralles
Antonio Ocampo
Guillermo Pousada
10.1186/s12981-020-00302-2
2010-04-23
true
springer.com
springerlink.com
https://doi.org/10.1186/s12981-020-00302-2
10.1186/s12981-020-00302-2
1742-6405
journal
AIDS Research and Therapy
The Author(s)
2010-04-23
true
10.1186/s12981-020-00302-2
noindex
springer.com
springerlink.com
VoR
uuid:6c951bcc-fa15-4db6-8c81-e679e082fb71
uuid:a954e5b2-968a-4c3d-a660-f6a64655539e
default
1
converted
uuid:01ce88ac-4e78-424c-9cf4-dd8809b3137e
converted to PDF/A-2b
pdfToolbox
2020-07-18T15:29:28+05:30
2
B
Inés Suárez-García
http://orcid.org/0000-0002-7016-716X
http://ns.adobe.com/pdfx/1.3/
pdfx
Adobe Document Info PDF eXtension Schema
external
Mirrors crossmark:MajorVersionDate
CrossmarkMajorVersionDate
Text
external
Mirrors crossmark:CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
Mirrors crossmark:DOI
doi
Text
external
Mirrors crossmark:CrosMarkDomains
CrossMarkDomains
seq Text
internal
A name object indicating whether the document has been modified to include trapping information
robots
Text
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
http://crossref.org/crossmark/1.0/
crossmark
Crossmark Schema
internal
Usual same as prism:doi
DOI
Text
external
The date when a publication was publishe.
MajorVersionDate
Text
internal
CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
CrossMarkDomains
CrossMarkDomains
seq Text
http://prismstandard.org/namespaces/basic/2.0/
prism
Prism Schema
external
This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.
url
URI
external
The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL).
doi
Text
external
ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.
issn
Text
internal
Volume number
volume
Text
internal
Issue number
number
Text
internal
Starting page
startingPage
Text
internal
Ending page
endingPage
Text
external
The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary.
aggregationType
Text
external
Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”
publicationName
Text
external
Copyright
copyright
Text
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
DocumentID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
Springer Nature ORCID Schema
http://springernature.com/ns/xmpExtensions/2.0/
sn
authorInfo
Bag AuthorInformation
external
Author information: contains the name of each author and his/her ORCiD (ORCiD: Open Researcher and Contributor ID). An ORCiD is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors.
AuthorInformation
http://springernature.com/ns/xmpExtensions/2.0/authorInfo/
author
Specifies the types of author information: name and ORCID of an author.
name
Text
Gives the name of an author.
orcid
URI
Gives the ORCID of an author.
http://www.niso.org/schemas/jav/1.0/
jav
NISO
external
Values for Journal Article Version are one of the following:
AO = Author’s Original
SMUR = Submitted Manuscript Under Review
AM = Accepted Manuscript
P = Proof
VoR = Version of Record
CVoR = Corrected Version of Record
EVoR = Enhanced Version of Record
journal_article_version
Closed Choice of Text
endstream
endobj
3 0 obj
<>
endobj
7 0 obj
[9 0 R 10 0 R 11 0 R 12 0 R 13 0 R 14 0 R 15 0 R 16 0 R 17 0 R 18 0 R 19 0 R 20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R]
endobj
9 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR1:26)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[135.947 704.391 140.867 692.224]>>
endobj
10 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR2:27)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[218.125 644.391 223.044 632.224]>>
endobj
11 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR3:28)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[158.266 572.391 163.186 560.224]>>
endobj
12 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR4:29)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[169.193 572.391 174.112 560.224]>>
endobj
13 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR5:30)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[211.239 488.391 216.159 476.224]>>
endobj
14 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR6:31)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[138.673 404.391 143.593 392.224]>>
endobj
15 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR7:32)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[149.38 404.391 154.299 392.224]>>
endobj
16 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR8:33)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[252.481 380.391 257.4 368.224]>>
endobj
17 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR9:34)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[263.882 380.391 268.802 368.224]>>
endobj
18 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR10:35)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[59.8876 284.391 69.7268 272.224]>>
endobj
19 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR5:30)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[209.392 212.391 214.312 200.224]>>
endobj
20 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR6:31)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[218.849 212.391 223.769 200.224]>>
endobj
21 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR11:36)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[228.306 212.391 238.145 200.224]>>
endobj
22 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR12:37)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[435.474 560.391 445.313 548.224]>>
endobj
23 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR13:38)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[451.686 560.391 461.525 548.224]>>
endobj
24 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR14:39)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[308.115 152.391 318.346 140.224]>>
endobj
25 0 obj
<>/Subtype/Link/Dest(12981_2020_302_Article.indd:CR15:40)/F 4/Type/Annot/H/N/Border[0 0 0]/AP<>/Rect[323.069 152.391 333.301 140.224]>>
endobj
6 0 obj
<>/ProcSet[/PDF/Text]/Font<>/XObject<>>>
endobj
4 0 obj
<>stream
x\rVvo>BƖO /kdɖ="u4?DWņHhE4y;IrW,0̭;9h,P\.ѿ"ˏg%V,8KHHYQUZb9{яsou]XE"˂.**0r
=uGW_D_ފt_^C{x֏2//{Vwb'A[a]zq/LB_/~ƓExP,M(^g:}bOVXޝUg9 Q$*2"M#>v]W/"
*oմb5ݵxO[")`3/?vϽ !o+_TA 5ICf/\M[QXDAb
nt/ry9/kFAY<*wЃ7bcpM=-{\y m6m<",G{AA)2,-Ro4>"ﶭᶿ7~\yK!ϔ{(ɞ^L%a{ߒ,zh8Am9Aj[QO [#=l>APM۲%b6x/⭺XY
+խfz;OPB{5#I^AwmA)hQeb
?1
u
Jl/XnϵxpSݱы']! J3(8y-э~Bt!=NYh:;QKƶ%]}g{A|h\m/s,Fe=dŚeUz?ʽ_#
Y)
^~%^xs N2o.k'K?ά_q䝳=\]u_~yjX?_zyQଞ@}KL3~i:$ICAaY%Lef#K'J!-v2)!T0@vB} _#N/{JHδ̎ά,'QD+I+ni֏7탬"wmA[q ;51"էu QA^95)CPZWWeǰLiܰk?ѥ+u^p.Ӎ#3RF(>3'r@yRz8YC82'G@t={ ytBq Ab#$A{0HAD{Cꍕ{2Aq$L@La:'&2?H UQx
#*j/Wo0I ,Cj@e3~>)l2ִ Hxe3=5