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  1. Although highly active antiretroviral therapy (HAART) reduces mortality in the developed world, it remains undocumented in resource-poor settings. We assessed the effect of HAART on patient mortality and tuber...

    Authors: Degu Jerene, Are Næss and Bernt Lindtjørn

    Citation: AIDS Research and Therapy 2006 3:10

    Content type: Research

    Published on:

  2. Co-infection with hepatitis B virus (HBV) and human immunodeficiency virus (HIV) is not infrequent as both share same route of exposure. The risk of developing chronic hepatitis B virus is 6%, in general popul...

    Authors: Patricia Cornejo-Juárez, Patricia Volkow-Fernández, Kenia Escobedo-López, Diana Vilar-Compte, Guillermo Ruiz-Palacios and Luis Enrique Soto-Ramírez

    Citation: AIDS Research and Therapy 2006 3:9

    Content type: Research

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  3. Co-infections of human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (M. Tb) are steadily increasing and represent a major health crisis in many developing countries. Both pathogens individually sti...

    Authors: Soichi Haraguchi, Noorbibi K Day, Wasu Kamchaisatian, Macarena Beigier-Pompadre, Steffen Stenger, Nutthapong Tangsinmankong, John W Sleasman, Salvatore V Pizzo and George J Cianciolo

    Citation: AIDS Research and Therapy 2006 3:8

    Content type: Research

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  4. Intracellular levels of glutathione are depleted in patients with acquired immunodeficiency syndrome in whom the risk of tuberculosis, particularly disseminated disease is many times that of healthy individual...

    Authors: Vishwanath Venketaraman, Tatanisha Rodgers, Rafael Linares, Nancy Reilly, Shobha Swaminathan, David Hom, Ariel C Millman, Robert Wallis and Nancy D Connell

    Citation: AIDS Research and Therapy 2006 3:5

    Content type: Research

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  5. The objective of this study was to evaluate the safety of twice daily, intra-vaginal use of 0.5% PRO 2000 Gel for fourteen days in HIV un-infected women at lower as well as higher risk for HIV acquisition, in ...

    Authors: Joshi Smita, Dutta Soma, Bell Beverly, Profy Albert, Kuruc JoAnn, Gai Fang, Cianciola Missy, Soto-Torres Lydia, Panchanadikar Anjali, Risbud Arun, Mehendale Sanjay and Reynolds Steven J

    Citation: AIDS Research and Therapy 2006 3:4

    Content type: Research

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  6. Partial or complete seroreversion for HIV-1, or incomplete antibody evolution are relatively rare events that have so far only been described in patients treated with HAART early after virus infection. Whether...

    Authors: Marion Cornelissen, Suzanne Jurriaans, Jan M Prins, Margreet Bakker and Antoinette C van der Kuyl

    Citation: AIDS Research and Therapy 2006 3:3

    Content type: Short report

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  7. Protease inhibitors, particularly ritonavir, causes significant gastrointestinal disturbances such as nausea, even at low doses. This ritonavir-induced nausea could be related to its oxidative stress in the gu...

    Authors: Han Aung, Sangeeta Mehendale, Wei-Tien Chang, Chong-Zhi Wang, Jing-Tian Xie and Chun-Su Yuan

    Citation: AIDS Research and Therapy 2005 2:12

    Content type: Research

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  8. Implementation of programs for the prevention of mother-to-child transmission (PMTCT) of HIV faces a variety of barriers and challenges. The assessment of these challenges has generally been conducted in large...

    Authors: Francis Bajunirwe and Michael Muzoora

    Citation: AIDS Research and Therapy 2005 2:10

    Content type: Research

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  9. Episomal 2-long terminal repeat (LTR) HIV-1 cDNA, a by-product of HIV-1 infection, is used in clinical trials as a marker for ongoing viral replication. It would be useful to employ 2-LTR cDNA to monitor crypt...

    Authors: Chong Xu, Joseph A Politch, Kenneth H Mayer and Deborah J Anderson

    Citation: AIDS Research and Therapy 2005 2:9

    Content type: Research

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  10. RNA and DNA aptamers specific for HIV-1 reverse transcriptase (RT) can inhibit reverse transcription in vitro. RNA aptamers have been shown to potently block HIV-1 replication in culture. We previously reported m...

    Authors: Timothy S Fisher, Pheroze Joshi and Vinayaka R Prasad

    Citation: AIDS Research and Therapy 2005 2:8

    Content type: Research

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  11. Murine leukemia virus (MLV) vector particles can be pseudotyped with a truncated variant of the human immunodeficiency virus type 1 (HIV-1) envelope protein (Env) and selectively target gene transfer to human ...

    Authors: Sandra Siegert, Sonja Thaler, Ralf Wagner and Barbara S Schnierle

    Citation: AIDS Research and Therapy 2005 2:7

    Content type: Methodology

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  12. The neurofilament is a major structural component of myelinated axons. Increased cerebrospinal fluid (CSF) concentrations of the light chain of the neurofilament protein (NFL) can serve as a sensitive indicato...

    Authors: Magnus Gisslén, Lars Rosengren, Lars Hagberg, Steven G Deeks and Richard W Price

    Citation: AIDS Research and Therapy 2005 2:6

    Content type: Research

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  13. In Cambodia, nearly half of pregnant women attend antenatal care (ANC), which is an entry point of services for prevention of mother-to-child transmission of HIV (PMTCT). However, most of ANC services are prov...

    Authors: Koum Kanal, Thai Leang Chou, Ly Sovann, Yasuo Morikawa, Yumi Mukoyama and Kazuhiro Kakimoto

    Citation: AIDS Research and Therapy 2005 2:5

    Content type: Short report

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  14. Observational studies have suggested that low serum vitamin levels are associated with increased mother-to-child transmission (MTCT) of HIV and increased preterm delivery. We aimed to determine the efficacy of...

    Authors: Edward J Mills, Ping Wu, Dugald Seely and Gordon H Guyatt

    Citation: AIDS Research and Therapy 2005 2:4

    Content type: Research

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  15. Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a u...

    Authors: Karen S Slobod, Chris Coleclough, Scott A Brown, John Stambas, Xiaoyan Zhan, Sherri Surman, Bart G Jones, Amy Zirkel, Pamela J Freiden, Brita Brown, Robert Sealy, Mattia Bonsignori and Julia L Hurwitz

    Citation: AIDS Research and Therapy 2005 2:3

    Content type: Hypothesis

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  16. Protease inhibitors (PIs) block HIV-1 maturation into an infectious virus particle by inhibiting the protease processing of gag and gag-pol precursor proteins. We have used a simple anti-HIV-1 p24 Western blot...

    Authors: Heather A Baird, Andre J Marozsan, Michael M Lederman, Alan Landay, Donna Mildvan, Daniel R Kuritzkes, Harold A Kessler and Eric J Arts

    Citation: AIDS Research and Therapy 2005 2:2

    Content type: Research

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  17. RNA based antiviral approaches against HIV-1 are among the most promising for long-term gene therapy. These include ribozymes, aptamers (decoys), and small interfering RNAs (siRNAs). Lentiviral vectors are ide...

    Authors: Akhil Banerjea, Ming-Jie Li, Leila Remling, John Rossi and Ramesh Akkina

    Citation: AIDS Research and Therapy 2004 1:2

    Content type: Research

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